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Obtaining and Properties of L-Aspartic Acid Solutions of Chitosan

  • Macromolecular Compounds and Polymeric Materials
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Abstract

Conditions for obtaining L-aspartic acid solutions of chitosan were considered: dissolution of the polymer with the formation of chitosan aspartate occurs in pH range of 3.6–3.8 at a minimum stoichiometric ratio of [acid]/[chitosan (−NH2)] ∼ 0.43. The hydrodynamic, electrochemical, optical and biological properties of aqueous solutions of chitosan aspartic acid salt are investigated. It has been established that macromolecules of polymeric salt exhibit properties of a polyelectrolyte with a partially compensated charge in an aqueous medium. Huggins constants and temperature viscosity coefficients were calculated, which indicate an increased rigidity of the chitosan macrochain in the studied solutions and deterioration in the polymer—solvent interaction with increasing temperature. Chitosan aspartate powders in the form of lamellar microparticles with fractal ordering were isolated. Low biocompatibility and antibacterial activity of the polymeric salt are demonstrated, which allows recommending the production of biomedical products on its basis.

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Authors and Affiliations

  1. Chernyshevskii Saratov National Research State University, Saratov, 410012, Russia

    T. N. Lugovitskaya, I. V. Zudina & A. B. Shipovskaya

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  1. T. N. Lugovitskaya
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  2. I. V. Zudina
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  3. A. B. Shipovskaya
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Correspondence to T. N. Lugovitskaya.

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Russian Text © The Author(s), 2020, published in Zhurnal Prikladnoi Khimii, 2020, Vol. 93, No. 1, pp. 90–99.

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Lugovitskaya, T.N., Zudina, I.V. & Shipovskaya, A.B. Obtaining and Properties of L-Aspartic Acid Solutions of Chitosan. Russ J Appl Chem 93, 80–88 (2020). https://doi.org/10.1134/S1070427220010097

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