Renal Transplantation in Systemic Inherited and Metabolic Disease

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Therapy of Renal Diseases and Related Disorders
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Abstract

The ever-growing success of renal transplantation in the treatment of end-stage renal disease has encouraged nephrologists and transplant surgeons to broaden its application. Previously reserved for the young, healthy individual with chronic glomerulonephritis, renal transplantation is now available to less than ideal patients, high-risk patients, and those suffering from systemic disorders. In some clinical situations such as enzyme deficiency disorders, renal transplantation may offer an advantage over dialysis in that the transplanted organ may act as a source for a deficient cell product as well as a kidney. Experience has demonstrated that transplantation can be successfully accomplished in a variety of common and uncommon renal diseases. Thus patients with many causes of renal failure have benefitted from this form of therapy. In turn, the community of practicing and investigative nephrologists has gained considerable insight into the nature of these several renal diseases.

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Lederer, E.D., Suki, W.N. (1991). Renal Transplantation in Systemic Inherited and Metabolic Disease. In: Suki, W.N., Massry, S.G. (eds) Therapy of Renal Diseases and Related Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0689-4_59

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