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Pregnancy, Lactation, and Breast Cancer

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Abstract

Breast cancer accounts for 20% of all cancer deaths among women in the United States. This disease is the third leading cause of cancer deaths today, affecting in their lifetime, 1 out of every 13 women. When carcinoma of the breast is diagnosed in a pregnant or lactating woman, it is particularly tragic. Breast cancer coinciding with pregnancy or lactation occurs about once in every 1000 pregnancies, and represents 1% of total breast cancers. If only women of childbearing age are considered, then the reported frequencies of coincidence range from 7 to 14% of breast cancers.

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References

  1. MacMahon, B., Cole, P., and Lin, T. M., 1970, Age at first birth and breast cancer risk, Bull. WHO 43: 209–221.

    PubMed  CAS  Google Scholar 

  2. Juret, P., Couette, J. E., Mandard, A. M., Carré, A., Delozier, T., Burne, D., and Vernhes, J. C., 1976, Age at menarche as a prognostic factor in human breast cancer, Eur. J. Cancer 12 (9): 701–704.

    PubMed  CAS  Google Scholar 

  3. Lilienfeld, A. M., Coombs, J., Bross, I. D. J., and Chamberlain, A., 1975, Marital and reproductive experience in a community-wide epidemiological study of breast cancer, Johns Hopkins Med. J. 136 (4): 157–162.

    PubMed  CAS  Google Scholar 

  4. MacMahon, B., Cole, P., and Brown, J., 1973, Etiology of human breast cancer: A review, J. Natl. Cancer Inst. 50: 21–42.

    PubMed  CAS  Google Scholar 

  5. Sherman, B. M. and Korenman, S. G., 1974, Inadequate corpus luteum function: A pathophysiological interpretation of human breast cancer epidemology, Cancer 33: 1306–1312.

    PubMed  CAS  Google Scholar 

  6. Stavraky, K. and Emmons, S. J., 1974, Breast cancer in premenopausal and postmenopausal women, J. Natl. Cancer Inst. 53 (2): 647–654.

    PubMed  CAS  Google Scholar 

  7. Leis, H. P., Jr. and Raciti, A., 1976, The search for women at high risk, in: Risk Factors in Breast Cancer ( B. A. Stoll, ed.), Heinemann Medical Books, London p. 207–225.

    Google Scholar 

  8. Thomas, D. P. and Lilfienfeld, A. M., 1976, Geographic, reproductive and sociobiological factors, in: Risk Factors in Breast Cancer ( B. A. Stoll, ed.), William Heinemann Medical Books, London p. 25–53.

    Google Scholar 

  9. Miller, A. B. and Bulbrook, R. D., 1980, The epidemiology and etiology of breast cancer, N. Engl. J. Med. 303 (2): 1246–1248.

    PubMed  CAS  Google Scholar 

  10. DeWaard, F., 1969, The epidemiology of breast cancer: Review and prospects, Int. J. Cancer 4: 577–586.

    CAS  Google Scholar 

  11. Diekamp, V., Bitran, J., and Ferguson, D. J., 1976, Breast cancer in young women, J. Reprod. Med. 17: 255–276.

    PubMed  CAS  Google Scholar 

  12. Tannenbaum, A. and Silverstone, H. 1957, Nutrition and the genesis of tumours, in: Cancer, Volume 1 ( R. W. Raven, ed.), Butterworths, London p. 306–334.

    Google Scholar 

  13. Vorherr, H. and Messer, R. H., 1978, Breast cancer: Potentially predisposing and protecting factors. Role of pregnancy, lactation and endocrine status, Am. J. Obstet. Gynecol. 130 (3): 335–358.

    PubMed  CAS  Google Scholar 

  14. Hirayama, T. and Wynder, E. L., 1962, A study of the epidemiology of cancer of the breast: The influence of hysterectomy, Cancer 15: 28–38.

    Google Scholar 

  15. Dunn, J. E., Jr., 1969, Epidemiology and possible identification of the high risk group that could develop cancer of the breast, Cancer 23: 775–780.

