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Recent Advancements in Radiopharmaceuticals for Infection Imaging

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Intracellular Pathogens

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2813))

Abstract

COVID-19 pandemic has heightened the interest toward diagnosis and treatment of infectious diseases. Nuclear medicine, with its powerful scintigraphic, single photon emission computer tomography (SPECT), and positron emission tomography (PET) imaging modalities, has always played an important role in diagnosis of infections and distinguishing them from the sterile inflammation. In addition to the clinically available radiopharmaceuticals, there has been a decades-long effort to develop more specific imaging agents with some examples being radiolabeled antibiotics and antimicrobial peptides for bacterial imaging, radiolabeled antifungals for fungal infections imaging, radiolabeled pathogen-specific antibodies, and molecular engineered constructs. In this chapter, we discuss some examples of the work published in the last decade on develo** nuclear imaging agents for bacterial, fungal, and viral infections to generate more interest among nuclear medicine community toward conducting clinical trials of these novel probes, as well as toward develo** novel radiotracers for imaging infections.

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Authors and Affiliations

  1. College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada

    Ekaterina Dadachova

  2. Universidade Tecnológica Federal do Paraná, Dois Vizinhos, Brazil

    Drauzio E. N. Rangel

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  1. Ekaterina Dadachova
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  2. Drauzio E. N. Rangel
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Correspondence to Ekaterina Dadachova .

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Editors and Affiliations

  1. Vaccine and Infectious Disease Organization, University of Saskatchewan, Saskatoon, SK, Canada

    Aneesh Thakur

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Dadachova, E., Rangel, D.E.N. (2024). Recent Advancements in Radiopharmaceuticals for Infection Imaging. In: Thakur, A. (eds) Intracellular Pathogens. Methods in Molecular Biology, vol 2813. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3890-3_14

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  • DOI: https://doi.org/10.1007/978-1-0716-3890-3_14

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3889-7

  • Online ISBN: 978-1-0716-3890-3

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