SpringerLink
Log in

Determination of Sulfonamides in Milk by Cloud Point-Salting Out Extraction and Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry

  • Notes
  • Published:
Analytical Sciences Aims and scope Submit manuscript

Abstract

A method involving cloud point-salting out extraction (CPSOE) coupled with UHPLC-MS/MS was developed for the determination of eleven sulfonamides in milk. In this study, the type and concentration of the surfactant, de-emulsification condition, pH value, volume of n-butanol, equilibration temperature and time were optimized. For this developed method, the linear range of SAs was from 0.05 to 50 µg L–1, and the correlation coefficients were higher than 0.997. The average recoveries for SAs were from 61.32 to 91.67%, and the LOQs were less than 0.06 µg kg–1.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. X. Zuo, C. Qian, S. Ma, J. **ong, J. He, Z. Chen, Water Sei. Technol., 2019, 80, 507.

    Article  CAS  Google Scholar 

  2. S. Sachi, J. Ferdous, M. Sikder, S. Hussani, J. Adv. Vet. Anim. Res., 2019, 6, 315.

    Article  PubMed  PubMed Central  Google Scholar 

  3. National Food Safety Standard—Maximum Residue Limits for Veterinary Drugs in Foods Compilation prepared by Ministry of Agriculture of the People's Republic of China (MOA), http://english.agri.gov.cn/.

  4. Maximum Residue Limits (MRLs) List of Agricultural Chemicals in Foods Compilation prepared by The Japan Food Chemical Research Foundation (JFCRF), https://www.ffcr.or.jp/en/zanryu/the-japanese-positive/positive-list-system-glossary.html.

  5. Z. Wang, X. Wang, H. Tian, Q. Wei, B. Liu, G. Bao, M. Liao, J. Peng, X. Huang, L. Wang, Chemosphere, 2019, 250, 337.

    Article  Google Scholar 

  6. Y. Fujii, T. Kaga, K. Nishimura, Anal. Sei., 2019, 55, 961.

    Google Scholar 

  7. S. Lu, W. Liao, S. Chen, Anal. Sei., 2018, 34, 439.

    CAS  Google Scholar 

  8. Y. Wang, F. Hsieh, J. Wang, Y. Shu, Anal. Methods, 2019, 11, 4370.

    Article  CAS  Google Scholar 

  9. J. An, X. Wang, M. Ming, J. Li, N. Ye, R. Soe. Open Sei., 2018, 5, 172104.

    Article  Google Scholar 

  10. X. **ao, Q. Li, A. Xue, H. Chen, S. Li, Anal. Methods, 2016, 8, 571.

    Google Scholar 

  11. L. Kadzinski, R. Banasiuk, B. Banecki, LWT—Food Sei. Teehnol., 2018, 96, 7.

    Article  CAS  Google Scholar 

  12. K. Saridal and H.L. Ulusoy, Mieroehem. J., 2019, 150, 104170.

    Google Scholar 

  13. E. Heidarizadi and R. Tabaraki, Talanta, 2016, 148, 237.

    Article  PubMed  Google Scholar 

  14. G. Kojro and P. Wroczynski, J. Chromatogr. Sei., 2019, DOI: 10.1093/chromsci/bmz064.

    Google Scholar 

  15. G. Kojro, P.J. Rudzki, D.M. Pisklak, J. Giebultowicz, J. Chromatogr. A, 2019, 1591, 44.

    Article  CAS  PubMed  Google Scholar 

  16. J. Giebultowicz, G. Kojro, K. Bus-Kwasnik, P.J. Rudzki, R. Marszalek, A. Les, P. Wroczynski, J. Chromatogr. A, 2015, 1423, 39.

    Article  CAS  PubMed  Google Scholar 

  17. J. Giebultowicz, G. Kojro, R. Piotrowski, P. Kulakowski, P. Wroczynski, J. Pharm. Biomed. Anal., 2016, 128, 294.

    Article  CAS  PubMed  Google Scholar 

  18. N.I. Mohd, N.N.M. Zain, M. Raoov, S. Mohamad, R. Soe. Open Sei., 2018, 5, 171500.

    Article  CAS  Google Scholar 

  19. D. Wei, Z.H. Huang, S. Wang, Z. Guo, J. Li, Food Anal. Methods, 2016, 9, 427.

    Article  Google Scholar 

  20. P. Patidar and A. Bahadur, J. Mol. Liq., 2018, 249, 219.

    Article  Google Scholar 

  21. S. Kori, A. Parmar, J. Goyal, S. Sharma, J. Chromatogr. B, 2018, 1074, 129.

    Article  Google Scholar 

  22. X. Yu, L. Zhang, M. Liang, W. Sun, Chem. Eng. J., 2015, 279, 363.

    Article  CAS  Google Scholar 

  23. M. Üstün Özgür, M. Delmidan, J. AOAC Int., 2019, 102, 1241.

    Article  PubMed  Google Scholar 

  24. R. Kachangoon, J. Vichapong, R. Burakham, Y. Santaladchaiyakit, S. Srijaranai, Moleeules, 2018, 23, 1165.

    Article  Google Scholar 

  25. W. Zhang, C. Duan, M. Wang, Food Chem., 2011, 126, 779.

    Article  CAS  Google Scholar 

  26. N. Arroyo-Manzanares, L. Gâmiz-Gracia, A.M. Garcfa-Campana, Food Chem., 2014, 143, 459.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

This study was supported by The National Key Research and Development Program of China (grant number 2017YFC1601600).

Author information

Authors and Affiliations

  1. **angya School of Public Health, Central South University, Changsha, 410005, China

    Ze Li, Huilan Xu & Jianwu Wang

  2. Bei**g Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Bei**g Center for Disease Control and Prevention, Bei**g, 100013, China

    **g Zhang, Yunjia Yang & Yi Yang

Authors
  1. Ze Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. **g Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yunjia Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Huilan Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jianwu Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Yi Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Jianwu Wang or Yi Yang.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, Z., Zhang, J., Yang, Y. et al. Determination of Sulfonamides in Milk by Cloud Point-Salting Out Extraction and Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry. ANAL. SCI. 36, 1555–1559 (2020). https://doi.org/10.2116/analsci.20N013

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2116/analsci.20N013

Keywords

Search

Navigation