Trace Elements

  • Chapter
Nutrition and the Adult

Part of the book series: Human Nutrition ((HUNU,volume 3B))

Abstract

Mineral elements generally have two functions in the body: structural, which affects the skeleton and soft tissues, and regulatory, which involves a wide array of physiological functions such as clotting of blood, neuromuscular transmission, oxygen transport, and catalysis and regulation of enzymes.

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References

  • Addison, W. L., 1928, The use of sodium chloride, potassium chloride, sodium bromide, potassium bromide in cases of arterial hypertension which are amenable to potassium chloride, Can. Med. Assoc. J. 18: 281.

    CAS  Google Scholar 

  • Agarwal, B. N., and Agarwal, P., 1976, Magnesium deficiency in clinical medicine: A review, J. Am. Med. Women’s Assoc. 31: 72.

    CAS  Google Scholar 

  • Aikawa, J. K., 1976, Biochemistry and physiology of magnesium, in: Trace Elements in Human Health and Disease, Vol. II ( A. S. Prasad and D. Oberleas, eds.), pp. 47–78, Academic Press, New York.

    Google Scholar 

  • Alexander, C. S. A., 1969, Cobalt and the heart, Ann. Intern. Med. 70: 411.

    CAS  Google Scholar 

  • Ambard, L., and Beaujard, E., 1904, Causes del’hypertension artérielle, Arch. Med. Gén. 1:520. Anand, C. R., and Linkswiler, H. M., 1974, Effect of protein intake on calcium balance of young men given 500 mg calcium daily, J. Nutr. 104: 695.

    Google Scholar 

  • Asling, C. W., and Hurley, L. S., 1963, The influence of trace elements on the skeleton, Clin. Orthop. 27: 213.

    CAS  Google Scholar 

  • Avioli, L. V., 1972, Intestinal absorption of calcium, Arch. Intern. Med. 129: 345.

    Article  CAS  Google Scholar 

  • Awasthi, Y. C., Beutler, E., and Srivastava, S. K., 1975, Purification and properties of human erythrocyte glutathione peroxidase, J. Biol. Chem. 250: 5144.

    CAS  Google Scholar 

  • Azarnoff, D. L., and Curran, G. L., 1957, Site of vanadium inhibition of cholesterol biosynthesis, J. Am. Chem. Soc. 79: 2968.

    Article  CAS  Google Scholar 

  • Azarnoff, D. L., Brock, F., and Curran, G. L., 1961, A specific site of vanadium inhibition of cholesterol biosynthesis, Biochim. Biophys. Acta. 51: 397.

    Article  CAS  Google Scholar 

  • Barnes, J. M., and Stoner, H. B., 1959, The toxicology of tin compounds, Pharmacol. Rev. 11: 211.

    CAS  Google Scholar 

  • Bergstrom, J., Alvestrand, A., Furst, P., Mulfman, M. E., Sahlen, K., Vinnars, E., and Widstrom, A., 1976, Influence of severe potassium depletion and subsequent repletion with potassium on muscle electrolytes, metabolites and amino acids in man, Clin. Sci. Mol. Med. 51: 589.

    CAS  Google Scholar 

  • Berle, A. B., 1974, Calcium and phosphate metabolism, Annu. Rev. Physiol. 36: 361.

    Article  Google Scholar 

  • Bernheim, F., and Bernheim, M., I939a, Note on the action of manganese and some other metals on the oxidation of certain substances by liver, J. Biol. Chem. 128: 79.

    Google Scholar 

  • Bernheim, F., and Bernheim, M., 19396, The action of vanadium on oxidation of phospholipid by certain tissues, J. Biol. Chem. 127: 353.

    Google Scholar 

  • Bernstein, D. S., Sadowsky, N., Hegsted, D. M., Guri, C. S., and Stare, F. J., 1966, Prevalence of osteporosis in high and low fluoride areas in North Dakota, J. Am. Med. Assoc. 198: 499.

    Article  CAS  Google Scholar 

  • Bjorn-Rasmussen, E., Hallsberg, L., Isaksson, B., and Arvidsson, B., 1974, Food iron absorption in man. Applications of the two pool extrinsic tag method to measure heme and nonheme iron absorption from the whole set, J. Clin. Invest. 53: 247.

    Article  CAS  Google Scholar 

  • Blamberg, D. L., Blackwood, V. B., Supplee, W. C., and Combs, G. F., 1960, Effect of zinc deficiency in hens on hatchability and embryonic development, Proc. Soc. Exp. Biol. Med. 104: 217.

    CAS  Google Scholar 

  • Brimacombe, R., Nierhaus, R. H., Garrett, R. A., and Wittmann, H. G., 1976, The ribosome of E. coli, Prog. Nucleic Acid Res. Mol. Biol. 18: 1.

    Article  CAS  Google Scholar 

  • Brown, D. G., Burk, R. F., Seely, R. J., and Kikar, R. W., 1972, Effect of dietary selenium on gastrointestinal absorption of 95SeO32 in the rat, Int. J. Vitam. Nutr. Res. 42: 588.

    CAS  Google Scholar 

  • Brown, H., 1927, The mineral content of human skin, J. Biol. Chem. 75: 789.

    CAS  Google Scholar 

  • Burch, R. E., and Sullivan, J. F., 1976, Clinical and nutritional aspects of zinc deficiency and excess, Med. Clin. North Am. 60: 675.

    CAS  Google Scholar 

  • Burk, R. F., 1976, Selenium in man, in: Trace Elements in Human Health and Disease, Vol. II ( A. S. Prasad and D. Oberleas, eds.), pp. 105–134, Academic Press, New York.

    Google Scholar 

  • Carlisle, E. M., 1970a, A relation between silicon and calcium in bone formation, Fed. Proc. Fed. Am. Soc. Exp. Biol. 29: 565.

    Google Scholar 

  • Carlisle, E. M., 1970b, Silicon: A possible factor in bone calcification, Science 167:279. Carlisle, E. M., 1972, Silicon: An essential element for the chick, Science 178: 619.

    Article  Google Scholar 

  • Carlisle, E. M., 1974a, Silicon as an essential element, Fed. Proc. Fed. Am. Soc. Exp. Biol. 33: 1758.

    Google Scholar 

  • Carlisle, E. M., 1974b, A relationship between silicon, GAG, and collagen formation, Fed. Proc. Fed. Am. Soc. Exp. Biol. 33: 704.

    Google Scholar 

  • Carlisle, E. M., 1975, Silicon in the osteoblast, the bone forming cell, Fed. Proc. Fed. Am. Soc. Exp. Biol. 34: 927.

    Google Scholar 

  • Carlisle, E. M., 1976, In Tiro requirement for silicon in articular cartilage and connective tissue formation in the chick, J. Noir. 106: 478.

    CAS  Google Scholar 

  • Carlson, C. H., Armstrong, W. D., and Singer, L., 1960, Distribution and excretion of radiofluoride in the human, Proc. Soc. Exp. Biol. Med. 104: 235.

    CAS  Google Scholar 

  • Carnes, W. H., 1971, Role of copper in connective tissue metabolism, Fed. Proc. Fed. Am. Soc. Exp. Biol. 30: 995.

    CAS  Google Scholar 

  • Clayton, C. C., and Baumann, C. A., 1949, Diet and azo dye tumors: Effect of diet during a period when the dye is not fed, Cancer Res. 9: 575.

    CAS  Google Scholar 

  • Cohn, J. N., 1977, Heart disease in hypertensive patient, Med. Clin. North Am. 61: 581.

    CAS  Google Scholar 

  • Cohn, W. E., and Volkin, E. (eds.), 1976, mRNA: The Relation of Structure to Function (Prog. Nucleic Acid Res. Mol. Biol., Vol. 19 ), Academic Press, New York.

