Abstract
(1) Cell fusion studies have shown that β-adrenergic receptors concerned in adenylate cyclase (AC) activation can move from one cell to another. (2) If agonists such as protein hormones are joined to a large rigid carrier molecule such as a virus, they may exhibit superpotency that reflects superaffinity. (3) Catecholamine desensitization as studied with turkey erythrocytes is due to a regulatory defect at the level of nucleotide regulatory proteins (Ns -protein J. In general this article concerns some interactions of the hormone receptor-N-protein -AC complex.
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© 1984 Plenum Press, New York
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Schulster, D., Salmon, M.D. (1984). Hormone Receptor — Adenylate Cyclase Interaction: Superpotency, Superaffinity and Desensitization Phenomena. In: Reid, E., Cook, G.M.W., Morré, D.J. (eds) Investigation of Membrane-Located Receptors. Methodological Surveys in Biochemistry and Analysis, vol 13. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4631-9_13
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DOI: https://doi.org/10.1007/978-1-4684-4631-9_13
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