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Fig. 8 | BMC Cancer

Fig. 8

From: USP14 exhibits high expression levels in hepatocellular carcinoma and plays a crucial role in promoting the growth of liver cancer cells through the HK2/AKT/P62 axis

Fig. 8

Effects of USP14 on the proliferation, invasion, migration, and AKT/SQSTM1 pathway of liver cancer cells (A) Overexpression of HK2 partially eliminated the inhibitory effects of sh-USP14 on cell proliferation through the cell counting kit 8 (CCK8) assay. B Overexpression of HK2 partially eliminated the inhibitory effects of sh-USP14 on cell proliferation. C Overexpression of HK2 partially eliminated the inhibitory effects of sh-USP14 on cell invasion and migration through Transwell experiments. D Overexpression of HK2 can partially restore the inhibitory effect of USP14 on p-AKT and SQSTM1

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