    Google Scholar 

  • Combs, G. F., Noguchi, T., and Scott, M. L., 1975, Mechanisms of action of selenium and vitamin E in protection of biological membranes, Fed. Proc. Fed. Am. Soc. Exp. Biol. 34: 2090.

    CAS  Google Scholar 

  • Composition of Foods,1963, U.S. Dep. Agric. Agric. Handb. No. 8.

    Google Scholar 

  • Cook, J. D., and Finch, C. A., 1975, Iron nutrition, West. J. Med. 122: 474.

    CAS  Google Scholar 

  • Cook, J. D., Lipschitz, D. A., Miles, L. E. M., and Finch, C. A., 1974, Serum ferritin as a measure of iron stores in normal subjects, Am. J. Clin. Nutr. 27: 681.

    CAS  Google Scholar 

  • Cook, M. A., 1969, Fluoride and tea, Lancet 2: 329.

    Article  CAS  Google Scholar 

  • Cotzias, G. C., Papvasiliou, P. S., Ginas, J., Steck, A., and Ruby, S., 1971, Metabolic modification of Parkinson’s disease and of chronic manganese poisoning, Annu. Rev. Med. 22: 305.

    Article  CAS  Google Scholar 

  • Cotzias, G. C., Tang, L. C., Miller, S. T., Ladic-Simu, D. S., and Hurley, L. S., 1972, A mutation influencing the transportation of L-dopa, L-tryptophan and manganese, Science 176: 410.

    Article  CAS  Google Scholar 

  • Cotzias, G. C., Miller, S. T., Papavasiliou, P. S., and Tang, L. C., 1976, Interactions between manganese and brain dopamine, Med. Clin. North Am. 60: 729.

    CAS  Google Scholar 

  • Crampton, R. F., Matthews, M., and Poisner, R., 1965, Observations on the mechanism of absorption of copper by the small intestine, J. Physiol. 118: 111.

    Google Scholar 

  • Curran, G. L., 1954, Effect of certain transition group elements on hepatic synthesis of cholesterol in the rat, J. Biol. Chem. 210: 765.

    CAS  Google Scholar 

  • Curran, G. L., and Burch, R. E., 1967, Biological and health effects of vanadium, in: Proceedings of the University of Missouri 1st Annual Conference on Trace Substances in Environmental Health ( D. D. Hemphill, ed.), pp. 96–104, University of Missouri Press, Columbia.

    Google Scholar 

  • Curran, G. L., and Costello, R. L., 1956, Reduction of excess of cholesterol in the rabbit aorta by inhibition of endogenous cholesterol synthesis, J. Exp. Med. 103: 49.

    Article  CAS  Google Scholar 

  • Curran, G. L., Azarnoff, D. L., and Bolinger, R. E., 1959, Effect of cholesterol synthesis inhibition in normocholesteremic young men, J. Clin. Invest. 38: 1251.

    Article  CAS  Google Scholar 

  • Dahl, L. K., 1958, Salt intake and salt need, N. Engl. J. Med. 258: 1152.

    Google Scholar 

  • Dahl, L. K., 1960, Effects of chronic excess salt feeding: Elevation of plasma cholesterol in rats and dogs, J. Exp. Med. 112: 635.

    Article  CAS  Google Scholar 

  • Dahl, L. K., 1968, Salt in processed baby foods, Am. J. Clin. Nutr. 21: 787.

    CAS  Google Scholar 

  • Dahl, L. K., 1972, Salt and hypertension, Am. J. Clin. Nutr. 25: 231.

    CAS  Google Scholar 

  • Dahl, L. K., and Love, R. A., 1957, Etiological role of sodium chloride intake in essential hypertension in humans, J. Am. Med. Assoc. 164: 397.

    Article  CAS  Google Scholar 

  • Dahl, L. K., Knudsen, K. D., Meine, M. A., and Leitl, G. J., 1968, Effects of chronic excess salt ingestion. Modification of experimental hypertension in the rat by variations in the diet, Circ. Res. 22: 11.

    CAS  Google Scholar 

  • Dahl, L. K., Leitl, G., and Heine, M., 1972, Influence of dietary potassium and sodium/potassium molar ratios on the development of salt hypertension, J. Exp. Med. 136: 318.

    Article  CAS  Google Scholar 

  • D’Alonzo, C. A., and Pell, S., 1963, A study of trace metals in myocardial infarction, Arch. Environ. Health 6: 381.

    Google Scholar 

  • Davidson, I. W. F., and Blackwell, W. L., 1968, Changes in carbohydrate metabolism of squirrel

    Google Scholar 

  • monkeys with chromium dietary supplementation, Proc. Soc. Exp. Biol. Med. 127:66.

    Google Scholar 

  • DeLuca, H. F., and Schnoes, H. K., 1976, Metabolism and mechanism of action of vitamin D, Annu. Rev. Biochem. 45: 631.

    Article  CAS  Google Scholar 

  • Dimond, G., Caravaca, J., and Benchimol, A., 1963, Vanadium: Excretion toxicity lipid effect in man, Am. J. Clin. Nutr. 12: 49.

    CAS  Google Scholar 

  • Doisy, R. J., Streeten, D. H. P., Schneider, A. J., and Freiberg, J. M., 1976, Chromium in man and biochemical effects, in: Trace Elements in Human Health and Disease, Vol. II ( A. S. Prasad and D. Oberleas, eds.), pp. 79–104, Academic Press, New York.

    Google Scholar 

  • Duckworth, J., and Warnock, G. M., 1942–1943, The magnesium requirement of man in relation to calcium requirements with observations on the adequacy of diets in common use, Nutr. Abstr. Rev. 12: 167.

    Google Scholar 

  • Efstratiadis, A., Kafatos, F. C., and Maniatis, T., 1977, The primary structure of rabbit ß globin mRNA as determined from cloned DNA, Cell 10: 571.

    Article  CAS  Google Scholar 

  • Erway, L., Hurley, L. S., and Fraser, A., 1970, Congenital ataxia and otolith defects due to manganese deficiency in mice, J. Nutr. 100: 643.

    CAS  Google Scholar 

  • Erway, L., Fraser, A., and Hurley, L. S., 1971, Prevention of congenital otolith defect in Pallid mutant mice by manganese supplementation, Genetics 67: 97.

    CAS  Google Scholar 

  • Evans, G. W., 1973, Copper homeostasis in the mammalian system, Physiol. Rev. 53: 535.

    CAS  Google Scholar 

  • Evans, G. W., 1976, Zinc absorption and transport, in: Trace Elements in Human Health and

    Google Scholar 

  • Disease,Vol. I (A. S. Prasad and D. Oberleas, eds.), pp. 181–188, Academic Press, New York.

    Google Scholar 

  • Evans, G. W., Mojas, P. F., and Cornatzer, W. E., 1970, Ascorbic acid interaction of metallo hionein, Biochem. Biophys. Res. Commun. 41: 1244.

    Article  CAS  Google Scholar 

  • Everson, G. J., and Shrader, R. E., 1968, Abnormal glucose tolerance in manganese deficient guinea pigs, J. Nutr. 94: 89.

    CAS  Google Scholar 

  • Fairhall, L. T., and Hoyt, L. M., 1929, The excretion of zinc in health and disease, J. Clin. Invest. 7: 537.

    Article  CAS  Google Scholar 

  • Filmer, J. F., and Underwood, E. J., 1937, Enzootic marasmus: Further data concerning the potency of cobalt as a curative and prophylactic agent, Aust. Vet. J. 13:57.

    Google Scholar 

  • Finch, C. A., 1976, Iron metabolism, in: Nutrition Reviews’ Present Knowledge in Nutrition, pp. 280–289, Nutrition Foundation, Washington, D.C.