    PubMed  Google Scholar 

  16. Shapiro, S., Strax, P., Venet, L., and Fink, R., 1968, The search for risk factors in breast cancer, Am. J. Public Health 58: 820–835.

    CAS  Google Scholar 

  17. Cole, P., 1980, Major aspects of the epidemiology of breast cancer, Cancer (Suppl.) 46: 865–867.

    PubMed  CAS  Google Scholar 

  18. Korenman, S. G., 1980, Estrogen window hypothesis of the etiology of breast cancer, Lancet 1: 700–701.

    PubMed  CAS  Google Scholar 

  19. Lane-Claypon, J. E., 1926, A further Report on Cancer of the Breast with Special Reference to the Associated Antecedent Conditions. Ministry of Health Reports on Public Health and Medical Subjects, MO 32, His Majesty’s Stationery Office, London.

    Google Scholar 

  20. Wainwright, J. M., 1931, Comparison of conditions associated with breast cancer in Great Britain and America, Am. J. Cancer. 15: 2610.

    Google Scholar 

  21. Kamoi, M., 1960, Statistical study on relation between breast cancer and lactation period, 3. Study through relative liability, Tohoku J. Exp. Med. 72: 72–77.

    PubMed  CAS  Google Scholar 

  22. Levin, M. L., Sheeke, P. R., Graham, S., and Glidewell, O., 1964, Lactation and menstrual function as related to cancer of the breast, Am. J. Public Health. 54: 580–587.

    CAS  Google Scholar 

  23. MacMahon, B., Lin, T. M., and Lowe, C. R., 1970, Lactation and cancer of the breast. A summary of an international study, Bull WHO. 42: 185–194.

    PubMed  CAS  Google Scholar 

  24. Beatson, G. T., 1896, On the treatment of inoperable cases of carcinoma of the mamma: Suggestions for a new method of treatment with illustrative cases, Lancet 2: 104–162.

    Google Scholar 

  25. Huggins, C. and Bergenstal, D. M., 1952, Inhibition of human mammary and prostatic cancers by adrenalectomy, Cancer Res. 12: 134–141.

    PubMed  CAS  Google Scholar 

  26. McGuire, W. L., Horwitz, K. B., and De la Garza, M., 1976, A biochemical basis for selecting endocrine therapy in human breast cancer, in: Breast Cancer: Trends in Research and Treatment ( J. C. Heuson, W. H. Mattheim, and M. Rozencweig, eds.), Raven Press, New York, pp. 127–182.

    Google Scholar 

  27. Pearson, O. H. and Ray, B. S., 1960, Hypophysectomy in the treatment of metastatic mammary cancer, Am. J. Surg. 99: 544–552.

    PubMed  CAS  Google Scholar 

  28. Jensen, E. V., Smith, S., and DeSombre, E. R., 1976, Hormone dependency in breast cancer, J. Steroid Biochem. 7: 911–917.

    PubMed  CAS  Google Scholar 

  29. Minton, J. P. and Dickey, R. P., 1973, Levodopa test to predict response of carcinoma of the breast to surgical ablation of endocrine glands, Surg. Gynecol. Obstet. 136: 971–974.

    PubMed  CAS  Google Scholar 

  30. McGuire, W. L. (ed.), 1978, Hormones, Receptors and Breast Cancer, Raven Press, New York.

    Google Scholar 

  31. Santen, R. J., Worgul, T. J., Samojlik, E., Interrante, A., Boucher, N. E., White, D. S., Smart, E., Cox, C., and Wells, S. A., 1981, A randomized trial comparing surgical adrenalectomy with aminoglutethimide plus hydrocortisone in women with advanced breast cancer, N. Engl. J. Med. 305 (10): 545–551.

    PubMed  CAS  Google Scholar 

  32. Bloom, N. D., Tobin, E. H., Schreibman, B., and Degenshein, G. A., 1980, The role of progesterone receptors in the management of advanced breast cancer, Cancer 45 (12): 2992–2997.

