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Calcium hydroxyapatite in hydroxyapatite/graphene oxide/collagen nanohybrids

  • Synthesis and Properties of Inorganic Compounds
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Abstract

Interactions between calcium and phosphorus salts, graphene oxide (GO), and collagen (COL) in aqueous solutions have been studied in the CaCl2–(NH4)2HPO4–NH3–H2O–GO–COL system (25°C) using the solubility (residual concentrations) method and pH measurements. Syntheses were shown to yield composites comprising nanocrystalline calcium hydroxyapatite Ca10(PO4)6(OH)2) (HA), GO, and COL of empirical formula Ca10(PO4)6(OH)2 · xGO · yH2O · zCOL (x = 0.5, 1.0, or 2.0; y = 6.5–7.7; z = 3 or 5 wt %). Some physicochemical characteristics of synthesis products and the effects of the composite formulation on the crystallographic characteristics, sizes, and morphology of nanocrystalline hydroxyapatite (NCHA) were determined and some composition–structure–dispersion–property relationships in the HA/GO/COL composites have been analyzed using chemical analysis, X-ray powder diffraction, IR spectroscopy, thermogravimetry (TGA), differential scanning calorimetry (DSC), and electron microscopy.

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Authors and Affiliations

  1. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninskii pr. 31, Moscow, 119991, Russia

    N. A. Zakharov, Zh. A. Ezhova, E. M. Koval’ & N. T. Kuznetsov

  2. Tambov State Technical University, Tambov, Russia

    A. G. Tkachev

Authors
  1. N. A. Zakharov
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  2. Zh. A. Ezhova
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  3. E. M. Koval’
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  4. A. G. Tkachev
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  5. N. T. Kuznetsov
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Correspondence to N. A. Zakharov.

Additional information

Original Russian Text © N.A. Zakharov, Zh.A. Ezhova, E.M. Koval’, A.G. Tkachev, N.T. Kuznetsov, 2015, published in Zhurnal Neorganicheskoi Khimii, 2015, Vol. 60, No. 12, pp. 1606–1620.

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Zakharov, N.A., Ezhova, Z.A., Koval’, E.M. et al. Calcium hydroxyapatite in hydroxyapatite/graphene oxide/collagen nanohybrids. Russ. J. Inorg. Chem. 60, 1467–1480 (2015). https://doi.org/10.1134/S0036023615120268

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