    Google Scholar 

  • Finch, C. A., Deubelbeiss, K., Cook, J. D., Eschbach, J. W., Marker, L. A., Funk, D. D., Marsaglia, G., Hillman, R. S., Slichter, S., Adamson, J. W., Ganzoni, A., and Gilbert, E. R., 1970, Ferrokinetics in man, Medicine (Baltimore) 49: 17.

    CAS  Google Scholar 

  • Flink, E. B., 1976, Magnesium deficiency and magnesium toxicity in man, in: Trace Elements in Human Health and Disease, Vol. II ( A. S. Prasad and D. Oberleas, eds.), pp. 1–22, Academic Press, New York.

    Google Scholar 

  • Fridovich, I., 1975, Superoxide dismutases, Annu. Rev. Biochem. 44: 147.

    Article  CAS  Google Scholar 

  • Frieden, E., and Hsich, M. S. T., 1976, Ceruloplasmin: The copper transport protein of essential oxidase activity, Adv. Enz.ymol. 44: 187.

    CAS  Google Scholar 

  • Friedman, M. (ed.), 1974, Protein-Metal Interactions (Adv. Exp. Med. Biol., Vol. 48 ), Plenum Press, New York.

    Google Scholar 

  • Frost, D. V., and Lish, P. M., 1975, Selenium in biology, Annu. Rev. Pharmacol. Toxicot. 15: 259.

    Article  CAS  Google Scholar 

  • Fuller, H. L., and Leach, R. M., 1975, Biochemical function of selenium and its interrelationships with other trace elements and vitamin E, Fed. Proc. Fed. Am. Soc. Exp. Biol. 34: 2082.

    Google Scholar 

  • Ganther, M. E., Hafeman, D. G., Lawrence, R. A., Serfass, R. E., and Hoekstra, W. G., 1976, Selenium and gluathione peroxidase in health and disease: A review, in: Trace Elements in Human Health and Disease, Vol. II ( A. S. Prasad and D. Oberleas, eds.), pp. 165–234, Academic Press, New York.

    Google Scholar 

  • Glinsmann, W. H., and Mertz, W., 1966, Effect of trivalent chromium on glucose tolerance, Metab. Clin. Exp. 15: 510.

    Article  CAS  Google Scholar 

  • Grinvalsky, M. T., and Fitch, D. M., 1969, A distinctive myocardiopathy occurring in Omaha, Nebraska: Pathological aspects, Ann. N.Y. Acad. Sci. 156: 544.

    Article  CAS  Google Scholar 

  • Hafez, Y., and Kratzer, F. M., 1976, The effect of dietary vanadium on fatty acid and cholesterol synthesis and turnover in the chick, J. Nutr. 106: 249.

    CAS  Google Scholar 

  • Halsted, J. A., and Prasad, A. S., 1960, Syndrome of iron deficiency anemia, hepatosplenomegaly

    Google Scholar 

  • hypogonadism, dwarfism and geophagia, Trans. Am. Clin. Climatol. Assoc. 72:130. Halsted, J. A., and Smith, J. C., 1970, Plasma-zinc in health and disease, Lancet 1:322.

    Google Scholar 

  • Halsted, J. A., and Smith, J. C., and Irwin, M. J., 1974, A conspectus of research on zinc requirement of man, J. Nutr. 104: 345.

    CAS  Google Scholar 

  • Hambidge, K. M., 1974, Chromium nutrition in man, Am. J. Clin. Nutr. 27: 505.

    CAS  Google Scholar 

  • Harris, E. D., Rayton, J. K., and DeGroot, J. E., 1977, A critical role for copper in aortic elastin structure and synthesis, Adv. Exp. Med. Biol. 79: 543.

    CAS  Google Scholar 

  • Harrison, H. E., 1976, Phosphorus, in: Nutrition Reviews’ Present Knowledge in Nutrition, pp. 241–246, Nutrition Foundation, Washington, D.C.

    Google Scholar 

  • Hart, E. B., Steinbock, H. B., Waddell, J., and Elvehjem, C. A., 1928, Iron in nutrition. VII. Copper as a supplement to iron for hemoglobin building in the rat, J. Biot Chem. 77: 797.

    CAS  Google Scholar 

  • Hegsted, D. M., 1973, Major minerals: Calcium and phosphorus, in: Modern Nutrition in Health and Disease ( R. S. Goodhart and M. Shils, eds.), pp. 268–286, Lea and Febiger, Philadelphia.

    Google Scholar 

  • Henkin, R. I., 1971, Idiopathic hypogeusia with dysgeusia, hyposmia, and dysosmia, J. Am. Med. Assoc. 217: 434.

    Article  CAS  Google Scholar 

  • Henkin, R. I., and Bradley, D. F., 1970, Hypogeusia corrected by nickel and zinc, Life Sci. 9: 701.

    Article  CAS  Google Scholar 

  • Hill, C. H., 1975, Interrelationship of selenium with other trace elements, Fed. Proc. Fed. Am. Soc. Exp. Biol. 34: 2096.

    CAS  Google Scholar 

  • Hodge, M. C., and Smith, F. A., 1968, Fluorides and man, Annu. Rev. Pharmacol. 8: 395.

    Article  CAS  Google Scholar 

  • Hoekstra, W. G., 1975, Biochemical function of selenium and its relation to vitamin E, Fed. Proc. Fed. Am. Soc. Exp. Biol. 34: 2083.

    CAS  Google Scholar 

  • Holtzmann, N. A., 1976, Menke’s kinky hair syndrome: A genetic disease involving copper, Fed. Proc. Fed. Am. Soc. Exp. Biol. 35: 2276.

    Google Scholar 

  • Holwerda, R. A., Wherland, S., and Gray, H. B., 1976, Electron transfer of copper proteins, Annu. Rev. Biophys. Bioeng. 5: 363.

    Article  CAS  Google Scholar 

  • Hopkins, L. L., and Mohr, M. E., 1971a, Effect of vanadium deficiency on plasma cholesterol of chicks, Fed. Proc. Fed. Am. Soc. Exp. Biol. 30: 462.

    Google Scholar 

  • Hopkins, L. L., and Mohr, M. E., 1971b, The biological essentiality of vanadium, in: Newer Trace Elements in Nutrition ( W. Mertz and W. E. Cornatzer, eds.), pp. 195–214, Marcel Dekker, New York.

    Google Scholar 

  • Hopkins, L. L., and Mohr, M. E., 1974, Vanadium as an essential nutrient, Fed. Proc. Fed. Am. Soc. Exp. Biol. 33: 1773.

    Google Scholar 

  • Hunt, C. E., Landesman, E. J., and Newberne, P. M., 1970, Copper deficiency in chicks: Effects of ascorbic acid on iron, copper, cytochrome oxidase activity and aortic mucopolysaccharides, Br. J. Nutr. 24: 607.

    Article  CAS  Google Scholar 

  • Hurley, L. S., 1976a, Manganese and other trace elements, in: Nutrition Reviews’ Present Knowledge in Nutrition, pp. 345–355, Nutrition Foundation, Washington, D.C.

    Google Scholar 

  • Hurley, L. S., 1976b, Interaction of genes and metals in development, Fed. Proc. Fed. Am. Soc. Exp. Biol. 35: 2271.

    CAS  Google Scholar 

  • Hurley, L. S., and Swenerton, H., 1966, Congenital malformations resulting from zinc deficiency in rats, Proc. Soc. Exp. Biol. Med. 123: 692.

    CAS  Google Scholar 

  • Hurley, L. S., Duncan, J. R., Sloan, M. V., and Eckert, C. D., 1977, Zinc binding ligands in milk and intestine: A role in neonatal nutrition, Proc. Natl. Acad. Sci. U.S.A. 74:3547. Intersociety Commission for Heart Diseases Resources, 1971, Report of Intersociety Commission for Heart Diseases Resources, Circulation 44: A237.

