Polychlorinated biphenyls: Occurrence and biological effects

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Residue Reviews

Part of the book series: Residue Reviews ((RECT,volume 44))

Abstract

The polychlorinated biphenyl (PCB’s) have come to prominence recently because of the substantial levels that have been found in the environment and because of claims that feed contaminated by these materials had caused reproductive failure in chickens (Picrirallo 1971). A recent review in this book series (Reynolds 1971) has covered the problems of analysis in the presence of pesticide residues and this aspect will not be covered here. This review will be concerned with the levels found in the environment and an evaluation of toxicological and physiological effects.

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References

  • Acker, L., and E. Schulte: Occurrence of chlorinated biphenyls and hexachlorobenzene together with chlorinated insecticides in human milk and adipose tissue. Naturwissenschaften 57, 497 (1970).

    Article  PubMed  CAS  Google Scholar 

  • Ahling, B., and S. Jensen: Reversed liquid-liquid partition in determination of polychlorinated biphenyl (PCB) and chlorinated pesticides in water. Anal. Chem. 42, 1483 (1970).

    Article  PubMed  CAS  Google Scholar 

  • Anderson, D. W., J. J. Hickey, R. W. Risebrough, D. F. Hughes, and R E Christen Sen: Significance of chlorinated hydrocarbon residues to breeding pelicans and cormorants. Can. Field Naturalist 83, 89 (1969).

    Google Scholar 

  • Anonymous: Report of a new chemical hazard. New Sci. 32, 612 (1966).

    Google Scholar 

  • Bagley, G. E., W. L. Reichel, and E. Cromartie: Identification of polychlorinated bi-phenyls in two bald eagles by combined gas-liquid chromatography-mass spectrometry. J. Assoc. official Anal. Chemists 53, 251 (1970).

    CAS  Google Scholar 

  • Bauer, a, B. Schultz, and U. Spiegelberg: Berufliche Vergiftungen bei der Herstellung von Chlorphenol-Verbindungen. Arch. Gewerbepath. Gewerbehyg. 18, 538 (1961).

    Google Scholar 

  • Bennett, G. A., C. K. Drinker, and M. F. Warren: Morphological changes in the livers of rats resulting from exposure to certain chlorinated hydrocarbons. J. Ind. Hyg. Toxicol. 20, 97 (1938).

    CAS  Google Scholar 

  • Brnos, F. J., M. C. Walker, and A. Medberg: Polychlorinated biphenyls in human adipose tissue. Bull. Environ. Contam. Toxicol. 5, 317 (1970).

    Google Scholar 

  • Bitian, J., and H. C. Cecil: Estrogenic activity of DDT analogs and polychlorinated biphenyls. J. Agr. Food Chem. 18, 1108 (1970).

    Article  Google Scholar 

  • Clegg, D. J.: Embryotoxicity of chemical contaminants of foods. Food Cosmetic Toxicol. 9, 195 (1971).

    Article  CAS  Google Scholar 

  • Conney, A. H.: Pharmocological implications of microsomal enzyme induction. Pharm. Reviews 19, 317 (1967).

    CAS  Google Scholar 

  • Dahlgren, R. B., and R. L. Linder: Effects of polychlorinated biphenyls on pheasant reproduction, behavior and survival. J. Wildlife Management 35, 315 (1971).

    Article  CAS  Google Scholar 

  • Bury, R. L. Linder, and R. F. Reidinger, JR.: Residue levels and histopathology in pheasants given polychlorinated biphenyls. J. Wildlife Management 36 (in press) (1972).

    Google Scholar 

  • Duke, T. W., J. I. Lowe, and A. J. Wilson, JR.: A polychlorinated biphenyl (Aroclor 1254) in the water, sediment, and biota of Escambia Bay, Florida. Bull. Environ. Contam. Toxicol. 5, 171 (1970).

    Article  CAS  Google Scholar 

  • Flick, D. F., R. G. O’dell, and V. A. Childs: Studies of the chick edema disease. 3. Similarity of symptoms produced by feeding chlorinated biphenyl. Poultry Sci. 44, 1460 (1965).

    Article  CAS  Google Scholar 

  • Friend, M., and D. O. Trainer: Polychlorinated biphenyl: Interaction with duck hepatitis virus. Science 170, 1314 (1970).

    Article  PubMed  CAS  Google Scholar 

  • Goto, M., and K. Higuchi: The symptomatology of Yusho (chlorobiphenyls poisoning) in dermatology. Fukuoka Acta Medica 60, 7 (1969).

