Abstract
A linkage between intracellular phenomena, involving the structuring of water, is described which associates the polarised multilayer theory with gel sol transitions. Intracellular K+ ions are revealed to form ion pairs with acid rich domains on static proteins, particularly F-actin. Such structures then create low density water clustering by a cooperative process that is able to influence other sites and so transfer information within the cell
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Bartell LS (1997) On possible interpretations of the anomalous properties of supercooled water. J Phys Chem 101:7573–7583
Cameron IL, Kanal KM, Keener CR, Fullerton GD (1997) A mechanistic view of the non-ideal osmotic and motional behavior of intracellular water. Cell Biol Int 21:99–113
Campolat M, Starr FW, Scala A, Sadr-Lahijany MR, Mishima O, Havlin S, Stanley HE (1998) Local structural heterogeneities in liquid water under pressure. Chem Phys Lett 294:9–12
Chaplin MF (2000) A proposal for the structuring of water. Biophys Chem 83:211–221
Chaplin MF (2005) Water Structure and Behavior. Available via http://www.lsbu.ac.uk/water
Cho CH, Urquidi J, Singh S, Park SC, Robinson GW (2002) Pressure effect on the density of water. J Phys Chem A 106:7557–7561
Clegg JS (1984) Interrelationships between water and cellular metabolism in Artemia cysts. XI. Density measurements. Cell Biophys 6:153–169
Collins KD (1995) Sticky ions in biological systems. Proc Natl Acad Sci USA 92:5553–5557
Collins KD (1997) Charge density-dependent strength of hydration and biological structure. Biophys J 72:65–76
Conway EJ (1957) Nature and significance of concentration relations of potassium and sodium ions in skeletal muscle. Physiol Rev 37:84–132
Ebner C, Onthong U, Probst M (2005) Computational study of hydrated phosphate anions. J Mol Liquids 118:15–25
Fournier P, Oelkers EH, Gout R, Pokrovski G (1998) Experimental determination of aqueous sodium-acetate dissociation constants at temperatures from 20 to 240 ^ˆC. Chem Geol 151:69–84
Garlid KD (2000) The state of water in biological systems. Int Rev Cytol 192:281–302
Halle B, Davidovic M (2003) Biomolecular hydration: From water dynamics to hydrodynamics. Proc Natl Acad Sci 100:12135–12140
Hazlewood CF (2001) Information forgotten or overlooked: Fundamental flaws in the conventional view of the living cell. Cell Mol Biol 47:959–970
Kern W (1948) Die aktivität der natriumionen in wäßrigen lösungen der salze mit polyvalenten säuren. Makromol Chemie 2:279–288
Khan A (2004) Theoretical studies of Na(H2O)+ 19-21 and K(H2O)+ 19-21 clusters: explaining the absence of magic peak for Na(H2O)+ 20. Chem Phys Lett 388:342–347
Langford VS, McKinley AJ, Quickenden TI (2001) Temperature dependence of the visible-near-infrared absorption spectrum of liquid water. J Phys Chem A 105:8916–8921
Ling GN (1962) A physical theory of the living state: the Association-Induction Hypothesis, Waltham, Mass: Blaisdell
Ling GN (1997) Debunking the alleged resurrection of the sodium pump hypothesis. Physiol Chem Phys Med NMR 29:123–198
Ling GN (2001) Life at the cell and below-cell level. The hidden history of a functional revolution in Biology, New York: Pacific Press
Ling GN (2003) A new theoretical foundation for the polarized-oriented multiplayer theory of cell water and for inanimate systems demonstrating long-range dynamic structuring of water molecules. Physiol Chem Phys Med NMR 35:91–130
Mershin A, Kolomenski AA, Schuessler HA, Nanopoulos DV (2004) Tubulin dipole moment, dielectric constant and quantum behavior: Computer simulations, experimental results and suggestions. BioSystems 77:73–85
Otterbein LR, Graceffa P, Dominguez R (2001) The crystal structure of uncomplexed actin in the ADP state. Science 293:708–711
Pollack GH (2001) Cells, gels and the engines of life: A new unifying approach to cell function, Washington: Ebner and Sons Publishers
Pollack GH (2003) The role of aqueous interfaces in the cell. Adv Colloid Interface Sci 103:173–196
Raichlin Y, Millo A, Katzir A (2004) Investigation of the structure of water using mid-IR fiberoptic evanescent wave spectroscopy. Phys Rev Lett 93:185703
Robinson GW, Cho CH, Urquidi J (1999) Isobestic points in liquid water: Further strong evidence for the two-state mixture model. J Chem Phys 111:698–702
Slosarek G, Heintz D, Kalbitzer HR (1994) Mobile segments in rabbit skeletal-muscle F-actin detected by H-1 nuclear magnetic resonance spectroscopy. FEBS Lett 351:405–410
Tongraar A, Rode BM (2004) Dynamical properties of water molecules in the hydration shells of Na+ and K+: Ab initio QM/MM molecular dynamics simulations. Chem Phys Lett 385:378–383
Trombetta G, Di Bona C, Grazi E (2005) The transition of polymers into a network of polymers alters per se the water activity. Int J Biol Macromol 35:15–18
Tuszyński JA, Brown JA, Hawrylak P (1998) Dielectric polarization, electrical conduction, information processing and quantum computation in microtubules. Are they plausible? Phil Trans Math Phys Eng Sc pp 356:1897–1926
Watterson JG (1997) The pressure pixel – unit of life? BioSystems 41:141–152
Wiggins PM (1996) High and low density water and resting, active and transformed cells. Cell Biol Int 20:429–435
Wiggins PM (2001) High and low density intracellular water. Cell Mol Biol 47:735–744
Wiggins PM (2002) Water in complex environments such as living systems. Physica A 314:485–491
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Springer
About this chapter
Cite this chapter
Chaplin, M.F. (2006). Information Exchange within Intracellular Water. In: Pollack, G.H., Cameron, I.L., Wheatley, D.N. (eds) Water and the Cell. Springer, Dordrecht. https://doi.org/10.1007/1-4020-4927-7_5
Download citation
DOI: https://doi.org/10.1007/1-4020-4927-7_5
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-4926-2
Online ISBN: 978-1-4020-4927-9
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)