    PubMed  CAS  Google Scholar 

  33. McGuire, W. L., 1978, Hormone receptors: Their role in predicting prognosis and response to endocrine therapy, Semin. Oncol. 5 (4): 428–433.

    PubMed  CAS  Google Scholar 

  34. Brooks, S. C., Saunders, D. E., Singhakowinta, A., and Vaitkevicius, V. K., 1980, Relation of tumor content of estrogen and progesterone receptors with response of patient to endocrine therapy, Cancer 46: 2775–2778.

    PubMed  CAS  Google Scholar 

  35. Dao, T. L. and Nemoto, T., 1980, Steroid receptors and response to endocrine ablations in women with metastatic cancer of the breast, Cancer 46: 2779–2782.

    PubMed  CAS  Google Scholar 

  36. Degenshein, G. A., Bloom, N., and Tobin, E., 1980, The value of progesterone receptor assays in the management of advanced breast cancer, Cancer 46: 2789–2793.

    PubMed  CAS  Google Scholar 

  37. Manni, A., Arafah, B. V., and Pearson, O., 1980, Estrogen and progesterone receptors in the prediction of response of breast cancer to endocrine therapy, Cancer 46: 2838–2841.

    PubMed  CAS  Google Scholar 

  38. Pertschuk, L. P., Tobin, E. H., Gaetjens, E., Carter, A. C., Degenshein, G. A., Bloom, N. D., and Brigati, D. J., 1980, Histochemical assay of estrogen and progesterone receptors in breast cancer: Correlation with biochemical assays and patients response to endocrine therapies, Cancer 46: 2896–2901.

    PubMed  CAS  Google Scholar 

  39. Skinner, L. G., Barnes, D. M., and Ribeiro, G. G., 1980, The clinical value of multiple steroid receptor assays in breast cancer management, Cancer 46: 2939–2945.

    PubMed  CAS  Google Scholar 

  40. Young, P. C. M., Ehrlich, C. E., and Einhorn, L. H., 1980, Relationship between steroid receptors and response to endocrine therapy and cytotoxic chemotherapy in metastatic breast cancer, Cancer 46: 2961–2963.

    PubMed  CAS  Google Scholar 

  41. DeSombre, E. R., Kledzik, G., Marshall, S., and Meites, J., 1976, Estrogen and prolactin receptor concentration in rat mammary tumors and response to endocrine ablation, Cancer Res. 36: 354–358.

    PubMed  CAS  Google Scholar 

  42. Allegra, J. C., Lippman, M. E., Thompson, E. B., Simon, R., Barlock, A., Green, L., Huff, K., Hoan My T. Do, and Aitken, S. C., 1979, Distribution, frequency and quantitative analyses of estrogen, progesterone, androgen and glucocorticoid receptors in human breast cancer, Cancer Res. 39: 1447–1454.

    PubMed  CAS  Google Scholar 

  43. Horwitz, K. B., McGuire, W. L., Pearson, O. H., and Segaloff, A., 1975, Predicting response to endocrine therapy in human breast cancer: A hypothesis, Science 189: 726–727.

    PubMed  CAS  Google Scholar 

  44. Freifeld, M. L., Feil, P. D., and Bardin, C. W., 1974, The in vivo regulation of the progesterone receptor in guinea pig uterus: Dependence on estrogen and progesterone, Steroids 23: 93–103.

    PubMed  CAS  Google Scholar 

  45. Horwitz, K. B. and McGuire, W. L., 1975, Specific progesterone receptors in human breast cancer, Steroids 25: 497–505.

    PubMed  CAS  Google Scholar 

  46. McGuire, W. L., 1980, An update on estrogen and progesterone receptors in prognosis for primary and advanced breast cancer, in: Hormones and Cancer ( S. Iacobelli, ed.), Raven Press, New York.

    Google Scholar 

  47. McCormick, G. M. and Moon, R. C., 1965, Effect of pregnancy and lactation on growth of mammary tumors induced by 7,12-Dimethylbenz (A) anthracene (DMBA), Br. J. Cancer 19: 160–166.

