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Class IIa Bacteriocins: Current Knowledge and Perspectives

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Prokaryotic Antimicrobial Peptides

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Abstract

Lactic acid bacteria (LAB) are known to produce antibacterial peptides and small proteins called bacteriocins, which enable them to compete against other bacteria in the environment. Bacteriocins fall structurally and chemically into three different classes, I, II, and III. Bacteriocins are ribosomally synthesized peptides with antagonism against closely related bacteria. This late observation has evolved because bacteriocins active against Gram-negative bacteria have recently been reported. Members of class IIa bacteriocins, referred to as pediocin-like bacteriocins, are among the most studied bacteriocins. This chapter is aimed at providing an updated review on the biology of class IIa bacteriocins.

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Acknowledgments

The authors would like to thank Prof. Dzung Diep, Dr. Bruce Seal, Prof. Mike Chikindas, and Dr. Sutyak Noll for critical reading of the manuscript and stimulating discussions. YB was recipient of PhD scholarship awarded by la Région des Pays de la Loire http://www.paysdelaloire.fr/

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  1. Department of Research into Sanitary Risks and Biotechnology of Reproduction, UPSP 5301 DGER, Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering (ONIRIS), La Chantrerie Cedex 03, BP 40706, 44307, Nantes, France

    Djamel Drider

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  1. Yanath Belguesmia
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  2. Karim Naghmouchi
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  3. Nour-Eddine Chihib
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  4. Djamel Drider
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Correspondence to Djamel Drider .

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  1. Nantes-Atlantic Natl. College of Vet. Me, Food Sci. & Eng., ONIRIS, Nantes, France

    Djamel Drider

  2. Dépt. Régulations, Développement et, Diversité Moléculaire, Muséum National d'Histoire Naturelle, rue Cuvier 57, Paris, 75005, France

    Sylvie Rebuffat

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Belguesmia, Y., Naghmouchi, K., Chihib, NE., Drider, D. (2011). Class IIa Bacteriocins: Current Knowledge and Perspectives. In: Drider, D., Rebuffat, S. (eds) Prokaryotic Antimicrobial Peptides. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7692-5_10

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