Abstract
The history of discovery and study of the unique mummified brain of the 39 thousand cal. BP woolly mammoth fossil from Yakutian permafrost with special references to the big brain reconstruction method is provided. The preliminary description of the reconstracted gyri and sulci is described and paleoneurological perspectives are observed and discussed. The big brain of the woolly mammoth demonstrates the complicated patterns of the primary, seconds and tertiary gyrification, which could be potentially used for the comparative study of the extinct mammoth specimen and living representatives of Elephantidae and for searching cross-genus differences.
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REFERENCES
Aufderheide, A.C., The Scientific Study of Mummies, UK: Cambridge Univ. Press, 2003.
Boeskorov, G.G., Protopopov, A.V., Mashchenko, E.N., et al., New findings of unique preserved fossil mammals in the permafrost of Yakutia, Dokl. Biol. Sci., 2013, vol. 452, no. 4, pp. 291–295.
Vereschagin, N.K. and Michelson, V.M., Eds., Magadanskii mamontenok Mammuthus primigenius (Blumenbach) (Magadan Mammoth Calf Mammuthus primigenius (Blumenbach)), Leningrad: Nauka, 1981.
Garutt, V.E. and Tikhonov, A.N., Origin and systematics of the family Elephantidae (Gray, 1821) with special references to tribe Mammuthini Brookes, 1828, in Mammoth and Its Environments: 200 Years of Investigations, Rozanov, A.Y., Ed., Moscow: GEOS, 2001, pp. 47–70.
Kurepina, M.M., Animal Brain: Phisiological Research Methods, M.: Nauka, 1981.
Maschenko, E.N., Evolution of the elephants of the mammoth lineage in the Northern Caucasus (Russia) in the Pliocene–Pleistocene, Tr. Zool. Inst., Ross. Akad. Nauk, 2010, vol. 314, pp. 197–210.
Saveliev, S.V., Comparative Anatomy of the Nervous System of Vertebrates, Moscow: GEOTAR-MED, 2001.
Serdyuk, N.V., Potapova, O.R., Kharlamova, A.S., et al., New data on the internal organs of a frozen “Yukagir” bison mummy (Bison priscus Bojanus, 1827), Yakutia, Russia, Dokl. Biol. Sci., 2016, vol. 467, no. 1, pp. 89–92.
Benoit, J., Crumpton, N., Merigeaud, S., and Tabuce, R., A memory already like an elephants? The advanced brain morphology of the last common ancestor of Afrotheria (Mammalia), Brain Behav. Evol., 2013, vol. 81, pp. 154–169.
Benoit, J., A new method of estimating brain mass through cranial capacity in extinct proboscideans to account for the non-neural tissues surrounding their brain, J. Vertebr. Paleontol., 2015, vol. 35, no. 6, e991021.
Bock, W.J., Discussion: The Concept of Homology, Ann. N. Y. Acad. Sci., 1969, vol. 167, pp. 71–73.
Cozzi, B., Spagnoli, S., and Bruno, L., An overview of the central nervous system of the elephant through a critical appraisal of the literature published in the XIX and XX centuries, Brain Res. Bull., 2001, vol. 54, pp. 219–227.
Garutt, W.E., Gentry, A., and Lister, A.M., Mammuthus Brookes, 1828 (Mammalia, Proboscidea): proposed conservation, and Elephas primigenius Blumenbach, 1799 (currently Mammuthus primigenius): Proposed designation as the type species of Mammuthus, and designation of a neotype, Bull. Zool. Nomencl., 1990, vol. 47, pp. 38–44.
Gerszten, P.C. and Martinez, A.J., The neuropathology of South American mummies, Neurosurgery, 1995, vol. 36, pp. 756–761.
Hakeem, A.Y., Hof, P.R., Sherwood, C.C., et al., Brain of the African elephant (Loxodonta africana): Neuroanatomy from magnetic resonance images, Anat. Rec., Part A, 2005, vol. 287, pp. 1117–1127.