    PubMed  CAS  Google Scholar 

  48. Huggins, C. and Yang, N. C., 1962, Induction and extinction of mammary cancer. A striking effect of hydrocarbons permits analysis of mechanisms of causes and cures of breast cancer, Science 137: 257–262.

    PubMed  CAS  Google Scholar 

  49. Huggins, C., 1965, Two principles in endocrine therapy of cancers: Hormone deprival and hormone interference, Cancer Res. 25: 1163–1175.

    PubMed  CAS  Google Scholar 

  50. McCormick, G. M. and Moon, R. C., 1973, Effect of increasing doses of estrogen and progesterone on mammary carcinogenesis in the rat, Eur. J. Cancer. 9: 483–486.

    PubMed  CAS  Google Scholar 

  51. Witliff, J. L., Gardner, D. G., Battema, W. L., and Gilbert, P. J., 1972, Specific estrogen receptors in the neoplastic and lactating mammary gland of the rat, Biochem. Biophys. Res. Commun. 48: 119–125.

    Google Scholar 

  52. Speroff, L., 1981, The ovary, in: Endocrinology and Metabolism ( P. Felig, J. D. Baxter, A. E. Broaders, and L. A. Frohman, eds.), Mcgraw-Hill Book Co., New York, p. 688.

    Google Scholar 

  53. Meites, J., Cassell, E. E., and Clark, J. H., 1971, Estrogen inhibition of mammary tumor growth in rats: counteraction by prolactin, Proc. Soc. Exp. Biol. Med. 137: 1225–1227.

    PubMed  CAS  Google Scholar 

  54. Shiu, R. P. C., 1979, Prolactin receptors in human breast cancer cells in long-term tissue culture, Cancer Res. 39: 4381–4386.

    PubMed  CAS  Google Scholar 

  55. Wilson, R. G., Forrest, A. P. M., Boyns, A. R., and Griffiths, K., 1973, Studies on human prolactin, in: Human Prolactin, Proceedings of the International Symposium on Human Prolactin (J. L. Pastells, C.Robyn, and F.J. G. Ebling, eds. ), Brussels, pp. 11–23.

    Google Scholar 

  56. Boyns, A. R., Cole, E. N., Griffiths, K., Roberts, M. M., Buchan, R., Wilson, R. G., and Forrest, A. P. M., 1973, Plasma prolactin in breast cancer, Eur. J. Cancer 9: 99–102.

    PubMed  CAS  Google Scholar 

  57. Dickey, R. P. and Minton, J. P., 1972, L-Dopa effect on prolactin, F.S.H. and L.H. in women with advanced breast cancer: A preliminary report, Am. J. Obstet. Gynecol. 114: 267–269.

    PubMed  CAS  Google Scholar 

  58. Franks, S., Ralphs, D. N. L., Seagroatti, V., and Jacobs, H. S., 1974, Prolactin concentrations in patients with breast cancer, Br. Med. J. 4: 320–321.

    PubMed  CAS  Google Scholar 

  59. Boston Collaborative Drug Surveillance Program, 1974, Reserpine and breast cancer, Lancet 2: 669–671.

    Google Scholar 

  60. Armstrong, B., Stevens, N., and Doll, R., 1974, Retrospective study of the association between use of ranwolfia derivatives and breast cancer in English women, Lancet 2: 672–675.

    PubMed  CAS  Google Scholar 

  61. Heinomen, O. P., Shapiro, S., Tuominen, L., and Turunen, M. I., 1974, Reserpine use in relation to breast cancer, Lancet 2: 675–677.

    Google Scholar 

  62. Minton, J. P. and Dickey, R. P., 1972, Prolactin, FSH and LH in breast cancer: Effect of levodopa and oophorectomy, Lancet 1: 1069–1070.

    PubMed  CAS  Google Scholar 

  63. L’Hermite, M., Robyn, C., Heuson, J. C., and Rozencweig, M., 1974, Letter: Breast cancer regression under estrogen therapy, Br. Med. J. 1: 390.