    Google Scholar 

  • Irwin, M. I., and Kienholz, E. W., 1973, A conspectus of research on calcium requirements of man, J. Nutr. 103: 1019.

    CAS  Google Scholar 

  • Isaacson, L. C., Modlin, M., and Jackson, W. P. U., 1963, Sodium intake and hypertension, Lancet 1: 946.

    Article  CAS  Google Scholar 

  • Johnson, N. E., Alcantara, E. N., and Linkswiler, H., 1970, Effect of level of protein intake on urinary and fecal calcium and calcium retention of young adult males, J. Nutr. 100: 1425.

    CAS  Google Scholar 

  • Jorgensen, P. L., 1975, Isolation and characterization of the components of sodium pump, Q. Rev. Biophys. 7: 239.

    Article  Google Scholar 

  • Jowsey, J., Riggs, B. L., Kelley, P. J., and Hoffman, D. L., 1972, Effect of combined therapy with sodium fluoride, vitamin D and calcium in osteoporosis, Am. J. Med. 53: 43.

    Google Scholar 

  • Kagan, A., Kannel, W. B., Dawber, T. R., and Revotskie, N., 1962, The coronary profile, Ann. N.Y. Acad. Sci. 94: 883.

    Google Scholar 

  • Kappas, A., and Maines, M. D., 1976, Tin: A potent inducer of heme oxygenase in kidney, Science 192: 60.

    Article  CAS  Google Scholar 

  • Kehoe, R. A., Cholok, J., and Story, R. V., 1940, A spectrochemical study of the normal ranges of concentration of certain trace metals in biological materials, J. Nutr. 19: 579.

    CAS  Google Scholar 

  • Keilin, D., and Mann, T., 1939, Carbonic anhydrase, Nature 144: 442.

    Article  CAS  Google Scholar 

  • Keilin, D., and Mann, T., 1940, Carbonic anhydrase: Purification and nature of the enzyme, Biochem. J. 34: 1163.

    CAS  Google Scholar 

  • Kempner, W., 1944, Treatment of kidney disease and hypertensive vascular disease with rice diet, N. C. Med. J. 5: 125.

    Google Scholar 

  • Kempner, W., 1948, Treatment of hypertensive vascular disease with rice diet, Am. J. Med. 4: 545.

    Article  CAS  Google Scholar 

  • Kirchgessner, M., and Grassman, E., 1970, The dynamics of copper absorption, in: Trace Element Metabolism ( C. F. Mills, ed.), pp. 277–287, Livingstone, Edinburgh.

    Google Scholar 

  • Klevay, L. M., 1975, Coronary heart disease: The zinc/copper hypothesis, Am. J. Clin. Nutr. 28: 764.

    CAS  Google Scholar 

  • Koletsky, S., 1961, Pathogenesis of experimental hypertension induced by salt, Am. J. Cardiol. 8: 576.

    Article  CAS  Google Scholar 

  • Kramer, L., Osis, D., Wratrowski, E., and Spencer, H., 1974, Dietary fluoride in different areas in the United States, Am. J. Clin. Nutr. 27: 590.

    CAS  Google Scholar 

  • Kreisberg, R. A., 1977, Phosphorus deficiency and hypophosphatemia, Hosp. Prac. 12: 121.

    CAS  Google Scholar 

  • Kretsinger, R. H., 1976, Calcium-binding proteins, Annu. Rev. Biochem. 45: 239.

    Article  CAS  Google Scholar 

  • Layrisse, M., Martinez-Torres, C., and Gonzales, M., 1974, Measurement of the total daily dietary iron absorption by the extrinsic tag model, Am. J. Clin. Nutr. 27: 152.

    CAS  Google Scholar 

  • Leach, R. M., 1971, Role of manganese in mucopolysaccharide metabolism, Fed. Proc. Fed. Am. Soc. Exp. Biol. 30: 991.

    CAS  Google Scholar 

  • Leach, R. M., 1976, Metabolism and function of manganese, in: Trace Elements in Human Health and Disease, Vol. II ( A. S. Prasad and D. Oberleas, eds.), pp. 235–247, Academic Press, New York.

    Google Scholar 

  • Lee, G. R., Williams, D. M., and Cartwright, G. E., 1976, Role of copper in iron metabolism and heure biosynthesis, in: Trace Elements in Human Health and Disease, Vol. I ( A. S. Prasad and D. Oberleas, eds.), pp. 373–390, Academic Press, New York.

    Google Scholar 

  • Levander, O. A., Morris, V. C., and Higgs, D. J., 1973, Acceleration of thiol induced swelling of rat liver mitochondria by selenium, Biochemistry 12: 4586.

    Article  CAS  Google Scholar 

  • Levine, R. A., Streeten, D. H. P., and Doisy, R. J., 1968, Effects of oral chromium supplementation on glucose tolerance of elderly human subjects, Metab. Clin. Exp. 17: 114.

    Article  CAS  Google Scholar 

  • Lewis, C. E., 1959, The biological action of vanadium: I. Effects upon serum cholesterol levels in man, AMA Arch. Ind. Health 19: 419.

    CAS  Google Scholar 

  • Lindquist, R. R., 1968, Studies on the pathogenesis of hepatolenticular degeneration. III. The effect of copper on rat liver lysosomes, Am. J. Pathol. 53: 903.

    CAS  Google Scholar 

  • Linkswiler, H. M., Joyce, C. T. L., and Anand, C. R., 1974, Calcium retention of young adult males as affected by level of protein and of calcium intake, Trans. N.Y. Acad. Sci. 36: 333.

    CAS  Google Scholar 

  • Loeper, J., Loeper, J., and Lemaire, A., 1966, Étude du silicium en biologie animale et au cours de l’athérome, Presse Méd. 74: 865.

    CAS  Google Scholar 

  • Lotz, M., Zisman, E., and Bartter, F. C., 1968, Evidence for a phosphorus depletion syndrome in man, N. Engl. J. Med. 278: 409.

    Article  CAS  Google Scholar 

  • Maines, M. D., and Kappas, A., 1975, Cobalt stimulation of heme degradation in the liver. Dissociation of microsomal oxidation of heme from cytochrome P450, J. Biol. Chem. 250: 4171.

    CAS  Google Scholar 

  • Maines, M. D., and Kappas, A., 1976a, Studies on the mechanism of induction of haem oxygenase by cobalt and other metal ions, Biochem. J. 154: 125.

    CAS  Google Scholar 

  • Maines, M. D., and Kappas, A., 1976b, Selenium regulation of hepatic heme metabolism induction of 8-aminolaevulinate synthase and heure oxygenase, Proc. Natl. Acad. Sci. U.S.A. 73: 4428.

    Article  CAS  Google Scholar 

  • Maines, M. D., Janousek, V., Tomio, J. M., and Kappas, A., 1976, Cobalt inhibition of synthesis and induction of 8-aminolevulinate synthase in liver, Proc. Natl. Acad. Sci. U.S.A. 73: 1499.

    Article  CAS  Google Scholar 

  • Margen, S., Chu, J.-Y., Kaufmann, N. A., and Calloway, D. H., 1974, Studies in calcium metabolism, I. The calciuretic effect of dietary protein, Am. J. Clin. Nutr. 27: 584.

    CAS  Google Scholar 

  • Margolis, F. J., Reames, M. R., Freshman, E. F., Macauley, J. C., and Mehaffey, H., 1975, Fluoride ten year prospective study of deciduous and permanent dentition, Am. J. Dis. Child. 129: 794.

    CAS  Google Scholar 

  • Massry, S. G., and Ritz, E. (eds.), 1977, Phosphate Metabolism (Advances in Experimental Medicine and Biology, Vol. 81 ), Plenum Press, New York.

