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Indigenous Plants Demonstrating Effective Antioxidant Properties

  • PLANT PHYSIOLOGY
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Abstract

Increased production of antioxidant herbal supplements utilizing traditional medicinal plants has been attributed to a high margin of economic effectiveness, environmental friendliness, and accessibility. Current investigations determined the antioxidant properties of leaf and stem extracts of five plants, Oxalis corniculata, Argemone mexicana, Thevetia neriifolia, Acacia karoo and Cassia fistula using DPPH radical scavenging activity, Xanthine oxidase (XO) inhibition and Superoxide scavenging activity. Based on the individual extract activity, different binary formulations were prepared and assayed for their antioxidant properties to identify the most promising combination. The A. mexicana and A. karoo leaf extracts showed maximum DPPH activity while highest XO inhibition was induced by A. mexicana leaf extract (IC50 = 6.849 ± 1.502 µg/mL) followed by the T. neriifolia stem extract (IC50 = 10.366 ± 0.1.322 µg/mL). Superoxide (SO) scavenging effect of all the extracts was significantly higher in comparison to the control. The combinations of A. mexicana and A. karoo leaf extracts in 2 : 1 and 3 : 1 ratios; and that of C. fistula and A. karoo stem extracts exhibited synergistic antioxidant effects in comparison to the individual extracts. The antioxidant activity increased with the rise in proportion of A. mexicana leaf extract and C. fistula stem extract in the respective mixture. The study implicates the blend of these leaf and stem extracts as a promising candidate for use as natural antioxidant for the human health. Utilization of these plants in medicinal and nutritional functions can diminish the side effects caused by the overuse of synthetic antioxidants.

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Funding

This research was supported by Acharya Narendra Dev College, University of Delhi.

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Authors and Affiliations

  1. The Doon School, Mall Road, 248001, Dehradun, Uttarkhand, India

    Karmanyaraj Singh Yadav

  2. Department of Zoology, Acharya Narendra Dev College, University of Delhi, 110019, Kalkaji, New Delhi, India

    Roopa Rani Samal & Sarita Kumar

  3. Department of Zoology, Ramjas College, University of Delhi, 110007, Delhi, India

    Arunima Sahgal

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  1. Karmanyaraj Singh Yadav
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KSY and RRS conceived the idea, conducted the experiments and wrote the manuscript. SK designed and guided the experiments. RRS analysed the results and SK helped in the statistical analysis. All the authors were involved in the finalization of manuscript.

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Correspondence to Sarita Kumar.

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The authors declare that they have no conflicts of interest. This article does not contain any studies involving animals or human participants performed by any of the authors.

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Karmanyaraj Singh Yadav, Samal, R.R., Sahgal, A. et al. Indigenous Plants Demonstrating Effective Antioxidant Properties. Biol Bull Russ Acad Sci 48 (Suppl 3), S62–S72 (2021). https://doi.org/10.1134/S1062359022010162

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