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Biodegradable Polymers in Drug Delivery Systems

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Fundamentals and Applications of Controlled Release Drug Delivery

Part of the book series: Advances in Delivery Science and Technology ((ADST))

Abstract

This chapter is focused on the use of biodegradable polymers in long acting injectable drug delivery systems with an emphasis on marketed products. An overview is provided of how the chemical structures and physical properties of these polymers impact functionality of drug delivery systems and how to strategically select polymers for different applications. Detailed examples of biodegradable drug delivery systems are discussed with respect to routes of administration and disease states. The reader will gain information on polymer selection for different applications and on how to integrate knowledge of materials science and formulations to strategically design drug delivery systems for different pathological states.

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Author information

Authors and Affiliations

  1. Shire HGT, Cambridge, MA, 02139, USA

    Jamie Tsung

  2. Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT, USA

    Diane J. Burgess

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  1. Jamie Tsung
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  2. Diane J. Burgess
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Correspondence to Diane J. Burgess .

Editor information

Editors and Affiliations

  1. Rue Maurice Schumann 3, Phalempin, 59133, France

    Juergen Siepmann

  2. , Department of Pharmaceutics, University of Minnesota, Harvard Street SE 308, Minneapolis, 55455, Minnesota, USA

    Ronald A. Siegel

  3. , School of Pharmacy, Griffith University, Parklands Drive 1, Southport, 4215, Queensland, Australia

    Michael J. Rathbone

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Tsung, J., Burgess, D.J. (2012). Biodegradable Polymers in Drug Delivery Systems. In: Siepmann, J., Siegel, R., Rathbone, M. (eds) Fundamentals and Applications of Controlled Release Drug Delivery. Advances in Delivery Science and Technology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-0881-9_5

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