    Google Scholar 

  • McCance, R. A., and Widdowson, E. M., 1942, The absorption and excretion of zinc, Biochem. J. 36: 692.

    CAS  Google Scholar 

  • McCord, J. M., 1976, Iron and manganese containing superoxide dismutase: Structure, distribution and evolutionary relationships, Adv. Exp. Med. Biol. 74: 540.

    CAS  Google Scholar 

  • McNeeley, M. D., Sunderman, F. W., Nechay, M. W., and Levine, M., 1971, Abnormal concentrations of nickel in serum in cases of myocardial infarction, stroke, burns, hepatic cirrhosis and uremia, Clin. Chem. 17: 1123.

    Google Scholar 

  • McQuarrie, I., Thompson, W. M., and Anderson, J. A., 1936, Effects of excessive ingestion of sodium and potassium salts on carbohydrate metabolism and blood pressure in diabetic children, J. Nutr. 11: 77.

    CAS  Google Scholar 

  • Meneely, G. R., and Ball, C. O. T., 1958, Experimental epidemiology of chronic sodium chloride toxicity and protective effect of potassium chloride, Am. J. Med. 25: 713.

    Article  CAS  Google Scholar 

  • Meneely, G. R., and Battarbee, M. D., 1976, Sodium and potassium, in: Nutrition Reviews’ Present Knowledge in Nutrition, pp. 259–279, Nutrition Foundation, Washington, D.C.

    Google Scholar 

  • Meneely, G. R., Tucker, R. G., Darby, W. J., and Auerbach, S. H., 1953, Chronic sodium chloride toxicity: Hypertension, renal and vascular lesions, Ann. Intern. Med. 39: 991.

    CAS  Google Scholar 

  • Meneely, G. R., Ball, C. O. T., and Youmans, J. B., 1957, Chronic sodium chloride toxicity: The protective effect of added potassium chloride, Ann. Intern. Med. 47: 263.

    CAS  Google Scholar 

  • Meneely, G. R., Lemley-Stone, J., and Darby, W. J., 1961, Changes in blood pressure and body sodium of rats fed sodium and potassium chloride, Am. J. Cardiol. 8: 527.

    Article  CAS  Google Scholar 

  • Mertz, W., 1969, Chromium occurrence and function in biological systems, Physiol. Rev. 49: 163.

    CAS  Google Scholar 

  • Mertz, W., 1976, Chromium and its relation to carbohydrate metabolism, Med. Clin. North Am. 60: 739.

    CAS  Google Scholar 

  • Mertz, W. E., Roginski, E., and Schwarz, K., 1961, Effect of trivalent chromium complexes on glucose uptake by epididymal fat tissue of rats, J. Biol. Chem. 236: 318.

    CAS  Google Scholar 

  • Mertz, W., Roginski, E. E., and Reba, R. C., 1965, Biological activity and the fate of trace quantities of intravenous chromium(III) in the rat, Am. J. Physiol. 209: 489.

    CAS  Google Scholar 

  • Mertz, W., Toepfer, E. W., and Roginski, E. E., 1974, Present knowledge of the role of chromium, Fed. Proc. Fed. Am. Soc. Exp. Biol. 33: 2275.

    CAS  Google Scholar 

  • Messer, M. M., and Singer, L., 1976, Fluoride, in: Nutrition Reviews’ Present Knowledge in Nutrition, pp. 325–336, Nutrition Foundation, Washington, D.C.

    Google Scholar 

  • Messer, M. M., Armstrong, W. D., and Singer, L., 1972, Fertility impairment in mice on a low fluoride intake, Science 177: 893.

    Article  CAS  Google Scholar 

  • Messer, M. M., Armstrong, W. D., and Singer, L., 1973, Influence of fluoride intake on reproduction in mice, J. Nutr. 103: 1319.

    CAS  Google Scholar 

  • Mildvan, A. S., 1970, Metals in enzyme catalysis, in: The Enzymes, Vol. 2, 3rd ed. ( P. Boyer, ed.), pp. 446–536, Academic Press, New York.

    Google Scholar 

  • Miller, H. G., 1926, Potassium in animal nutrition. IV. Potassium requirements for normal growth and maintenance, J. Biol. Chem. 70: 587.

    CAS  Google Scholar 

  • Mills, C. F., Quarterman, J., Chesters, J. K., Williams, R. B., and Dalgarno, A. C., 1969, Metabolic role of zinc, Am. J. Clin. Nutr. 22: 1240.

    Google Scholar 

  • Mitchell, H. H., and Curzon, E. G., 1939, The dietary requirements of calcium and its significance, in: Actualites Scientifiques et Industrielles, pp. 36–101

    Google Scholar 

  • Herman & Co., Paris. Morris, V. C., and Levander, 0., 1970, Selenium content of foods, J. Nutr. 100: 1383.

    Google Scholar 

  • Mountain, J. T., Stockell, F. R., and Stokinger, M. E., 1956, Effect of ingested vanadium on cholesterol and phospholipid metabolism in the rabbit, Proc. Soc. Exp. Biol. Med. 92: 582.

    CAS  Google Scholar 

  • Muhler, J. C., 1970, The supply of fluorine to man. 3. Ingestion, in: Fluorides and Human Health, W.H.O. Monogr. Ser. No. 59: 32.

    Google Scholar 

  • Murthy, G. K., Rhea, U., and Peeler, J. T., 1971, Levels of antimony, cadmium, chromium, cobalt, manganese, and zinc in institutional total diets, Environ. Sci. Technol. 5: 436.

    Article  CAS  Google Scholar 

  • National Center for Health Statistics, 1966, Hypertension and hypertensive heart disease in adults, US 1960–1962, U.S. Department of Health, Education and Welfare Vital and Health Statistics Series II, No. 13.

    Google Scholar 

  • National Research Council, Division of Medical Sciences Committee on Biological Effects of Atmospheric Pollutants, 1973, Manganese, National Academy of Sciences, Washington, D.C.

    Google Scholar 

  • National Research Council, Division of Medical Sciences Committee on Biological Effects of Atmospheric Pollutants, 1974, Chromium, National Academy of Sciences, Washinton, D.C.

    Google Scholar 

  • National Research Council, Division of Medical Sciences Committee on Medical and Biologic Effects of Environmental Pollutants, 1975, Medical and Biologic Effects of Environmental Nickel, National Academy of Sciences, Washington, D.C.

    Google Scholar 

  • Nelson, A. A., Fitzhugh, O. G., and Calvery, H. O., 1943, Liver tumors following cirrhosis caused by selenium in rats, Cancer Res. 3: 230.

    CAS  Google Scholar 

  • Nielsen, F. H., 1971, Studies on the essentiality of nickel, in: Newer Trace Elements in Nutrition ( W. Mertz and W. E. Cornatzer, eds.), pp. 215–255, Marcel Dekker, New York.

    Google Scholar 

  • Nielsen, F. H., 1976, Newer trace elements and possible applications in man, in: Trace Elements in Human Health and Disease, Vol. II ( A. S. Prasad and D. Oberleas, eds.), pp. 380–387, Academic Press, New York.

    Google Scholar 

  • Nielsen, F. H., and Ollerich, D. A., 1974, Nickel: A new essential trace element, Fed. Proc. Fed. Am. Soc. Exp. Biol. 33: 1767.

    CAS  Google Scholar 

  • Nielsen, F. H., and Sauberlich, M. E., 1970, Evidence of a possible requirement for nickel in the chick, Proc. Soc. Exp. Biol. Med. 134: 845.

    CAS  Google Scholar 

  • Nielsen, F. H., O11erich, D. A., Fosmire, G. J., and Sandstead, H. H., 1974, Nickel deficiency in chicks and rats: Effects on liver morphology, function and polysomal integrity, Adv. Exp. Med. Biol. 48: 389.

