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Detectors for Trace Organic Analysis by Liquid Chromatography: Principles and Applications

  • Chapter
Contemporary Topics in Analytical and Clinical Chemistry

Abstract

Although liquid column chromatography (LC) had been used as a means of chemical separation for many years prior to 1969, it was not accepted as a method useful for rapid, routine analysis, due to the relatively long times required to achieve resolution. Significant theoretical and technological advances have since been made in this field, and excellent separations can now be achieved within a few minutes using high-efficiency LC column packings. Liquid chromatography offers many advantages over gas-liquid chromatography (GLC) in that no restrictions are placed on the size, volatility, or thermal stability of the sample molecules. In addition, LC offers tremendous flexibility in the choice of mobile and stationary phases such that most sample components can be conveniently resolved using some appropriate combination of mobile and stationary phases.

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Authors and Affiliations

  1. Department of Chemistry, Purdue University, 47907, West Lafayette, Indiana, USA

    Peter T. Kissinger, Lawrence J. Felice, David J. Miner, Carl R. Preddy & Ronald E. Shoup

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  1. Peter T. Kissinger
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  2. Lawrence J. Felice
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  3. David J. Miner
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  4. Carl R. Preddy
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  5. Ronald E. Shoup
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Editors and Affiliations

  1. University of Pittsburgh, Pittsburgh, Pennsylvania, USA

    David M. Hercules

  2. Indiana University, Bloomington, Indiana, USA

    Gary M. Hieftje

  3. Technicon Instruments Corporation, Tarrytown, New York, USA

    Lloyd R. Snyder

  4. University of Wisconsin, Madison, Wisconsin, USA

    Merle A. Evenson

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Kissinger, P.T., Felice, L.J., Miner, D.J., Preddy, C.R., Shoup, R.E. (1978). Detectors for Trace Organic Analysis by Liquid Chromatography: Principles and Applications. In: Hercules, D.M., Hieftje, G.M., Snyder, L.R., Evenson, M.A. (eds) Contemporary Topics in Analytical and Clinical Chemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6731-8_3

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  • DOI: https://doi.org/10.1007/978-1-4615-6731-8_3

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