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The Digital World of Cytogenetic and Cytogenomic Web Resources

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Cancer Cytogenetics and Cytogenomics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2825))

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Abstract

The dynamic growth of technological capabilities at the cellular and molecular level has led to a rapid increase in the amount of data on the genes and genomes of organisms. In order to store, access, compare, validate, classify, and understand the massive data generated by different researchers, and to promote effective communication among research communities, various genome and cytogenetic online databases have been established. These data platforms/resources are essential not only for computational analyses and theoretical syntheses but also for hel** researchers select future research topics and prioritize molecular targets. Furthermore, they are valuable for identifying shared recurrent genomic patterns related to human diseases and for avoiding unnecessary duplications among different researchers. The website interface, menu, graphics, animations, text layout, and data from databases are displayed by a front end on the screen of a monitor or smartphone. A database front-end refers to the user interface or application that enables accessing tabular, structured, or raw data stored in the database. The Internet makes it possible to reach a greater number of users around the world and gives them quick access to information stored in databases. The number of ways of presenting this data by front-ends increases as well. This requires unifying the ways of operating and presenting information by front-ends and ensuring contextual switching between front-ends of different databases. This chapter aims to present selected cytogenetic and cytogenomic Internet resources in terms of obtaining the needed information and to indicate how to increase the efficiency of access to stored information. Through a brief introduction of these databases and by providing examples of their usage in cytogenetic analyses, we aim to bridge the gap between cytogenetics and molecular genomics by encouraging their utilization.

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Authors and Affiliations

  1. Institute of Biological Sciences, Department of Biotechnology, Laboratory of Bioinformatics and Control of Bioprocesses, University of Zielona Góra, Zielona Góra, Poland

    Andrzej Kasperski

  2. Center for Molecular Medicine and Genetics, and Department of Pathology, Wayne State University School of Medicine, Detroit, MI, USA

    Henry H. Heng

Authors
  1. Andrzej Kasperski
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  2. Henry H. Heng
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Correspondence to Andrzej Kasperski .

Editor information

Editors and Affiliations

  1. Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, TX, USA

    **g Christine Ye

  2. Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA

    Henry H. Heng

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Kasperski, A., Heng, H.H. (2024). The Digital World of Cytogenetic and Cytogenomic Web Resources. In: Ye, J.C., Heng, H.H. (eds) Cancer Cytogenetics and Cytogenomics. Methods in Molecular Biology, vol 2825. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3946-7_21

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  • DOI: https://doi.org/10.1007/978-1-0716-3946-7_21

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3945-0

  • Online ISBN: 978-1-0716-3946-7

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