    PubMed  Google Scholar 

  64. Wilson, R. G., Buchan, R., Roberts, M. M., Forrest, A. P. M., Boyns, A. R., Cole, E. N., and Griffith, K., 1974, Plasma prolactin and breast cancer, Cancer 33: 1325–1327.

    PubMed  CAS  Google Scholar 

  65. Moore, D. H., Long, C. A., Vaidya, A. B., Sheffield, J. B., Dion, A. S., and Lasfargucs, E. Y., 1979, Mammary tumors viruses, Adv. Cancer Res. 29: 347–417.

    PubMed  CAS  Google Scholar 

  66. Dalton, A. J., Heine, V. J., and Melnick, J. L., 1975, Symposium: Characterization of oncornaviruses and related viruses—A report, J. Natl. Cancer Inst. 55: 941–942.

    PubMed  CAS  Google Scholar 

  67. Moore, D. H., Charney, J., Kramarsky, B., Lasfargues, E. Y., Sarkar, N. H., Brennan, M. J., Burrows, J. H., Sirsat, S. M., Paymaster, J. C., and Vaidya, A. B., 1971, Search for a human breast cancer virus, Nature (London) 229: 611–614.

    CAS  Google Scholar 

  68. Gerard, G. F., Loewenstein, P. M., Green, M., and Rottman, F., 1975, Detection of reverse transcriptase in human breast tumours with poly(Cm)-oligo (dG), Nature 256: 140–143.

    PubMed  CAS  Google Scholar 

  69. Axel, R., Gulati, S. C., and Spiegelman, S., 1972, Particles containing RNA-instructed DNA polynurase and virus-related RNA in human breast cancers, Proc. Nat. Acad. Sci. USA 69: 3133–3137.

    PubMed  CAS  Google Scholar 

  70. Axel, R., Schlom, J., and Spiegelman, S., 1972, Presence in human breast cancer of RNA humologous to mouse mammary tumor virus RNA, Nature (London) 235: 32–36.

    CAS  Google Scholar 

  71. Spiegelman, S., Axel, R., and Schlom, J., 1972, Virus related RNA in human and mouse mammary tumors, J. Natl. Cancer Inst. 48: 1205–1211.

    PubMed  CAS  Google Scholar 

  72. Mesa-Tejada, R., Keydar, I., Ramanrayanan, M., Ohno, T., Fenoglio, C., and Spiegelman, S., 1978, Detection in human breast carcinomas of an antigen immunologically related to a group specific antigen of mouse mammary tumor virus, Proc. Nat. Acad. Sci. USA 75: 1529–1533.

    PubMed  CAS  Google Scholar 

  73. Vaidya, A. B., Black, M. M., Dion, A. S., and Moore, D. H., 1974, Homology between human breast tumor RNA and mouse mammary tumor virus genome, Nature (London) 249: 565–567.

    CAS  Google Scholar 

  74. Keydar, I., Mesa-Tejada, R., Ramanarayanan, M., Ohno, T., Fenoglio, C., and Spiegelman, S., 1978, Detection of viral proteins in mouse mammary tumors by immunoperoxidase staining of paraffin sections, Proc. Nat. Acad. Sci. USA 75: 1524–1528.

    PubMed  CAS  Google Scholar 

  75. Bowen, J. M., Dmochowski, L., Miller, M. F., Priori, E. S., Seman, G., Dodson, M. L., and Maruyama, K., 1976, Implications of humoral antibody in mice and humans to breast tumor and mouse mammary tumor virus-associated antigens, Cancer Res. 36: 759–764.

    PubMed  CAS  Google Scholar 

  76. Hoshino, M. and Dmochowski, L., 1973, Electron microscope study of antigens in cells of mouse mammary tumor cell lines by peroxidase-labeled antibodies in sera of mammary tumor bearing mice and of patients with breast cancer, Cancer Res. 33: 2551–2561.

