Summary
Fox baits containing 50 mg praziquantel were distributed by aircraft in a 3000 km2 area of southwestern Germany from 1995 to 1999. 20 baits / km2 were initially distributed at intervals of six to twelve weeks. Starting from a prebaiting prevalence of 64 % (95 % C.I. 59–69), a level of 15 % (C.I. 10–21) was reached after 18 months. Further decreasing the frequency and discontinuing the bait distribution caused a surge to 55 % (C.I. 49–61) within 36 months. Other cestode species (Taenia spp., Mesocestoides spp.) showed similar responses, while the prevalence of ascarid nematodes did not decline during baiting. New infections of fox cubs with E. multilocularis, but not with other cestodes, drastically decreased after one year. Prevalences of fox helminths in an external control area remained stable. Our data suggest that repeated praziquantel treatment of free ranging foxes is suitable to reduce the prevalence of E. multilocularis in a large area.
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References
Cannon, R. M, Roe, R. T. (1990): Krankheitsüberwachung in Tierbeständen (Infection control in life stock) (deutsche Übersetzung und Bearbeitung von RJ Lorenz). AID, Bonn
Deplazes, P., Gloor, S., Hegglin, D., Romig, T. (2004): Wilderness in the city — the urbanization of Echinococcus multilocularis. Trends in Parasitology, 20: 77–84
Eckert, J., Deplazes, P., Craig, P. S., Gemmell, M. A, Gottstein, B., Heath, D., Jenkins, D. J., Kamiya, M., Lightowlers, M. (2001): Echinococcosis in animals: clinical aspects, diagnosis and treatment. In Eckert, J., Gemmell, M. A., Meslin, F. X., Pawlowsi, Z. S. (Eds.): WHO/OIE manual of echinococcosis in humans and animals: a public health problem of global concern. World Organisation for Animal Health, Paris, pp. 72–99
Gemmell, M. A., Lawson, J. R. (1986): Epidemiology and control of hydatid disease. In Thompson R. C. A. (Ed.): The biology of Echinococcus and hydatid disease. George Allen & Unwin, London, pp. 189–216
Gloor, S., Bontadina, F., Hegglin, D., Deplazes, D., Breitenmoser, U. (2001): The rise of urban fox populations in Switzerland. Mamm. Biol., 66: 155–164
Hansen, F., Thulke, H. H., Jeltsch, F. (2003): Simulationsmodelle zur Planung von Strategien in der Bekämpfung von Wildtiererkrankungen. Forum Geoökol., 14: 20–22
Hegglin, D., Ward, P. I., Deplazes, P. (2003): Anthelmintic baiting of foxes against urban contamination with Echinococcus multilocularis. Emerg. Infect. Dis., 9: 1266–1272
Ito, A., Romig, T., Takahashi, K. (2003): Perspective on control options for Echinococcus multilocularis with particular reference to Japan. Parasitology, 127: S159–S172
Jenkins, D. J., Romig, T., Thompson, R. C. A. (2005): Emergence/ re-emergence of Echinococcus spp. — a global update. Int. J. Parasitol., 35: 1205–1219
Loos-Frank, B. (1991): One or two intermediate hosts in the life cycle of Mesocestoides (Cyclophyllidea, Mesocestoididae)? Paraitol. Res., 77: 726–728
Pawlowski, Z. S., Eckert, J., Vuitton, D. A., Ammann, R. W., Kern, P. et al. (2001): Echinococcosis in humans: clinical aspects, diagnosis and treatment. In Eckert, J., Gemmell, M. A., Meslin, F. X., Pawlowsi, Z. S. (Eds.): WHO/OIE manual of echinococcosis in humans and animals: a public health problem of global concern. World Organisation for Animal Health, Paris, pp. 20–71
Romig, T., Kratzer, W., Kimmig P., Frosch, M., Gaus, W., Flegel, W. A., Gottstein, B., Lucius, R., Beckh, K., Kern, P. (1999a): An epidemiologic survey of human alveolar echinococcosis in southwestern Germany. Am. J. Trop. Med. Hyg., 61: 566–573
Romig, T., Bilger, B., Dinkel, A., Merli, M., Mackenstedt, U. (1999b): Echinococcus multilocularis in animal hosts: new data from western Europe. Helminthologia, 36: 185–191
Schelling, U., Frank, W., Will, R., Romig, T., Lucius, R. (1997): Chemotherapy with praziquantel has the potential to reduce the prevalence of Echinococcus multilocularis in wild foxes (Vulpes vulpes). Ann. Trop. Med. Parasitol., 91: 179–186
Schweiger, A., Ammann, R. W., Candinas, D., Clavien, P.-A., Eckert, J., Gottstein, B., Halkic, N., Muellhaupt, B., Prinz, B. M., Reichen, J., Tarr, P. E., Torgerson, P. R., Deplazes, P. (2007): Human alveolar echinococcosis after Fox Population Increase, Switzerland. Emerg. Infect. Dis. (Epub ahead of print)
Tackmann, K., Löschner, U., Mix, H., Staubach, C., Thulke, H.-H., Ziller, M., Conraths F. J. (2001): A field study to control Echinococcus multilocularis-infections of the red fox (Vulpes vulpes) in an endemic focus. Epidemiology and Infection, 127: 577–587
Thoma, D., Romig, T., Heinel, S., Janko, C., Schreiber, T., König, A., Dinkel, A., Mackenstedt, U. (2004): Small towns in Germany: Echinococcus multilocularis and fox biology. Int. Arch. Hydatidosis, 35: 136
Veit, P., Bilger, B., Schad, V., Schäffer, J., Frank, W., Lucius, R. (1995): Influence of environmental factors on the infectivity of Echinococcus multilocularis eggs. Parasitology, 110: 79–86
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Romig, T., Bilger, B., Dinkel, A. et al. Impact of praziquantel baiting on intestinal helminths of foxes in southwestern Germany. Helminthologia 44, 137–144 (2007). https://doi.org/10.2478/s11687-007-0021-9
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DOI: https://doi.org/10.2478/s11687-007-0021-9