    Google Scholar 

  • Grant, D. L., W. E. J. Phillips, and D. C. Villeneuve: Metabolism of a polychlorinated biphenyl (Aroclor 1254) in the rat. Bull. Environ. Contam. Toxicol. 6, 102 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Hansen, D. J., P. R. Parrish, J. I. Lowe, A. J. Wilson, JR., and P. D. Wilson: Chronic toxicity, uptake, and retention of Aroclor 1254 in two estuarine fishes. Bull. Environ. Contam. Toxicol. 6, 113 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Hays, H., and R. W. Risebrough: Pollutant concentrations in abnormal chickens in a colony of terns, Sterna hirundo and Sterna dougallii on Great Gull Island in Long Island Sound. Auk 89, 19 (1972).

    Article  Google Scholar 

  • Heath, R. G., J. W. Spann, J. F. Kreitzer, and C. Vance: Effects of polychlorinated bi-phenyls on birds. XV Congress Internat. Omithol., Den Haag, Sept. 1970 (1972).

    Google Scholar 

  • Henderson, C., A. Inglis, and W. L. Johnson: Organochlorine insecticide residues in fish — Fall 1969 National Pesticide Monitoring Program. Pest. Moisit. J. 5, 1 (1971).

    CAS  Google Scholar 

  • Higginbotham, G. R., A. Huang, D. Firestone, J. Verrett, J. Ross, and A D Camp- Bell: Chemical and toxicological evaluations of isolated and synthetic chloro derivatives of dibenzo-p-dioxin. Nature 220, 702 (1968).

    Article  PubMed  CAS  Google Scholar 

  • Holden, A. V: International cooperative study of organocllorine pesticide residues in terrestrial an aquatic wildlife 1967/68. Pest Monit. J. 4, 117 (1970 a).

    Google Scholar 

  • Holden, A. V: , Source of polydilorinated biphenyl contamination in the marine environment. Nature 228, 1220 (1970 b).

    Google Scholar 

  • Holdgate, M. W. (ed.): The Seabird wreck of 1969 in thz Irish Sea. Report, Natural Environmental Research Council (1969).

    Google Scholar 

  • Hutzrn:Ger, O., S. Safe, and V. Zitzo: Polychlorinated biphenyls: Synthesis of some individual chlorobiphenyls. Bull. Environ. Contam. Toxicol. 6, 209 (1971).

    Google Scholar 

  • Jensen, J., A. G. Johnels, S. Olsson, and G. Otterlind: DDT and PCB in marine animals from Swedish waters. Nature 224, 247 (1969).

    Article  PubMed  CAS  Google Scholar 

  • Karlog, O., I. Kraul, and S. Dalgaard-Mikkelsen: Residues of polychlorinated biphenyls (PCB) and organocchlorine insecticides in liver tissue from terrestrial Danish predatory birds. Acta Vet. Scandinavica 12, 310 (1971).

    CAS  Google Scholar 

  • Kan, J. E., L. E. Priester, and S. H. Sandifer: Polychlorinated biphenyl (Aroclor 1242): Effects of uptake on growth, nucleic acids, and chlorophyll of a marine diatom. Bull. Environ. Contam. Toxicol. 6, 156 (1971).

    Article  Google Scholar 

  • Koch, R. B.: Chlorinated hydrocarbon insecticides: Inhibition of rabbit brain ATPase activities. J. Neurochem. 16, 269 (1969).

    Article  PubMed  CAS  Google Scholar 

  • Koeman, J. H., M. C. Ten Noever DE Brauw, and R. H. DE Vos: Chlorinated biphenyls in fish, mussels and birds from the River Rhine and the Netherlands coastal area. Nature 221, 1126 (1969).

    Article  PubMed  CAS  Google Scholar 

  • Lichtenstein, E. P., K. R. Schulz, T. W. Fuhremann, and T. T. Liang: Biological inter- action between plasticizers and insecticides. J. Econ. Entomol. 62, 761 (1969).

    CAS  Google Scholar 

  • Linger, J. L., and D. B. Peakall: Metabolic effects of polychlorinated biphenyls in the American kestrel. Nature 228, 738 (1970).

    Article  Google Scholar 

  • Linger, J. L., and D. B. Peakall: PCB pharmacodynamics in the Ring Dove and early gas chromatographic peak diminution. Environ. Pollut. (in press, 1972).