    PubMed  CAS  Google Scholar 

  77. Miller, M. F., Dmochowski, L., and Bowen, J. M., 1977, Immunoelectron microscope studies of antibodies in mouse sera directed against mouse mammary tumor virus, Cancer Res. 37: 2086–2091.

    PubMed  CAS  Google Scholar 

  78. Priori, E. S., Anderson, D. E., Williams, W. C., and Dmochowski; L., 1972, Immunological studies on human breast carcinoma and mouse mammary tumors, J. Natl. Cancer Inst. 48: 1131–1135.

    PubMed  CAS  Google Scholar 

  79. Black, M. M., 1977, Immunogenicity and MµMTV-like antigenicity of human breast cancer tissues, in: Contemporary topics in immunology, ( M. G. Hanna Jr. and F. Rapp, eds.) Plenum Press, New York, p. 239–262.

    Google Scholar 

  80. Black, M. M., Moore, D. H., Shore, B., Zachrau, R. E., and Leis, H. P., Jr., 1974, Effect of murine milk samples and human breast tissues on human leukocyte migration indices, Cancer Res. 34: 1054–1060.

    PubMed  CAS  Google Scholar 

  81. Black, M. M., Zachrau, R. E., Shore, B., Moore, D. H., and Leis, H. P., Jr., 1975, Prognostically favorable immunogens of human breast cancer tissue: Antigenic similarity to murine mammary tumor virus, Cancer 35: 121–128.

    PubMed  CAS  Google Scholar 

  82. Black, M. M., Zachrau, R. E., Dion, A. S., Shore, B., Fine, D. L., Leis, H. P., Jr., and Williams, C. J., 1976, Biological considerations of tumor-specific and virus-associated antigens of human breast cancers, Cancer Res. 36: 4137–4142.

    PubMed  CAS  Google Scholar 

  83. Black, M. M., Zachrau, R. E., and Shore, B., 1981, MµMTV-like characteristics of human breast carcinoma immunogens, in: Bibliothica Haematologia Vol. 43, ( J. Clemmenson and D. S. Yohn, eds.), 559–564, Karger Co., New York.

    Google Scholar 

  84. Black, M. M., Zachrau, R. E., Shore, B., 1976, Biological considerations of tumor-specific and virus associated antigens of human breast cancers, Cancer Res. 36 (2 pt 2): 769–774.

    PubMed  CAS  Google Scholar 

  85. Zachrau, R. E., Black, M. M., Dion, A. S., Shore, B., Isac, M., Andrade, A. M., and Williams, C. J., 1976, Prognostically significant protein components of human breast cancer tissues, Cancer Res. 36: 3143–3146.

    PubMed  CAS  Google Scholar 

  86. Sarkar, N. H. and Moore, D. H., 1972, Electron microscopy in mammary cancer research, J. Natl. Cancer Inst. 48: 1051–1058.

    PubMed  CAS  Google Scholar 

  87. Sarkar, N. H. and Moore, D. H., 1972, On the possibility of a human breast cancer virus, Nature (London) 236: 103–106.

    CAS  Google Scholar 

  88. Schlom, J. and Spiegelman, S., 1971, Simultaneous detection of reverse transcriptase and high molecular weight RNA unique to oncogenic RNA virsus, Science 174: 840–843.

    PubMed  CAS  Google Scholar 

  89. Dion, A. S., Vaidya, A. B., and Fout, G. S., 1974, Isolation and characterization of RNA-directed DNA polymerase from a B-type RNA tumor virus, J. Virol. 14: 40–46.

    PubMed  CAS  Google Scholar 

  90. Schlom, J., Colcher, D., Spiegelman, S., Gillespie, S., and Gillespie, D., 1973, Quantitation of RNA tumor viruses and viruslike particles in human milk by hybridization to polyadenylic acid sequences, Science 179: 696–698.

    PubMed  CAS  Google Scholar 

  91. Axel, R., Schlom, J., and Spiegelman, S., 1972, Evidence for translation of viral-specific RNA in cells of a mouse mammary carcinoma, PNAS (USA) 69: 535–538.

