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Biogenetic Autonomy of Mitochondria and Its Limits

Some Questions and New Approaches to Their Answer

  • Chapter
Membrane Biogenesis

Abstract

The past ten years have seen such an almost explosive growth of efforts devoted to studies on mitochondrial biogenesis that they occupy at least as much contemporary journal space as do studies on mitochondrial function and energetics, their much more venerable companions. The results of this endeavor have been fairly spectacular: the documentation of the existence and the characteristics, in molecular terms, of a novel and separate system for the maintenance, duplication, and expression of genetic information within the organelle and its interaction with the classical nucleocytosolic system of the eukaryotic cell (for recent reviews see refs. 1–10).

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Authors and Affiliations

  1. Mitochondrial Biogenesis Group, Chemical Laboratories, Indiana University, Bloomington, Indiana, 47401, USA

    Henry R. Mahler, Roberto N. Bastos, Fred Feldman, Urs Flury, Chi Chung Lin & Sem H. Phan

  2. Department of Genetics, Ohio State University, 43210, Columbus, Ohio, USA

    Philip S. Perlman

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  1. Henry R. Mahler
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  1. Department of Biochemistry, The Public Health Research Institute of the City of New York, Inc., New York, New York, USA

    Alexander Tzagoloff

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Mahler, H.R. et al. (1975). Biogenetic Autonomy of Mitochondria and Its Limits. In: Tzagoloff, A. (eds) Membrane Biogenesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2136-1_2

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