Abstract
Three rats with cannulae implanted in the posterior hypothalamic area and one nonimplant rat were tested in a conditioned suppression paradigm. During the acquisition phase of conditioned suppression, xylocaine hydrochloride was administered bilaterally via cannulae to two of the implant animals and an equal volume of normal saline was administered to the third animal. The xylocaine-injected animals required approximately twice the number of CS-UCS pairings as the saline-injected animal and five times the number of CS-UCS pairings as the normal control animal to acquire conditioned suppression. The maintenance of conditioned suppression was generally unaffected by xylocaine lesions.
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Dulle, M.E., D’encarnacao, P. & Long, C.J. The effect of reversible lesions in the posterior hypothalamus on conditioned suppression. Psychon Sci 17, 133–135 (1969). https://doi.org/10.3758/BF03336479
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DOI: https://doi.org/10.3758/BF03336479