Abstract
Making a brief history of what is named the ‘Memory of Water’ is obviously not an easy task. Trying to be as fair and accurate as possible is hampered by two main difficulties: 1) one of the main actors, Jacques Benveniste, recently passed away and 2) cutting edge science creates many controversies, especially with those whose lifetimes have been spent pursuing an unorthodox track. High dilution experiments and memory water theory may be related, and may provide an explanation for the observed phenomena. As Michel Schiff said: ‘the case of the memory of water may or not contribute to the knowledge about water structure. Perhaps the tentative interpretation Jacques suggested will finally have to be modified or even abandoned. Time and further research will tell, provided that one gives the phenomena a chance (Schiff, 1995, p 45)’
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References
Astumian RD, Weaver JC, Adair RK (1995) Rectification and signal averaging of weak electric fields by biological cells. Proc Natl Acad Sci USA 92:3740–3743
Bacq Z (1974) Les transmissions chimiques de l’influx nerveux. Villars G (ed), Paris, France
Banwell CN (1983) Fundamentals of Molecular Spectroscopy. McGraw-Hill Publ UK, pp 26–28
Belon P, Cumps J, Ennis M, Mannaioni PF, Sainte-Laudy J, Roberfroid M, Wiegant FA (1999)Inhibition of human basophil degranulation by successive histamine dilutions: results of a European multi-centre trial. Inflamm Res 48 Suppl 1:S17–S18
Belon P, Cumps J, Ennis M, Mannaioni PF, Roberfroid M,Sainte-Laudy J, Wiegant FA (2004)Histamine dilutions modulate basophil activation. Inflamm Res 53 (5):181–188
Benveniste J, Henson PM, Cochrane CG (1972) Leukocyte-dependent histamine release from rabbit platelets. The role of IgE, basophils, and a platelet-activating factor. J Exp Med 136:1356–1377
Benveniste J (1974) Platelet-activating factor, a new mediator of anaphylaxis and immune complex deposition from rabbit and human basophils. Nature 249:581–582
Benveniste J (1988) Dr Jacques Benveniste replies. Nature 334:291
Benveniste J, Davenas E, Ducot B, Cornillet B, Poitevin B, Spira A (1991) L’agitation de solutions hautement diluèes n’induit pas d’activitè biologique spècifique. Comptes-Rendus de l’Acadèmie des Sciences de Paris 312:461–466
Benveniste J, Bowllet C, Brink C, Labat C. 1983. The actions of PAF–acether on guinea.pig isolated heart preparations. Br J Pharmacol. 80(1):81–83
Blanchard JP, Blackman CF (1994) Clarification and application of an ion parametric resonance model for magnetic field interactions with biological systems. Bioelectromagnetics 15(3):217–238
Brown V, Ennis M (2001) Flow-cytometric analysis of basophil activation: inhibition by histamine at conventional and homeopathic concentrations. Inflamm Res 50(Suppl 2):S47–S48
Davenas E, Poitevin B, Benveniste J (1987) Effect of mouse peritoneal macrophages of orally administered very high dilutions of silica. Eur J Pharmacol 31, 135(3):313–319
Davenas E, Beauvais F, Amara J, Oberbaum M, Robinzon B, Miadonna A, Tedeschi A, Pomeranz B, Fortner P, Belon P, Sainte-Laudy J, Poitevin B, Benveniste J (1988) Human basophil degranulationtriggered by very dilute antiserum against IgE. Nature 333:816–818
Del Giudice E, Preparata G, Vitiello G (1988) Water as a free electric dipole laser. Phys Rev Lett 61:1085–1088
Elia V, Niccoli M (2004) New Physico-chemical properties of extremely diluted aqueous solutions. J Therm Anal Calorimetry 75:815–836
Endler PC, Pongratz W, Smith CW, Schulte J (1995) Non-molecular information transfer from thyroxine to frogs. Vet Hum Toxicol 37:259–263
Fesenko EE, Gluvstein AY (1995) Changes in the state of water,induced by radiofrequency electromagnetic fields. FEBS Lett 367:53–55
Frey AH (1993) Electromagnetic field interactions with biologicalsystems. FASEB J 7:272–281
Greenberg CS, Miraglia CC, Rickles FR, Shuman MA (1985) Cleavage of blood coagulation factor XIII and fibrinogen by thrombin during in vitro clotting. J Clin Invest 75(5):1463–1470
Gustaffson D, Elg M (2003) The pharmacodynamics and pharmacokinetics of the oral direct thrombin inhibitor ximelagatran and its active metabolite melagatran: A mini-review.Thromb Res 109 (Suppl 1):S9–S15
Hadji L, Arnoux B, Benveniste J (1991) Effect of dilute histamineon coronary flow of guinea-pig isolated heart. Inhibition by amagnetic field. FASEB J 1. 5:A–I583
Kim DH, Akera T, Kennedy RH (1983) Ischemia-induced enhancement of digitalis sensitivity in isolated guinea-pig heart. J Pharmacol Exp Ther 226(2):335–342
Leyravaud S, Benveniste J (1989) Regulation of cellular retention of PAF-acether by extracellular pH and cell concentration. Biochim Biophys Acta 1005:192–196
Maddox J, Randi J, Stewart WW (1988) High-dilution’experiments a delusion. Nature 334:287–290
Ninham BW, Boström M (2005) Building bridges between the physical and biological sciences. Cell Mol Biol (The scholars who talk to the wind, Thomas Y & Mentre P (eds)) in press
Novikov VV, Karnaukhov AV (1997) Mechanism of action of weak electromagnetic field on ionic currents in aqueous solutions of amino acids. Bioelectromagnetics 18:25–27
Pickard WF (1995) Trivial influences: A doubly stochastic Poisson process model permits the detection of arbitrarily small electromagnetic signal. Bioelectromagnetics 16(1):2–8 and 9–19
Poitevin B, Davenas E, Benveniste J (1988) In vitro immunological degranulation of human basophils is modulated by lung histamine and Apis mellifica. Br J Clin Pharmacol 25:439–444
Preparata G (1995) QED Coherence in Matter. Singapore: WorldScientific
Rey L (2003) Thermoluminescence of ultra high dilutions of lithium chloride and sodium chloride. Physica A 323:67–74
Schiff M (1995) The Memory of Water. Thorsons (ed), UK
Thomas Y, Schiff M, Belkadi L, Jurgens P, Kahhak L, Benveniste J (2000) Activation of human neutrophils by electronically transmitted phorbol-myristate acetate. Medical Hypotheses 54:33–39
Tsonga TY (1989) Deciphering the language of cells. Trends Biochem Sci 14:89–92
Vallee Ph, Lafait J, Mentré P, Monod MO, Thomas Y (2005) Effects of pulsed low frequency electromagnetic fields on water using photoluminescence spectroscopy: Role of bubble/water interface? J Chem Phys 122:114513–114521
Wiesenfeld K, Moss F (1995) Stochastic resonance and the benefits of noise: From ice ages to crayfish and SQUIDS. Nature 373:33–36
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Thomas, Y., Kahhak, L., Aissa, J. (2006). The physical nature of the biological signal, a puzzling phenomenon: the critical contribution of Jacques Benveniste. In: Pollack, G.H., Cameron, I.L., Wheatley, D.N. (eds) Water and the Cell. Springer, Dordrecht. https://doi.org/10.1007/1-4020-4927-7_17
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DOI: https://doi.org/10.1007/1-4020-4927-7_17
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