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Nanofabrication of Catechin-Loaded Alginate, Pectin, and Chitosan Polymeric Nanoparticles

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Abstract

Drug delivery with appropriate dosage and interval at the target site by nanofabrication is the choice of research at present time. Use of polymers, viz., alginate, pectin, and chitosan, has been accepted by the European Pharmacopoeia as a newer process for structured drug delivery systems. Catechins, a predominant form of flavanols found naturally, have drawn particular consideration due to their relatively high antioxidant capacity in biological systems. The application of catechin is restricted because of its unstable nature in solution with reduced bioavailability in the body. Designing and nanofabrication not only decrease the repeated administration due to its sustained release properties to prevail over noncompliance but also facilitate the increase of the therapeutic value by reducing toxicity and escalating the bioavailability, stability, and target ability to the specific cell or organ. In this chapter, we have described nanofabrication of catechin-loaded alginate, pectin, and chitosan polymeric nanoparticles as a potent method to protect controlled release and to increase the action of bioactive compounds at the target cell or organ.

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Authors and Affiliations

  1. Division of Medicine, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar, Uttarpradesh, India

    Deba Brata Mondal, Jithin Mullakkalparambil Velayudhan, Aishwarya Lekshman, Ravi Shankar Kumar Mandal & Raguvaran Raja

  2. Division of Surgery, ICAR-Indian Veterinary Research Institute [Deemed University], Izatnagar, Uttarpradesh, India

    Naveen Kumar

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  1. Deba Brata Mondal
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  2. Jithin Mullakkalparambil Velayudhan
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  3. Aishwarya Lekshman
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  5. Raguvaran Raja
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  6. Naveen Kumar
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Editors and Affiliations

  1. ICAR-Indian Veterinary Research Institute, Izatnagar, India

    Naveen Kumar

  2. Sardar Vallabhbhai Patel University of Agriculture and Technology, Meerut, India

    Vineet Kumar

  3. ICAR-Indian Veterinary Research Institute, Izatnagar, India

    Sameer Shrivastava

  4. Acharya Narendra Dev University of Agriculture and Technology, Ayodhya, India

    Anil Kumar Gangwar

  5. Indian Veterinary Research Institute, Izatnagar, India

    Sonal Saxena

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Mondal, D.B., Velayudhan, J.M., Lekshman, A., Mandal, R.S.K., Raja, R., Kumar, N. (2022). Nanofabrication of Catechin-Loaded Alginate, Pectin, and Chitosan Polymeric Nanoparticles. In: Kumar, N., Kumar, V., Shrivastava, S., Gangwar, A.K., Saxena, S. (eds) Tissue Scaffolds. Springer Protocols Handbooks. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2425-8_31

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  • DOI: https://doi.org/10.1007/978-1-0716-2425-8_31

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