    Google Scholar 

  • Matsumura, P., and K. C. Patil: Adenosine triphosphatase: Sensitive to DDT in synapses of rat brain. Science 166, 121 (1969).

    Article  PubMed  CAS  Google Scholar 

  • Mccune, E. L., J. E. Savage, and B. L. O’dell: Hydropericardium and ascites in chicks fed a chlorinated hydrocarbon. Poultry Sci. 41, 295 (1962).

    Article  Google Scholar 

  • Miller, J. W.: Pathologic changes in animals exposed to a commercial chlorinated diphenyl. U. S. Public Health Record 59, 1085 (1944).

    Article  CAS  Google Scholar 

  • Monsanto. C.: Aroclor Plasticizers 59, 1085 (1944).

    Google Scholar 

  • Linger, J. L., and D. B. Peakall:Aroclor resins and plasticizers for chlorinated rubber. Tech. Bull. 0/PL-311A.

    Google Scholar 

  • Linger, J. L., and D. B. Peakall: The Aroclor polychlorinated polyphenyls. Tech. Bull. O-FF/1.

    Google Scholar 

  • Linger, J. L., and D. B. Peakall:Two-year chronic oral toxicity study of Aroclor 1242 in albino rats. IBT No. B7298 (1970 a).

    Google Scholar 

  • Linger, J. L., and D. B. Peakall:Two-year chronic oral toxicity study of Aroclor 1254 in albino rats. IBT No. B7298 (1970 b).

    Google Scholar 

  • Linger, J. L., and D. B. Peakall:Three-generation reproduction study in albino rats — Aroclor 1254. IBT No. P7297 (1970 c).

    Google Scholar 

  • Moriarty, F.: The effects of polydhlorobiphenyls on Corthippus brunneus (Saltatoria; Acrididae). Entomol. Expt.. Applied 12, 206 (1969).

    CAS  Google Scholar 

  • Nimmo, D. R., P. D. Wilson, R. R. Blackman, and A. J. Wilson, Ja.: Polychlorinated biphenyl absorbed from sediments by fiddler crabs and pink shrimp. Nature 231, 50 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Peakall, D. B.: Effect of polychlorinated biphenyls on the egg-shells of ring doves. Bull. Environ. Contam. Toxicol. 6, 100 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Linger, J. L., and D. B. Peakall:, and J. L. Linger: Polychlorinated biphenyls: Another longlife widespread chemical in the environment. BioScience 20, 958 (1970).

    Google Scholar 

  • Linger, J. L., and D. B. Peakall:, and S. E. Bloom: Embryonic mortality and dsromosomal alterations caused by Aroclor 1254 in Ring Doves. Environ. Health Perspec (in press, 1972 ).

    Google Scholar 

  • Penning, C. H.: Physicalcharacteristics and commercial possibilities of chlorinated di-phenyl. Ind. Eng. Chem 22, 1180 (1930).

    Article  CAS  Google Scholar 

  • Pichirallo, J.: Pcb’s leaks of toxic substances raises issue of effects, regulation. Science 173, 899 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Presst, I., and D. J. Jefferies• Winter numbers, breeding success, and organochlorine residues in the Great Crested Grebe in Britain. Bird Study 16, 168 (1969).

    Article  Google Scholar 

  • Linger, J. L., and D. B. Peakall:, and N. W. Moore: Polychlorinated biphenyls in wild birds in Britain and their avian toxicity. Environ. Pollution 1, 3 (1970).

    Google Scholar 

  • Rehfeld, B. M., R. L. Bradley, Jeanand M. L. Sunde: Toxicity studies on polychlorinated biphenyls in the chick. Poultry Sci. 50, 1090 (1971).

    Article  CAS  Google Scholar 

  • Reynolds, L. M.: Pesticide residue analysis in the presence of polychlorobiphenyls (PCB’s). Residue Reviews 34, 21 (1971).

    Google Scholar 

  • Risebrough, R. W.: Chlorinated hydrocarbons in the global ecosystem. In: G. G. Berg and M. W. Miller (eds.): Chemical fallout, pp. 5–23. Springfield, Ill.: C. C Thomas (1969).

    Google Scholar 

  • Linger, J. L., and D. B. Peakall:, P. Reiche, D. B. Peakall, S. G. Herman, and M. N. Kirven: Polychlorinated biphenyls in the global ecosystem. Nature 220, 1098 (1968).