    CAS  Google Scholar 

  92. Fraumeni, J. F., Jr., and Miller, R. W., 1971, Breast cancer from breast-feeding, Lancet 2: 1196–1197.

    PubMed  Google Scholar 

  93. Tokuhata, G. K., 1969, Morbidity and mortality among offspring of breast cancer mothers, Am. J. Epidemiol. 89: 139–153.

    PubMed  CAS  Google Scholar 

  94. Anderson, D. E., 1975, Genetics and breast cancer, in: Early Breast Cancer: Detection and Treatment ( H. S. Gallager, ed.), John Wiley, New York, p. 41–49.

    Google Scholar 

  95. Juret, P., 1981, Reproductive factors and the natural history of breast cancers. Reviews on endocrine-related cancer, Cancer 9: 29–35.

    Google Scholar 

  96. Dole, R., Muir, C., and Waterhouse, J. (eds.), 1970, International Union Against Cancer (UICC), Cancer Incidence in Five Continents, Volume 2, Springer-Verlag, Berlin.

    Google Scholar 

  97. Mausner, J. S., Shimkin, M. B., Moss, N. H., and Rosemond, G. P., 1969, Cancer of the breast in Philadelphia hospitals, 1951–1964, Cancer 231: 260–274.

    Google Scholar 

  98. Applewhite, R. R., Smith, L. R., and DiVincenti, F., 1973, Carcinoma of the breast associated with pregnancy and lactation, Am. Surg. 39: 101–104.

    PubMed  CAS  Google Scholar 

  99. Treves, N., and Holleb, A. I., 1958, A report of 549 cases of breast cancer in women 35 years of age or younger, Surg. Gynecol. Obstet. 107: 271–283.

    PubMed  CAS  Google Scholar 

  100. Horsley, J. S., III, Alrich, E. M., and Wright, C. B., 1969, Carcinoma of the breast in women 35 years of age or younger, Annals Surg. 169: 839–843.

    Google Scholar 

  101. Cancer Statistics: 25 year cancer survey, 1975, American Cancer Society Professional Education Publication, Ca—A Cancer Journal for Clinicians 25:2.

    Google Scholar 

  102. Rosemond, G. P., and Mayer, W. P., 1971, Pregnancy and breast cancer, in: Breast Cancer—Early and Late, (M. D. Anderson Hospital) Year Book Medical, Chicago, pp. 227–235.

    Google Scholar 

  103. Rosemond, G. P., 1964, Management of patients with carcinoma of the breast in pregnancy, Ann. N.Y. Acad. Sci. 114: 851–856.

    Google Scholar 

  104. Peters, M. V., 1968, The effect of pregnancy in breast cancer, in: Prognostic Factors in Breast Cancer ( A. P. M. Forrest and P. B. Kunkler, eds.), Williams and Wilkins Co., Baltimore, p. 65–80.

    Google Scholar 

  105. White, T. T. and White, W. C., 1956, Breast cancer and pregnancy: report of 39 cases followed five years, Ann. Surg. 144: 389–391.

    Google Scholar 

  106. Byrd, B. F., Jr., Bayer, D. S., Robertson, J. C., and Stephenson, S. E., Jr., 1962, Treatment of breast tumors associated with pregnancy and lactation, Ann. Surg. 155: 940–947.

    PubMed  Google Scholar 

  107. Donegan, W. L., 1977, Breast cancer and pregnancy, Obstet. Gynecol. 50 (2): 244–252.

    PubMed  CAS  Google Scholar 

  108. Goldsmith, H. S., 1974, Milk-rejection sign of breast cancer, Am. J. Surg. 127: 280–281.

    PubMed  CAS  Google Scholar 

  109. Cheek, J. H., 1953, Survey of current opinions concerning carcinoma of the breast occuring during pregnancy, Arch. Surg. 66: 664–668.

    CAS  Google Scholar 

  110. Costarides, J. and Theofanides, C., 1963, Carcinoma of the breast during pregnancy or lactation, J. Int. Coll. Surg. 40: 146–151.