    CAS  Google Scholar 

  • Nielsen, F. H., Myron, D. R., and Givand, S. H., Zimmerman, T. J., and 011erich, D. A., 1975, Nickel deficiency in rats, J. Nutr. 105: 1620.

    Google Scholar 

  • Oakes, B. W., Danks, D. M., and Campbell, P. E., 1976, Human copper deficiency: Ultrastructural studies of aorta and skin in a child with Menke’s syndrome, Exp. Mol. Pathol. 25: 82.

    Article  CAS  Google Scholar 

  • O’Dell, B. L., 1969, Effect of dietary components upon zinc availability: A review with original data, Am. J. Clin. Nutr. 22: 1315.

    Google Scholar 

  • O’Dell, B. L., 1976, Biochemistry of copper, Med. Clin. North Am. 60: 687.

    Google Scholar 

  • O’Dell, B. L., and Savage, J. E., 1960, Effect of phytic acid on zinc availability, Proc. Soc. Exp. Biol. Med. 103: 304.

    Google Scholar 

  • O’Dell, B. L., Burpo, C. E., and Savage, J. E., 1972, Evaluation of zinc availability in foodstuffs of plant and animal origin, J. Nutr. 102: 653.

    Google Scholar 

  • Ohlson, M. A., Brewer, W. D., Jackson, L., Swanson, P. P., Roberts, P. H., Mangel, M., Leverton, R. M., Chaloupka, M., Gram, M. R., Reynolds, M. S., and Lutz, R., 1952, Intakes and retentions of nitrogen, calcium and phosphorus by 136 women between 30–85 years of age, Fed. Proc. Fed. Am. Soc. Exp. Biol. 11: 775.

    CAS  Google Scholar 

  • Osis, D., Kramer, L., and Wiatrowski, E., 1972, Dietary zinc intake in man, Am. J. Clin. Nutr. 25: 582.

    CAS  Google Scholar 

  • Papavasiliou, P. S., Miller, S. T., and Cotzias, G. C., 1968, Functional interaction between biogenic amines 3’S’cAMP and manganese, Nature 220: 74.

    Article  CAS  Google Scholar 

  • Parisi, A. F., and Vallee, B. L., 1969, Zinc metalloenzymes: Characteristics and significance in biology and medicine, Am. J. Clin. Nutr. 22: 1222.

    CAS  Google Scholar 

  • Perdok, W. G., 1963, Crystallographic aspects of calcification, Arch. Oral Biol. (Suppl.) 6: 85.

    Google Scholar 

  • Perloff, D. (ed.), 1977, Symposium on hypertension, Med. Clin. North Am. 61.

    Google Scholar 

  • Peters, H. A., 1960, Chelation therapy in acute, chronic mixed porphyria in metal binding in medicine, in: Proceedings of a Symposium by Hahnemann Medical College and Hospital ( M. J. Seven, ed.), pp. 190–199, J. B. Lippincott, Philadelphia.

    Google Scholar 

  • Pidduck, H. G., Wren, P. J., and Evans, D. A. P., 1970, Hyperzincuria of diabetes mellitus and possible genetical implications of this observation, Diabetes 19: 240.

    CAS  Google Scholar 

  • Platt, R., 1942, Heredity in hypertension, Q. J. Med. 16: 111.

    Google Scholar 

  • Prasad, A. S., 1976, Deficiency of zinc in man and its toxicity, in: Trace Elements in Human Health and Disease, Vol. I ( A. S. Prasad and D. Oberleas, eds.), pp. 1–20, Academic Press, New York.

    Google Scholar 

  • Prasad, A. S., and Oberleas, D. (eds.), 1976, Trace Elements in Human Health and Disease, Vol. I, Academic Press, New York.

    Google Scholar 

  • Prasad, A. S., Halsted, J. A., and Nadimi, M., 1961, Syndrome of iron deficiency anemia, hepatosplenomegaly, hypogonadism, dwarfism, and geophagia, Am. J. Med. 31: 532.

    Article  CAS  Google Scholar 

  • Prasad, A. S., Miale, A., Fared, Z., Sandstead, H. H., and Schulert, A. R., 1963, Zinc metabolism in patients with the syndrome of iron deficiency anemia, hepatosplenomegaly, dwarfism and hypogonadism, J. Lab. Clin. Med. 61: 537.

    CAS  Google Scholar 

  • Prior, I. A. M., Evans, J. G., Harvey, H. P., Davidson, F., and Lindsey, M., 1968, Sodium intake and blood pressure in two polynesian populations, N. Engl. J. Med. 279: 515.

    Article  CAS  Google Scholar 

  • Reinhold, J. G., Nasr, K., Lahimgarzadeh, A., and Hedayati, H., 1973, Effects of purified phytate and phytate-rich bread upon metabolism of zinc, calcium, phosphorus and nitrogen, Lancet 1: 283.

    Article  CAS  Google Scholar 

  • Rickes, E. L., Brink, N. G., Koniusky, T. R., Wood, T. R., and Folkers, K., 1948, Vitamin B12, a cobalt complex, Science 108: 134.

    Article  CAS  Google Scholar 

  • Riordan, J. F., and Vallee, B. L., 1976, Structure and function of zinc metalloenzymes, in: Trace Elements in Human Health and Disease, Vol. I ( A. S. Prasad and D. Oberleas, eds.), pp. 227–256, Academic Press, New York.

    Google Scholar 

  • Roman, W., 1969, Zinc in porphyria, Am. J. Clin. Nutr. 22: 1290.

    CAS  Google Scholar 

  • Root, A. W., and Harrison, H. E., 1976, Recent advances in calcium metabolism. I. Mechanisms of calcium homeostasis, J. Pediatr. 88: 1.

    Article  CAS  Google Scholar 

  • Sandstead, H. H., 1976, Zinc, in: Nutrition Reviews’ Present Knowledge in Nutrition, pp. 290301, Nutrition Foundation, Washington, D.C.

    Google Scholar 

  • Sandstead, H. H., Prasad, A. S., Schulert, A. R., Farid, Z., Miale, A., Bassilly, S., and Darby, W. J., 1967, Human zinc deficiency, endocrine manifestations and response to treatment, Am. J. Clin. Nutr. 20: 422.

    CAS  Google Scholar 

  • Scheinberg, I. H., 1976, The effects of heredity and environment on copper metabolism, Med. Clin. North Am. 60: 705.

    CAS  Google Scholar 

  • Scheinberg, I. M., and Steinlieb, I., 1976, Copper toxicity and Wilson disease, in: Trace Elements in Human Health and Disease, Vol. I ( A. S. Prasad and D. Oberleas, eds.), pp. 415–438, Academic Press, New York.

    Google Scholar 

  • Schrauzer, G. N., 1976, Selenium and cancer: A review, Bioinorg. Chem. 5: 275.

    Article  CAS  Google Scholar 

  • Schroeder, H. A., 1966, Chromium deficiency in rats: A syndrome simulating diabetes mellitus with retarded growth, J. Nutr. 88: 439.

    CAS  Google Scholar 

  • Schroeder, H. A., 1968, The role of chromium in mammalian nutrition, Am. J. Clin. Nutr. 21:230. Schroeder, H. A., 1969, Serum cholesterol and glucose levels in rats fed refined and less refined sugars and chromium, J. Nutr. 97: 237.

    Google Scholar 

  • Schroeder, H. A., and Balassa, J. J., 1965, Influence of chromium, cadmium, and lead on rat aortic lipids and circulating cholesterol, Am. J. Physiol. 209: 433.

    CAS  Google Scholar 

  • Schroeder, H. A., Balassa, J. J., and Tipton, I. H., 1962a, Abnormal trace metals in man: Nickel, J. Chronic Dis. 15: 51.