Haug, H., Brain sizes, surfaces, and neuronal sizes of the cortex cerebri: A stereological investigation of man and his variability and a comparison with some Mammals (primates, whales, marsupials, insectivores, and one elephant), Am. J. Anat., 1987, vol. 180, pp. 126–142.
Jacobs, B., Lubs, J., Hannan, M., et al., Neuronal morphology in the African elephant (Loxodonta africana) neocortex, Brain Struct. Funct., 2011, vol. 215, pp. 273–229.
Jerison, H.J., Evolution of the Brain and Intelligence, New York: Academic, 1973.
Johnson, J.I., Kirsch, J.A., Reep, R.L., and Switzer, R.C., Phylogeny through brain traits: more characters for the analysis of mammalian evolution, Brain Behav. Evol., 1994, vol. 43, no. 6, pp. 319–347.
Kappers, A.C.U., Huber, G.C., and Crosby, E.C., The Comparative Anatomy of the Nervous System of Vertebrates Including Man, New York: Macmillan, 1936.
Kharlamova, A., Saveliev, S., Kurtova, A., et al., Preserved brain of the woolly mammoth Mammuthus primigenius (Blum. 1799) from the Yakutian Permafrost, in Proc. V Int. Conf. on Mammoths and Their Relatives, May 5–12, 2014, Grevena & Siatista, Abstracts of Papers, Thessaloniki: Sch. Geol., Aristotle Univ. of Thessaloniki, 2014, vol. 102, pp. 80–81.
Kharlamova, A.S., Saveliev, S.V., Protopopov, A., et al., The mummified brain of a pleistocene Woolly mammoth (Mammuthus primigenius) compared to the brain of the extant African elephant (Loxodonta africana), J. Comp. Neurol., 2015, vol. 523, pp. 2326–2343.
Kharlamova, A.S., Saveliev, S.V., Kurtova, A.I., et al., Preserved Brain of the Woolly Mammoth (Mammuthus primigenius (Blumenbach 1799)) from the Yakutian Permafrost, Quat. Int., 2016, vol. 406, pp. 86–93.
Kim, M.J., Lee, I.S., Lee, B.H., et al., Human mummified brain from a medieval tomb with lime-soil mixture barrier of the Joseon Dynasty, Korea, Int. J. Osteoarchaeol., 2008, vol. 18, pp. 614–623.
Kirsch, J.A. and Johnson, J.I., Phylogeny through brain traits: trees generated by neural characters, Brain Behav. Evol., 1983, vol. 22, nos. 2–3, pp. 60–69.
Knudsen, S.K., Mørk, S., and Qen, E.O., A novel method for in situ fixation of whale brains, J. Neurosci. Methods, 2002, vol. 120, pp. 35–44.
Kreps, E.M., Avrova, N.F., Chebotareva, M.A., et al., Brain lipids in fossilized mammoths, Mammuthus primigenius, Comp. Biochem. Physiol., 1981, vol. 68, no. 1, pp. 135–140.
Kupsky, W.J., Marchant, G.H., Cook, K., and Shoshani, J., Morphologic analysis of the hippocampal formation in Elephas maximus and Loxodonta africana with comparison to that of human, Proc. 1st Int. Congr. ‘‘La Terra degli Elefanti (The World of Elephants),” Cavarretta, G., Gioia, P., Mussi, M., Palombo, M.R., Eds., Rome: Consiglio Nazionale delle Ricerche, 2001, pp. 643–647.
Lister, A.M., History and taxonomy of Eurasian mammoths, in The Proboscidea: Evolution and Palaeoecology of Elephants and Their Relatives, Shoshani, J. and Tassy, J., Eds., Oxford: Oxford Univ. Press, 1996, pp. 203–213.
Lister, A.M. and Sher A.V., The origin and evolution of the woolly mammoth, Science, 2001, vol. 294, pp. 1094–1097.
