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Fig. 7 | BMC Cancer

Fig. 7

From: USP14 exhibits high expression levels in hepatocellular carcinoma and plays a crucial role in promoting the growth of liver cancer cells through the HK2/AKT/P62 axis

Fig. 7

USP14 regulates autophagy by regulating the expression of SQSTM1/P62 through HK2 (A) In MHCC97H and HCCLM3 cells, the protein levels of SQSTM1/P62 decreased after knocking down USP14. B Detection of the interaction between SQSTM1/P62 and HK2 at the protein level through coimmunoprecipitation (CO-IP). C CO-IP experiments show that knocking down USP14 weakens the interaction between SQSTM1/P62 and HK2

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