Abstract
In 1917, Johann Radon posed the question of whether the integral over a function with two variables along an arbitrary line can uniquely define that function such that this functional transformation can be inverted. He also solved this problem as a purely mathematical one, although he mentioned some relationships to the physical potential theory in the plane. Forty-six years later, A. M. Cormack published a paper with a title very similar to that by Radon yet still not very informative to the general reader, namely ‘Representation of a function by its line integrals’—but now comes the point: ‘with some radiological applications’. Another point is that the paper appeared in a journal devoted to applied physics. Says Cormack, ‘A method is given of finding a real function in a finite region of a plane given by its line integrals along all lines intersecting the region. The solution found is applicable to three problems of interest for precise radiology and radiotherapy’. Today we know that the method is useful and applicable to the solution of many more problems, including that which won a Nobel prize in medicine, awarded to A. M. Cormack and G. N. Hounsfield in 1979. Radon’s pioneering paper (1917) initiated an entire mathematical field of integral geometry. Yet it remained unknown to the physicists (also to Cormack, whose paper shared the very same fate for a long time). However, the problem of projection and reconstruction, the problem of tomography as we call it today, is so general and ubiquitous that scientists from all kinds of fields stumbled on it and looked for a solution-without, however, looking back or looking to other fields.
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References
Abramowitz, M. and Stegun, I. A. (1965). Handbook of Mathematical Functions. Dover.
Born, M. and Wolf E. (1975). Principles of Optics. Pergamon, Oxford, UK.
Bracewell, R. (1999). The Hankel Transform, 3rd edn. McGraw-Hill, New York.
Cormack, A. M. (1963). Representation of a function by its line integrals with some radiological applications. J. Appl. Phys. 34:2722–2727.
Cormack, A. M. (1964). Representation of a function by its line integrals with some radiological applications. II. J. Appl. Phys. 35:2908–2912.
Deans, S. R. (1979). Gegenbauer transforms via Radon transforms. Siam J. Math. Am. 10:577–585.
DeRosier, D. J. and Klug, A. (1968). Reconstruction of three-dimensional structures from electron micrographs. Nature 217:130–134.
Frank, J., Radermacher, M., Penczek, P., Zhu, J., Li, Y., Ladjadj, M. and Leith, A. (1996). Spider and web: processing and visualization of images in 3d electron microscopy and related fields. J. Struct. Biol. 116:190–199.
Gautschi, W., Golub, G. N. and Opfer, G. (1999). Application and Computation of Orthogonal Polynomials. Birkhaueser, Basel, Switzerland.
Gradshteyn, J. S. and Ryzhik, L. M. (1994). Tables of Integrals, Series and Products, 5th edn. Academic Press.
Helgason, S. (1980). The Radon Transform. Birkhäuser, Boston.
Herman, G. T. (1979). Image Reconstruction From Projections. Springer, Berlin.
Howard, J. (1988). Tomography and reliable information. JOSA 5:999–1014.
Lanzavecchia, S. and Bellon, P. L. (1998). Fast computation of 3D radon transform via a direct fourier method. Bioinformatics 14:212–216.
Lanzavecchia, S., Bellon, P. L. and Radermacher, M. (1999). Fast and accurate threedimensional reconstruction from projections with random orientations via radon transforms. J. Struct. Biol. 128:152–164.
Lanzavecchia, S., Cantele, F., Radermacher, M. and Bellon P. L. (2002). Symmetry embedding in the reconstruction of macromolecular assemblies via discrete radon transform. J. Struct. Biol. 17:259–272.
Lerche, I. and Zeitler, E. (1976). Projections, reconstructions and orthogonal functions. J. Math. Anal. Apppl. 56:634–649.
Lewitt, R. M. and Bates, R. H. T. (1978a). Image reconstruction from projections: I. General theoretical considerations. Optik 50:19–33.
Lewitt, R. M. and Bates, R. H. T. (1978b). Image reconstruction from projections: III. Projection completion methods (theory). Optik 50:189–204.
Lewitt, R. M., Bates, R. H. T. and Peters, T. M. (1978). Image reconstruction from projections: II. modified back-projection methods. Optik 50:85–109.
Nikiforov, A. F., Uvarov, V. B. and Suslov, S. S. (1992). Classical Orthogonal Polynomials of a Discrete Variable. Springer, New York
Pawlak, M. and Liao, S. X. (2002). On the recovery of a function on a circular domain. IEEE Trans. Inform. Theory 48:2736–2753.
Radermacher, M. (1994). Three-dimensional reconstruction from random projections: orientational alignment via radon transforms. Ultramicroscopy 53:121–136.
Radermacher, M. (1997). Radon transform technique for alignment and 3d reconstruction from random projections. Scanning Microsc. Int. Suppl.:169–176.
Radermacher, M., Ruiz, T., Wieczorek, H. and Gruber, G. (2001). The structure of the v(1)-atpase determined by three-dimensional electron microscopy of single particles. J. Struct Biol. 135:26–37.
Radon, J. (1917). Über die Bestimmung von Funktionen durch ihre Integralwerte längs gewisser Mannigfaltigkeiten. Ber. Verh. Sächs. Akad. 69:262–277.
Ramachandran, G.N. and Lakshiminarayanan, A.V. (1971). Three-dimensional reconstruction from radiographs and electron micrographs: application of convolutions instead of Fourier transforms. Proc. Natl Acad. Sci. USA 68:2236–2240.
Ruiz, T., Mechin, I., Br, J., Rypniewski, W., Kopperschlger, G. and Radermacher, M. (2003). The 10.8-structure of Saccharomyces cerevisiae phosphofructokinase determined by cryoelectron microscopy: localization of the putative fructose 6-phosphate binding sites. J. Struct. Biol. 143:124–134.
Smith, P. R. (1978). An integrated set of computer programs for processing electron micrographs of biological structures. Ultramicroscopy 3:153–160.
Smith, P. R., Peters, T.M. and Bates, R.H.T. (1973). Image reconstruction from finite numbers of projections. J. Phys. A 6:319–381.
Strichartz, R. S. (1982). Radon inversion—variation on a theme. Am. Math. Monthly 89:377–384.
Szegö, G. (1975). Orthogonal Polynomials. American Mathemeatics Society, Providence RI.
Vogel, R. H. and Provencher, S. W. (1988.) Three-dimensional reconstruction from electron micrographs of disordered specimens, II. Implementation and results. Ultramicroscopy 25:223–240.
Zeitler, E. (1974). The recostruction of objects from their projections. Optik 39:396–415.
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Zeitler, E. (2007). Reconstruction With Orthogonal Functions. In: Frank, J. (eds) Electron Tomography. Springer, New York, NY. https://doi.org/10.1007/978-0-387-69008-7_10
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