    Google Scholar 

  • Linger, J. L., and D. B. Peakall:, G. L. Florant, and D. D. Berger: Organochlorine pollutants in Peregrines and Merlins migrating through Wisconsin. Can. Field-Naturalist 84, 247 (1970).

    Google Scholar 

  • Robinson, J.: Persistent pesticides. Ann. Rev. Pharmacol. 10, 353 (1970).

    Article  PubMed  CAS  Google Scholar 

  • Schmidt, T. T., R. W. Risebrough, and F. Gress: Urban sewage outfalls. Bull. Environ. Contam. Toxicol. 6, 235 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Scott, M. L., D. V. Vadehra, P. A. Mullenhoff, G. L. Rumsey, and R. W. Rice: Results of experiments on the effects of PCB’s on laying hen performance. Proc. Cornell Nutrition Conf., p. 56, (1971).

    Google Scholar 

  • Stickel, L. F., W. H. Stickel, and R. Christensen: Residues of DDT in brains and bodies of birds that died on dosage and in survivors. Science 151, 1549 (1969).

    Article  Google Scholar 

  • Street, J. C., F. M. Urry, D. J. W.Agstaff, and A. D. Blau: Comparative effects of poly-. chlorinated biphenyls and organochlorine pesticide in induction of hepatic microsomal enzyme. Presented Amer. Chem. Soc. meeting, Sept. 8–12, New York (1969).

    Google Scholar 

  • Tanaka, K., S. Fujita, F. Komatsu, and N. Tamura: Experimental subacute poisoning of dnlorobiphenyls, particularly the influence on the serum lipids in rats. Fukuoka Acta Medica 60, 142 (1969).

    Google Scholar 

  • Tarrant, K. R., and J. O’G. Tatton: Organochlorine pesticides in rainwater in the British Isles. Nature 219, 725 (1968).

    Article  PubMed  CAS  Google Scholar 

  • Tucker, R. K., and D. G. Crabtree: Handbook of toxicity of pesticides to wildlife. U. S. Deparment of Interior, Resource Pub. No. 84 (1970).

    Google Scholar 

  • Ulfstrand, S., A. Sodergren, and J. Rabol: Effect of PCB on nocturnal activity in caged robins, Erithacus rubecula L. Nature 231, 467 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Vermeer, K., and L. M. Reynolds: Organochlorine residues in aquatic birds in the Canadian Prairie Provinces. Can. Field-Naturalist 84, 117 (1970).

    Google Scholar 

  • Villeneuve, D. C., D. L. Grant, W. E. J. Phillips, M. L. Clark, and D. J. Clegg: Effects of PCB administration on microsomal enzyme activity in pregnant rabbits. Bull. Environ. Contam. Toxicol. 6, 120 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Vos, J. G., and J. H. Koeman: Comparative toxicological study with polychlorinated bi-phenyls in chickens with special reference to porphyria, edema formation, liver necrisis and tissue residues. Toxicol. Applied Pharmacol. 17, 656 (1970).

    Article  CAS  Google Scholar 

  • Linger, J. L., and D. B. Peakall:, H. L. Van Der Maas, M. C. Ten Noever De Brauw, and R. H. DE Vos: Identification and toxicological evaluation of chlorinated bibenzofuran and chlorinated napthalene in two commercial polydllorinated biphenyls. Food Cosmetic Toxicol. 8, 625 (1970).

    Google Scholar 

  • Wildish, D. J.: The toxicity of PCB in sea water to Gammarus oceanicus. Bull. Environ. Contam. Toxicol. 5, 202 (1970).

    Article  CAS  Google Scholar 

  • Yamaguchi, A., T. Yosssmmra, and M. Kuratsune: A survey on pregnant women having consumed rice oil contaminated with chlorobiphenyls and their babies. Fukuoka Acta Medica 62, 117 (1971).

    Google Scholar 

  • Yap, H. H.: Sensitivity of fish ATPases to PCB. Nature 233, 61 (1971).

    Article  PubMed  CAS  Google Scholar 

  • ZiktoTO, V.: Polychlorinated biphenyls and organochlorine pesticides in some freshwater and marine fish. Bull. Environ. ontam. Toxicol. 6, 464 (1971).

    Article  Google Scholar 

  • Yap, H. H.: Manuscript received December 3, 1971; accepted February 15, 1972.

    Google Scholar 

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Peakall, D.B. (1972). Polychlorinated biphenyls: Occurrence and biological effects. In: Gunther, F.A., Gunther, J.D. (eds) Residue Reviews. Residue Reviews, vol 44. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-8491-9_1

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