Abstract
Nutrition and toxicology are closely intertwined. Toxic substances can interfere with vital functions of the gastrointestinal tract such as digestion, absorption, excretion, and their regulatory control. From a toxicology viewpoint animals are continually challenged by compounds that are without nutritive value — material that they nevertheless ingest, inhale, or absorb. Such exposure to toxic compounds has been going on as long as life has and is not merely a consequence of the modern era of industrialization. In fact, toxin production may be considered a successful evolutionary strategy or adaptation to predators or a form of chemical warfare practiced by species as varied as insects, frogs, and plants (Rosenthal and Janzen 1979).
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McSweeney, C.S., Mackie, R.I. (1997). Gastrointestinal Detoxification and Digestive Disorders in Ruminant Animals. In: Mackie, R.I., White, B.A. (eds) Gastrointestinal Microbiology. Chapman & Hall Microbiology Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4111-0_15
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