    PubMed  CAS  Google Scholar 

  111. Haagensen, C. D., 1967, Cancer of the breast in pregnancy and during lactation, Am. J. Obstet. Gynecol. 98: 141–149.

    PubMed  CAS  Google Scholar 

  112. Rissanen, P. M., 1968, Carcinoma of the breast during pregnancy and lactation, Br. J. Cancer. 22: 663–668.

    PubMed  CAS  Google Scholar 

  113. Helman, P. and Bennett, M. B., 1963, Breast cancer and pregnancy, S. Afr. Med. J. 37: 1236–1239.

    Google Scholar 

  114. Erwald, R., 1967, Mammary carcinoma and pregnancy, Acta Obstet. Gynecol. Scand. 46: 316–326.

    PubMed  CAS  Google Scholar 

  115. Potter, J. F. and Schoeneman, M., 1970, Metastases of maternal cancer to the placenta and fetus, Cancer 25: 380–388.

    PubMed  CAS  Google Scholar 

  116. Cheek, J. H., 1973, Cancer of the breast in pregnancy and lactation, Am. J. Surg. 126: 729–731.

    PubMed  CAS  Google Scholar 

  117. Peete, C. H., Jr., Shimkin, M. B., and Moss, N. H., 1969, Cancer of the breast in pregnancy, N. Carolina Med. J. 27: 514–520.

    Google Scholar 

  118. Earley, T. K., Gallagher, J. Q., and Chapman, K. E., 1969, Carcinoma of the breast in women under thirty years of age, Am. J. Surg. 118: 832–834.

    PubMed  CAS  Google Scholar 

  119. Haagensen, C. D., 1971, Diseases of the breast, W. B. Saunders Co., Philadelphia, p. 662.

    Google Scholar 

  120. Holleb, A. I. and Farrow, J. H., 1962, The regulation of carcinoma of the breast and pregnancy in 283 patients, Surg. Gynecol. Obstet. 115: 65–71.

    PubMed  CAS  Google Scholar 

  121. Rosemond, G. P., 1963, Carcinoma of the breast during pregnancy, Clin. Obstet. Gynecol. 6: 994–1001.

    Google Scholar 

  122. Bunker, M. L. and Peters, M. V., 1963, Breast cancer associated with pregnancy or lactation, Am. J. Obstet. Gynecol. 85: 312–319.

    PubMed  CAS  Google Scholar 

  123. Devitt, J. E., Beattie, W. G., and Stoddart, T. G., 1964, Carcinoma of the breast and pregnancy, Can. J. Surg. 7: 124–128.

    PubMed  CAS  Google Scholar 

  124. Matsumoto, K. Ochi, H., Momura, Y. Takatani, O., Izuo, M., Okamoto, R., and Sugano, H., 1978, Progesterone and estrogene receptors in Japanese breast cancer, in: Hormones, Receptors and Breast Cancer ( W. L. McGuire, ed.), Raven Press, New York, pp. 43–58.

    Google Scholar 

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Authors and Affiliations

  1. Departments of Medicine and Biochemistry, Biophysics, and Genetics, University of Colorado Health Sciences Center, Denver, Colorado, 80262, USA

    Mary B. Mockus & Kathryn B. Horwitz

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  1. Mary B. Mockus
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  2. Kathryn B. Horwitz
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Editors and Affiliations

  1. Department of Physiology, University of Colorado School of Medicine, 80262, Denver, Colorado, USA

    Margaret C. Neville Ph.D.

  2. Department of Pediatrics, University of Colorado School of Medicine, 80262, Denver, Colorado, USA

    Marianne R. Neifert M.D.

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© 1983 Plenum Press, New York

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Mockus, M.B., Horwitz, K.B. (1983). Pregnancy, Lactation, and Breast Cancer. In: Neville, M.C., Neifert, M.R. (eds) Lactation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3688-4_15

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  • DOI: https://doi.org/10.1007/978-1-4613-3688-4_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-3690-7

  • Online ISBN: 978-1-4613-3688-4

  • eBook Packages: Springer Book Archive

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