Lynnerup, N., Mummies, Am. J. Phys. Anthropol., 2007, vol. 134 (Suppl. 45), pp. 162–190.
Maglio, V.P., Origin and evolution of the Elephantidae, Trans. Am. Philos. Soc., 1973, vol. 63, no. 3.
Maixner, F., Overath, T., Linke, D., et al., Paleoproteomic study of the Iceman’s brain tissue, Cell. Mol. Life Sci., 2013, vol. 70, no. 19, pp. 3709–3722.
Manger, P.R., Pillay, P., Maseko, B.C., et al., Acquisition of brains from the African elephant (Loxodonta africana): Perfusion-fixation and dissection, J. Neurosci. Methods, 2009, vol. 179, no. 1, pp. 16–21.
Manger, P.R., Prowse, M., Haagensen M., and Hemingway, J., Quantitative analysis of neocortical gyrencephaly in African elephants (Loxodonta africana) and six species of cetaceans: Comparison with other mammals, J. Comp. Neurol., 2012, vol. 520, pp. 2430–2439.
Manger, P.R., Patzke, N., and Spocter, M.A., The evolutions of large brain size in mammals: the “over-700-gram clubquartet”, Brain Behav. Evol., 2013, vol. 82, pp. 68–78.
Maschenko, E.N., Individual development, biology and evolution of the woolly mammoth Mammuthus primigenius (Blumenbach, 1799), Cranium, 2002, vol. 19.
Maschenko, E.N., Potapova O.R., Boeskorov G.G., et al., Preliminary data on the new partial carcass of the woolly mammoth, Mammuthus primigenius from Yakutia, Russia, 72nd Annual Meeting of the Society of Vertebrate Paleontology, Taylor and Francis, 2012.
Maschenko, E.N., Potapova, O.R., Vershinina, A., et al., The Zhenya Mammoth (Mammuthus primigenius (Blum.)): Taphonomy, geology, age, morphology and ancient DNA of a 48 000 yr old frozen mummy from western Taimyr, Russia, Quat. Int., 2017, vol. 445, pp. 104–134.
Maseko, B.C., Spocter, M.A., Haagensen, M., and Manger P.R., Volumetric analysis of the African elephant ventricular system, Anat. Rec., 2011, vol. 294, pp. 1412–1417.
Maseko, B.C., Spocter, M.A., Haagensen, M., and Manger, P.R., Elephants have relatively the largest cerebellum size of mammals, Anat. Rec., 2012, vol. 295, pp. 661–727.
Maseko, B.C., Patzke, N., Fuxe, K., and Manger P.R., Architectural organization of the African elephant diencephalon and brainstem, Brain Behav. Evol., 2013, vol. 82, pp. 83–128.
Nedden, D., Wicke K., Knapp R., et al., New findings on the tyrolean “Ice Man”: archaeological and CT-body analysis suggest personal disaster before death, J. Archaeol. Sci., 1994, vol. 21, no. 6, pp. 809–818.
Nieuwenhuys, R., ten Donkelaar, H.J., and Nicholson, C., The Central Nervous System of vertebrates, Berlin: Springer-Verlag, 1998, vol. 3, pp. 1637–2097.
Orlov, J.A., Perunium ursogulo Orlov, a new gigantic extinct mustelid (a contribution to the morphology of the scull and brain and to the phulogeny of mustelidae), Acta Zool. 1948, Bd. XXIX.
Patzke, N., Spocter, M.A., Karlsson, KÆ., et al., In contrast to many other mammals, cetaceans have relatively small hippocampi that appear to lack adult neurogenesis, Brain Struct. Funct., 2015, vol. 220, pp. 361–383.
Pirlot, P. and Kamiya, T., Qualitative and quantitative brain morphology in the Sirenian Dugong dugong, J. Zool. Syst. Evol. Res., 1985, vol. 23, no. 2, pp. 147–155.
Previgliano, C.H., Ceruti, C., Reinhard, J., et al., Radiologic evaluation of the Llullaillaco mummies, Am. J. Roentgenol., 2003, vol. 181, no. 6, pp. 1473–1479.
