Log in

Extracting Knowledge from Images of Meanders and Spirals in the Diagnosis of Patients with Parkinson’s Disease

  • SELECTED PAPERS OF THE 8th INTERNATIONAL WORKSHOP “IMAGE MINING. THEORY AND APPLICATIONS”
  • Published:
Pattern Recognition and Image Analysis Aims and scope Submit manuscript

Abstract

In this paper, the problem of diagnosing Parkinson’s disease based on handwritten drawings is investigated. Human-drawn spirals and meanders are used as images. A genetic fuzzy classifier is used as a diagnostic tool. This classifier is built using machine learning methods based on a discrete genetic algorithm. The multiobjective non-dominated sorting genetic algorithm was applied in the work. The diagnostic error, the number of terms, and the number of rules were used as objectives. Higher diagnostic accuracy was achieved compared to methods such as naive Bayes classifier, support vector machine and optimum-path forest. In addition, the fuzzy classifier extracts knowledge for the clinician, which makes it possible to understand causal relationships when making a diagnosis. This is achieved thanks to fuzzy rules of the IF-THEN type. These rules use the fuzzy terms “Small”, “Medium”, “Large” to evaluate the values of the features of the image.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Germany)

Instant access to the full article PDF.

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.

Similar content being viewed by others

REFERENCES

  1. I. Aouraghe, “A novel approach combining temporal and spectral features of Arabic online handwriting for Parkinson’s disease prediction,” J. Neurosci. Methods 339, 108727 (2010). https://doi.org/10.1016/j.jneumeth.2020.108727

    Article  Google Scholar 

  2. M. Belić, V. Bobić, M. Badža, N. Šolaja, M. Đurić-Jovičić, and V. S. Kostić, “Artificial intelligence for assisting diagnostics and assessment of Parkinson’s disease—A review,” Clin. Neurol. Neurosurg. 184, 105442 (2019). https://doi.org/10.1016/j.clineuro.2019.105442

    Article  Google Scholar 

  3. K. Deb, S. Agrawal, A. Pratap, and T. Meyarivan, “A fast and elitist multiobjective genetic algorithm: NSGA-II,” IEEE Trans. Evol. Comput. 6, 182–197. (2002). https://doi.org/10.1109/4235.996017

    Article  Google Scholar 

  4. D. J. Gelb, E. Oliver, and S. Gilman, “Diagnostic criteria for Parkinson disease,” Arch. Neurol. 56, 33–39 (1999). https://doi.org/10.1001/archneur.56.1.33

    Article  Google Scholar 

  5. Georgieva P., “Genetic fuzzy system for financial management,” Cybern. Inf. Technol. 18, 20–35 (2018). https://doi.org/10.2478/cait-2018-0025

    Article  MathSciNet  Google Scholar 

  6. H. He, Y. Bai, E. A. Garcia, and S. Li, “ADASYN: Adaptive synthetic sampling approach for imbalanced learning,” in IEEE Int. Joint Conf. on Neural Networks (IEEE World Congress on Computational Intelligence), Hong Kong, 2008 (IEEE, 2008), pp. 1322–1328. https://doi.org/10.1109/IJCNN.2008.4633969

  7. D. Impedovo and G. Pirlo, “Dynamic handwriting analysis for the assessment of neurodegenerative diseases: a pattern recognition perspective,” IEEE Rev. Biomed. Eng. 12, 209–220. (2019). https://doi.org/10.1109/RBME.2018.2840679

    Article  Google Scholar 

  8. D. Impedovo, G. Pirlo, G. Vessio, and M. T. Angelillo, “A handwriting-based protocol for assessing neurodegenerative dementia,” Cognit. Comput. 11, 576–586 (2019). https://doi.org/10.1007/s12559-019-09642-2

    Article  Google Scholar 

  9. C. Kotsavasiloglou, N. Kostikis, D. Hristu-Varsakelis, and M. Arnaoutoglou, “Machine learning-based classification of simple drawing movements in Parkinson’s disease,” Biomed. Signal Process. Control 31, 174–180 (2017). https://doi.org/10.1016/j.bspc.2016.08.003

    Article  Google Scholar 

  10. R. Lamba, T. Gulati, K. A. Al-Dhlan, and A. Jain, “A systematic approach to diagnose Parkinson’s disease through kinematic features extracted from handwritten drawings,” J. Reliab. Intell. Environ. 7, 253–262 (2011). https://doi.org/10.1007/s40860-021-00130-9

    Article  Google Scholar 

  11. J. Mei, C. Desrosiers, and J. Frasnelli, “Machine learning for the diagnosis of Parkinson’s disease: A review of literature,” Front. Aging Neurosci. 13, 633752 (2011). https://doi.org/10.3389/fnagi.2021.633752

    Article  Google Scholar 

  12. A. Nishihara, N. Masuyama, Y. Nojima, and H. Ishibuchi, “Michigan-Style Fuzzy Genetics-Based Machine Learning for Class Imbalance Data,” J. Jpn. Soc. Fuzzy Theory Intell. Inf. 33, 525–530 (2011). https://doi.org/10.3156/jsoft.33.1_525