    Article  CAS  Google Scholar 

  • Schroeder, H. A., Balassa, J. J., and Tipton, I. H., 1962b, Abnormal trace metals in man: Chromium, J. Chronic Dis. 15: 941.

    Article  CAS  Google Scholar 

  • Schroeder, H. A., Vinton, W. H., and Balassa, J. J., 1963a, Effect of chromium, cadmium, and other trace metals on the growth and survival of mice, J. Nutr. 80: 39.

    CAS  Google Scholar 

  • Schroeder, H. A., Vinton, W. H., and Balassa, J. J., 1963b, Effects of chromium, cadmium, and lead on the growth and survival of rats, J. Nutr. 80: 48.

    CAS  Google Scholar 

  • Schroeder, H. A., Balassa, J. J., and Tipton, I. H., 1963c, Abnormal trace metals in man: Vanadium, J. Chronic Dis. 16: 1047.

    Article  CAS  Google Scholar 

  • Schroeder, H. A., Balassa, J. J., and Tipton, I. H., I964a, Abnormal trace metals in man: Tin, J. Chronic Dis. 17: 483.

    Google Scholar 

  • Schroeder, H. A., Balassa, J. J., and Vinton, W. H., 19646, Chromium, lead, cadmium, nickel, and titanium in mice: Effect on mortality, tumors and tissue levels, J. Nutr. 83: 239.

    Google Scholar 

  • Schroeder, H. A., Balassa, J. J., and Vinton, W. H., 1965, Chromium, cadmium, and lead in rats: Effects on life span, tumors, and tissue levels, J. Nutr. 86: 51.

    CAS  Google Scholar 

  • Schroeder, H. A., Balassa, J. J., and Tipton, I. H., 1966a, Essential trace elements in man: Manganese, a study in homeostasis, J. Chronic Dis. 19: 545.

    Article  CAS  Google Scholar 

  • Schroeder, H. A., Nason, A. P., Tipton, I. M., and Balassa, J. J., 1966b, Essential trace metals in man: Copper, J. Chronic Dis. 19: 1007.

    Article  CAS  Google Scholar 

  • Schroeder, H. A., Nason, A. P., and Tipton, I. M., 1967, Essential metals in man: Cobalt, J. Chronic Dis. 20: 869.

    Article  CAS  Google Scholar 

  • Schroeder, H. A., Kanisaua, M., Frost, D. V., and Mitchener, M., 1968a, Germanium, tin and arsenic in rats: Effects on growth, survival, pathological lesions, and life span, J. Nutr. 96: 37.

    CAS  Google Scholar 

  • Schroeder, H. A., Mitchener, M., Balassa, J. J., Kanisaiva, M., and Nelson, A. P., 19686, Zirconium, niobium, antimony and fluorine in mice: Effect on growth, survival, and tissue levels, J. Nutr. 95: 95.

    Google Scholar 

  • Schroeder, H. A., Nason, A. P., and Tipton, I. M., 1969, Essential metals in man: Magnesium, J. Chronic Dis. 21: 815.

    Article  CAS  Google Scholar 

  • Schroeder, H. A., Frost, D. V., and Balassa, J. J., 1970, Essential trace metals in man: Selenium, J. Chronic Dis. 23: 227.

    Article  CAS  Google Scholar 

  • Schwarz, K., 1973, A bound form of silicon in GAG’s and polyuronides, Proc. Natl. Acad. Sci. U.S.A. 70: 1608.

    Article  CAS  Google Scholar 

  • Schwarz, K., 1974, Recent dietary trace element research exemplified by tin, fluorine and silicon, Fed. Proc. Fed. Am. Soc. Exp. Biol. 33: 1748.

    CAS  Google Scholar 

  • Schwarz, K., 1977, Silicon, fibre and atherosclerosis, Lancet 1: 454.

    Article  CAS  Google Scholar 

  • Schwarz, K., and Chen, S. C., 1974, A bound form of silicon as constituted of collagens, Fed. Proc. Fed. Am. Soc. Exp. Biol. 33: 704.

    Google Scholar 

  • Schwarz, K., and Foltz, C. M., 1957, Selenium as an integral part of factor 3 against dietary necrotic liver degeneration, J. Am. Chem. Soc. 79: 3292.

    Article  CAS  Google Scholar 

  • Schwarz, K., and Mertz, W., 1959, Chromium(III) and the glucose tolerance factor, Arch. Biochem. Biophys. 85: 292.

    Article  CAS  Google Scholar 

  • Schwarz, K., and Mertz, W., 1961, A physiological role of chromium (III) in glucose utilization (glucose tolerance factor), Fed. Proc. Fed. Am. Soc. Exp. Biol$120 (Suppl. 2): I l 1.

    Google Scholar 

  • Schwarz, K., and Milne, D. B., 1971, Growth effects of vanadium in the rat, Science 174: 426.

    Article  CAS  Google Scholar 

  • Schwarz, K., and Milne, D. B., 1972, Growth-promoting effects of silicon in rats, Nature 239: 333.

    Article  CAS  Google Scholar 

  • Schwarz, K., Milne, D. B., and Vinyard E., 1970, Growth effects of tin compounds in rats maintained in a trace element-controlled environment, Biochem. Biophys. Res. Commun. 40: 22.

    Article  CAS  Google Scholar 

  • Scrutton, M. C., Wu, C. W., and Goldwait, P. A., 1971, The presence and possible role of zinc in RNA polymerase obtained from Escherichia coli, Proc. Natl. Acad. Sci. U.S.A. 68: 2467.

    Article  Google Scholar 

  • Scrutton, M. C., Griminger, P., and Wallace, J. C., 1972, Pyruvate carboxylase: Bound metal content of the vertebrate liver enzyme as a function of diet, J. Biol. Chem. 247: 3305.

    CAS  Google Scholar 

  • Seelig, M. S., 1964, The requirement of magnesium by the normal adult: Summary and analysis of published data, Am. J. Clin. Nutr. 14: 342.

    Google Scholar 

  • Sherman, H. C., 1920, Phosphorus requirement of maintenance in man, J. Biol. Chem. 41: 173.

    Google Scholar 

  • Sherman, L. J., Glennon, J. A., Brech, W. J., Klomberg, G. H., and Gordon, E. S., 1968, Failure of trivalent chromium to improve hyperglycemia in diabetes mellitus, Metab. Clin. Exp. 17: 439.

    Google Scholar 

  • Shils, M. E., 1969a, Experimental human magnesium depletion, Medicine (Baltimore) 48: 61.

    Article  CAS  Google Scholar 

  • Shils, M. E., l969b, Experimental production of magnesium deficiency in man, Ann. N.Y. Acad. Sci. 162: 847.

    Google Scholar 

  • Shils, M. E., 1976a, Magnesium deficiency and calcium and PTH interrelations, in: Trace Elements in Human Health and Disease, Vol. II ( A. S. Prasad and D. Oberleas, eds.), pp. 23–46, Academic Press, New York.

    Google Scholar 

  • Shils, M. E., I976b, Magnesium, in: Nutrition Review’s Present Knowledge in Nutrition pp. 247258, Nutrition Foundation, Washington, D.C.

    Google Scholar 

  • Shou, J. C., 1975, The sodium and potassium activated enzyme system and its relationship to transport of sodium and potassium, Q. Rev. Biophys. 7: 401.

    Google Scholar 

  • Shrader, R. E., Erway, L., and Hurley, L. S., 1973, Mucopolysaccharide synthesis in the devel- o** inner ear of manganese-deficient and Pallid mutant mice, Teratology 8: 257.

    Article  CAS  Google Scholar 

  • Singer, L., and Armstrong, W. D., 1960, Regulation of human plasma fluoride concentration, J. Appl. Physiol. 15: 508.

    CAS  Google Scholar 

  • Singer, L., and Armstrong, W. D., 1962, Comparison of fluoride contents of human dental and skeletal tissues, J. Dent. Res. 41: 154.

