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Mode of Action of Antifungals of Use in Immunocompromised Patients. Focus on Candida Glabrata and Histoplasma Capsulatum

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Mycoses in AIDS Patients

Abstract

During recent years considerable advances have been made in the identification of potential targets for antifungal agents. The most important antifungals for use in immunocompromised patients interfere with targets in the plasma membrane (polyenes), nucleus (5-fluorocytosine) or smooth endoplasmic reticulum (allylamines, morpholines, azole derivatives).

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Authors and Affiliations

  1. Janssen Research Foundation, B2340, Beerse, Belgium

    Hugo Vanden Bossche, Patrick Marichal, Jos Gorrens, Danny Bellens, Marie-Claire Coene, Wim Lauwers, Ludo Le Jeune, Henri Moereels & Paul A. J. Janssen

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  1. Hugo Vanden Bossche
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  2. Patrick Marichal
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  3. Jos Gorrens
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  4. Danny Bellens
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  5. Marie-Claire Coene
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  6. Wim Lauwers
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  7. Ludo Le Jeune
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  8. Henri Moereels
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  9. Paul A. J. Janssen
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Editors and Affiliations

  1. Janssen Research Foundation, Beerse, Belgium

    Hugo Vanden Bossche , Geert Cauwenbergh  & Jan Van Cutsem ,  & 

  2. Central Public Health Laboratory, London, UK

    Donald W. R. Mackenzie

  3. Institut Pasteur, Paris, France

    Edouard Drouhet  & Bertrand Dupont  & 

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© 1990 Plenum Press, New York

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Vanden Bossche, H. et al. (1990). Mode of Action of Antifungals of Use in Immunocompromised Patients. Focus on Candida Glabrata and Histoplasma Capsulatum . In: Bossche, H.V., Mackenzie, D.W.R., Cauwenbergh, G., Van Cutsem, J., Drouhet, E., Dupont, B. (eds) Mycoses in AIDS Patients. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0655-9_22

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  • DOI: https://doi.org/10.1007/978-1-4613-0655-9_22

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