Protopopov, A.V., Potapova, O., Kharlamova, A.S., et al., The Frozen Cave Lion (Panthera spelaea (Goldfuss, 1810)) Newborn Cubs from Eastern Siberia, Russia: The first data on early ontogeny of the extinct species, J. Vertebr. Paleontol., Program and Abstracts, 2016.
Radanov, S., Stoev, S., Davidov, M., et al., A unique case of naturally occurring mummification of human brain tissue, Int. J. Leg. Med.,1992, vol. 105, no. 3, pp. 173–175.
Reep, R.L. and O’Shea, T.J., Regional Brain Morphometry and Lissencephaly in the Sirenia, Brain Behav. Evol., 1990, vol. 35, pp. 185–194.
Rohrs, V.M. and Ebinger, P., How is cranial capacity related to brain volume in mammals?, Mamm. Biol., 2001, vol. 66, pp. 102–110.
Roth, G. and Dicke, U., Evolution of the brain and intelligence, Trends Cognit. Sci., 2005, vol. 9, no. 5, pp. 250–257.
Shoshani, J. et al., On the dissection of a female Asian elephant Elephas maximus maximus (Linnaeus, 1758) and data from other elephants, Elephant, 1982, vol. 2, no. 1, pp. 3–93.
Shoshani, J. and Tassy, P., Advances in proboscidean taxonomy and classification, anatomy and physiology, and ecology and behavior, Quat. Int., 2005, vol. 126–128, pp. 5–20.
Shoshani, J., Kupsky, W.J., and Marchant, G.H., Elephant brain, Part I: Gross morphology, functions, comparative anatomy, and evolution, Brain Res. Bull., 2006, vol. 70, pp. 124–157.
Stephan, H., Frahm, H., and Baron, G., New and revised data on volume of brain structures in insectivores and primates, Folia Primatol., 1981, vol. 35, pp. 1–29.
Thomas, H., Barnes, L., Takeuchi, G., and MacGillivray, R.A., Fossil brain cast of a Sperm Whale (Cetacea, Physeteridae) from the Monterey formation, Los Olivos, California, in Program Book and Abstracts the 69th Annual Meeting of the Society of Vertebrate Paleontology, Bristol, 2009, pp. 191A.
Tkocz, I., Bytzer, P., and Bierring, F., Preserved brains in medieval skulls, Am. J. Phys. Anthropol., 1979, vol. 5, pp. 197–202.
Welker, W.I. and Seidenstein, S., Somatic sensory representation in the cerebral cortex of the raccoon (Procyon lotor), J. Compo Neurol., 1959, vol. 111, pp. 469–501.
Welker, W., Why does cerebral cortex fissure and fold?, in Cerebral Cortex, Jones, E.G. and Peters, A., Eds., Boston, MA: Springer, 1990, vol. 8B.
Zilles, K., Armstrong, E., Moser, K.H., et al., Gyrification in the cerebral cortex of primates, Brain Behav. Evol., 1989, vol. 34, pp. 143–150.
Zimmerman, M.R. and Tedford, R.H., Histologic structures preserved for 21 300 yr, Science, 1976, vol. 194, pp. 183–184.
ACKNOWLEDGMENTS
We are grateful to the A. Protopopov and all colleagues from the Academy of Republic of Science Sakha (Yakutia), who have worked on the Yuka project. We are also thankful for E. Maschenko from the Borissiak Paleontological Institute for his comments and advises.
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Kharlamova, A.S., Pavlov, I.S. & Saveliev, S.V. Unique 39 Thousand Cal. BP Brain of the “Yuka” Mammoth Mummified Fossils: A History and Methods of the Examination: Paleoneurological Perspectives. Paleontol. J. 55, 1260–1269 (2021). https://doi.org/10.1134/S0031030121110034
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DOI: https://doi.org/10.1134/S0031030121110034