    Article  Google Scholar 

  13. Y. Omozaki, N. Masuyama, Y. Nojima, and H. Ishibuchi, “Multiobjective fuzzy genetics-based machine learning for multi-label classification,” in IEEE Int. Conf. on Fuzzy Systems (FUZZ-IEEE), Glasgow, UK, 2020 (IEEE, 2020). https://doi.org/10.1109/FUZZ48607.2020.9177804

  14. A. Parziale, R. Senatore, A. D. Cioppa, and A. Marcelli, “Cartesian genetic programming for diagnosis of Parkinson disease through handwriting analysis: Performance vs. interpretability issues,” Artif. Intell. Med. 111, 101984 (2011). https://doi.org/10.1016/j.artmed.2020.101984

    Article  Google Scholar 

  15. C. R. Pereira, D. R. Pereira, F. A. Silva, C. Hook, S. Weber, L. A. M. Pereira, and J. Papa, “A step towards the automated diagnosis of Parkinson’s disease: Analyzing handwriting movements,” in IEEE 28th Int. Symp. on Computer-Based Medical Systems, Sao Carlos, Brazil, 2015 (IEEE, 2015), pp. 171–176. https://doi.org/10.1109/CBMS.2015.34

  16. C. R. Pereira, D. R. Pereira, F. A. Silva, J. Masieiro, S. Weber, C. Hook, and J. Papa, “A new computer vision-based approach to aid the diagnosis of Parkinson’s disease,” Comput. Methods Programs Biomed. 136, 79–88 (2016). https://doi.org/10.1016/j.cmpb.2016.08.005

    Article  Google Scholar 

  17. S. Rosenblum, M. Samuel, S. Zlotnik, I. Erikh, and I. Schlesinger, “Handwriting as an objective tool for Parkinson’s disease diagnosis,” J. Neurol. 260, 2357–2361 (2013). https://doi.org/10.1007/s00415-013-6996-x

    Article  Google Scholar 

  18. K. S. Sarin and I. A. Hodashinsky, “Bagged ensemble of fuzzy classifiers and feature selection for handwritten signature verification,” Comput. Opt. 43, 833–845 (2019). https://doi.org/10.18287/2412-6179-2019-43-5-833-845

    Article  Google Scholar 

  19. R. Senatore and A. Marcelli, “A paradigm for emulating the early learning stage of handwriting: performance comparison between healthy controls and Parkinson’s disease patients in drawing loop shapes,” Hum. Mov. Sci. 65, 89–101 (2019). https://doi.org/10.1016/j.humov.2018.04.007

    Article  Google Scholar 

  20. T. Y. Zhang and C. Y. Suen, “A fast parallel algorithm for thinning digital patterns,” Commun. ACM 27, 236–239 (1984). https://doi.org/10.1145/357994.358023

    Article  Google Scholar 

Download references

Funding

This research was funded by Ministry of Science and Higher Education of the Russian Federation, project number FEWM-2020–0042 (AAAA-A20–120111190016-9).

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to K. Sarin, I. Hodashinsky or M. Svetlakov.

Ethics declarations

The authors declare that they have no conflicts of interest.

Additional information

Konstantin Sarin graduated from Tomsk State University of Control Systems and Radioelectronics (TUSUR) in 2002 with a degree in “Automated information processing and control systems”, Associate Professor of the Department for Complex Information Security of Electronic Computing Systems in TUSUR. Research interests: fuzzy systems, data analysis, machine learning, and biometrics.

Ilya Hodashinsky was born in 1953, graduated from the Faculty of Control Systems, Novosibirsk Electrotechnical Institute (NETI) in 1975. Received the Cand. Sci. degree in 1984, the D.Sc. degree in 2004 from the TUSUR, Russia. Received the Professor title at the 2011. He is a Professor of TUSUR. His main research interests include the computational intelligence, fuzzy modeling, pattern recognition, knowledge discovery, and data mining. He is author and co-author of over 150 journal and conference papers as well as technical articles. Prof. Hodashinsky is a member of IEEE, IEEE Computational Intelligence Society.

Mikhail Svetlakov graduated from TUSUR in 2019 with a degree in 10.05.04 “Information and analytical security systems”, postgraduate student of TUSUR (09.06.01 “Informatics and Computer Engineering”), Junior Researcher employee of LSAUBS (TUSUR), Lecturer at the Faculty of Security (TUSUR). Research interests: computational intelligence, metaheuristic optimization methods, deep learning methods, clustering, fuzzy systems, and biometrics.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sarin, K., Hodashinsky, I. & Svetlakov, M. Extracting Knowledge from Images of Meanders and Spirals in the Diagnosis of Patients with Parkinson’s Disease. Pattern Recognit. Image Anal. 32, 658–664 (2022). https://doi.org/10.1134/S1054661822030385

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1054661822030385

Keywords:

Navigation