    Article  Google Scholar 

  • Slater, J. P., Mildvan, A. S., and Loeb, L. A., 1971, Zinc in DNA polymerase, Biochem. Biophys. Res. Commun. 44: 37.

    Article  CAS  Google Scholar 

  • Snyder, F., and Cornatzer, W. F., 1958, Vanadium inhibition of phospholipid synthesis and sulfhydryl activity in rat liver, Nature 182: 462.

    Article  CAS  Google Scholar 

  • Sommer, A. L., and Lipman, C. B., 1926, Evidence on the indispensible nature of zinc and boron for higher green plants, Plant Physiol. 1: 231.

    Article  CAS  Google Scholar 

  • Soremark, R., 1967, Vanadium in some biological specimens, J. Nutr. 92: 183.

    CAS  Google Scholar 

  • Spallholz, J. E., Martin, J. L., Gerlach, M. I., and Heinzeiling, R. M., 1973a, Enhanced immunoglobin M and immunoglobin G antibody titers in mice fed selenium, Infect. Immun. 8: 841.

    CAS  Google Scholar 

  • Spallholz, J. E., Martin, J. L., Gerlach, M. L., and Heinzeiling, R. M., 1973b, Immunologic response of mice fed diets supplemented with selenite selenium, Proc. Soc. Exp. Biol. Med. 143: 685.

    CAS  Google Scholar 

  • Staub, H. W., Reussner, G., and Thiessen, R., 1969, Serum cholesterol reduction by chromium in hypercholesterolemic rats, Science 166: 746.

    Article  CAS  Google Scholar 

  • Steele, T. M., 1977, Independence of phosphate homeostasis from parathyroid function in the phosphate-depleted rat, Adv. Exp. Biol. Med. 81: 183.

    CAS  Google Scholar 

  • St. John, J. L., 1926, Growth on a synthetic ration containing small amounts of sodium, J. Biol. Chem. 77: 27.

    Google Scholar 

  • Sunderman, F. W., Nomoto, S., Morang, R., Nechay, M. W., Burke, C. N., and Nielsen, S. W., 1972a, Nickel deprivation in chicks, J. Nutr. 102: 259.

    CAS  Google Scholar 

  • Sunderman, F. W., Decsy, M. I., and McNeeley, M. D., 1972b, Nickel metabolism in health and disease, Ann. N.Y. Acad. Sci. 199: 300.

    Article  CAS  Google Scholar 

  • Swaye, P. S., Gifford, R. W., and Berre Honi, J. N., 1972, Dietary salt and essential hypertension, Am. J. Cardiol. 29: 33.

    Article  CAS  Google Scholar 

  • The Synapse 1976 (Cold Spring Harbor Symp. Quant. Biol. Vol. 50).

    Google Scholar 

  • Tappel, A. L., 1974, Selenium glutathione peroxidase and vitamin E, Am. J. Clin. Nutr. 27:960. Taves, D. R., 1970, New approach to the treatment of bone disease with fluoride, Fed. Proc. Fed. Am. Soc. Exp. Biol. 29: 1185.

    Google Scholar 

  • Thompson, W. H., and McQuarrie, I., 1933–1934, Effects of various salts on carbohydrate metabolism and blood pressure in diabetic children, Proc. Soc. Exp. Biol. Med. 31: 907.

    Google Scholar 

  • Tipton, I. H., and Cook, M. J., 1963, Trace elements in human tissue. II. Adult subjects from the U.S., Health Phys. 9: 103.

    Article  CAS  Google Scholar 

  • Tipton, I. H., Stewart, P. L., and Martin, P. G., 1966, Trace elements in diet and excreta, Health Phys. 12: 1683.

    Article  CAS  Google Scholar 

  • Todd, W. R., Elvehjem, C. A., and Hart, E. B., 1934, Zinc in the nutrition of the rat, Am. J. Physiol. 107: 146.

    CAS  Google Scholar 

  • Tucker, H. F., and Salmon, W. D., 1955, Parkeratosis or zinc deficiency in the pig, Proc. Soc. Exp. Biol. Med. 88: 613.

    CAS  Google Scholar 

  • Underwood, E. J., 1971a, Copper, in: Trace Elements in Human and Animal Nutrition, 3rd ed. ( E. J. Underwood, ed.), pp. 57–105, Academic Press, New York.

    Google Scholar 

  • Underwood, E. J., 197 lb, Zinc, in: Trace Elements in Human and Animal Nutrition 3rd ed. (E. J. Underwood, ed.), pp. 208–252, Academic Press, New York.

    Google Scholar 

  • Underwood, E. J., 1971c, Selenium, in: Trace Elements in Human and Animal Nutrition, 3rd ed. ( E. J. Underwood, ed.), pp. 323–368, Academic Press, New York.

    Google Scholar 

  • Underwood, E. J., 1971d, Fluorine, in: Trace Elements in Human and Animal Nutrition, 3rd ed., ( E. J. Underwood, ed.), pp. 369–406, Academic Press, New York.

    Google Scholar 

  • Underwood, E. J., 1975, Cobalt, Nutr. Rev. 33: 65.

    Article  CAS  Google Scholar 

  • Underwood, E. J., and Filmer, J. F., 1935, The determination of the biologically potent element (Co) in limonite, Aust. Vet. J. 11: 84.

    Article  CAS  Google Scholar 

  • Utter, M. F., 1976, The biochemistry of manganese, Med. Clin. North Am. 60: 713.

    CAS  Google Scholar 

  • Van Campen, D., and Gross, E., 1968, Influence of ascorbic acid on the absorption of copper by rats, J. Nutr. 95: 617.

    Google Scholar 

  • Wacker, W. E. C., 1976, Role of zinc in wound healing: A critical review, in: Trace Elements in Human Health and Disease, Vol. I ( A. S. Prasad and D. Oberleas, eds.), pp. 107–114, Academic Press, New York.

    Google Scholar 

  • Wacker, W. E., and Parisi, A. F., 1968a, Medical progress: Magnesium metabolism, N. Engl. J. Med. 278: 658.

    Article  CAS  Google Scholar 

  • Wacker, W. E., and Parisi, A. F., 1968b, Medical progress: Magnesium metabolism, N. Engl. J. Med. 278: 712.

    Article  CAS  Google Scholar 

  • Walker, R. M., and Linkswiler, H. M., 1972, Calcium retention in adult human male as affected by protein intake, J. Nutr. 102: 1297.

    CAS  Google Scholar 

  • Weidmann, S. M., and Weatherall, J. A., 1970, Distribution of fluorides. 3. Distribution in hard tissues, in: Fluorides and Human Health, W.H.O. Monogr. Ser. No. 59: 104.

    Google Scholar 

  • Whitehouse, M. W., Staple, E., and Kritchevsky, D., 1960, Oxidation of cholesterol by rat liver mitochondria: Effect of metal ions, Arch. Biochem. Biophys. 87: 193.

    Article  CAS  Google Scholar 

  • Widdowson, E. M., McCance, R. A., and Spray, C. M., 1951, Chemical composition of the human body, Clin. Sci. 10: 113.

    CAS  Google Scholar 

  • Wills, M. R., 1973, Intestinal absorption of calcium, Lancet 1: 820.

    Article  CAS  Google Scholar 

  • Zipkin, I., 1970, Interrelation of fluoride with other components of calcified tissue, Bibl. Nutr. Dieta 15: 62.

    CAS  Google Scholar 

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© 1980 Plenum Press, New York

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Czarnecki, S.K., Kritchevsky, D. (1980). Trace Elements. In: Alfin-Slater, R.B., Kritchevsky, D. (eds) Nutrition and the Adult. Human Nutrition, vol 3B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7216-9_8

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