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Meta-Analysis of Randomized Clinical Trials on the Speed of Pulse Wave Propagation

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Abstract

A theoretical analysis of the literature data on the pulse-wave propagation velocity using a combination of electrocardiographic and photoplethysmographic signals was carried out. Its diagnostic value in medical practice lies in its use as a noninvasive method for measuring blood pressure, as well as for determining arterial stiffness. Some studies have shown a relationship between the velocity of pulse-wave propagation and risk factors for cardiovascular diseases. Pulse-wave propagation velocity is an early marker and predictor of cardiovascular risk in both people with normal blood pressure and people with hypertension; it is used as the “gold standard” in determining arterial stiffness; however, the issue of accuracy and automation of measuring the pulse-wave propagation velocity remains unresolved.

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Fig. 1.

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ACKNOWLEDGMENTS

The author is grateful to his scientific supervisors, N.K. Chemeris and A.A. Grinevich, for valuable advice in planning research and recommendations on the design of the article.

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This work was supported by ongoing institutional funding. No additional grants to carry out or direct this research were obtained.

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  1. Institute of Cell Biophysics, Russian Academy of Sciences, 142290, Pushchino, Moscow oblast, Russia

    B. G. Gharamyan

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Abbreviations: ECG, electrocardiography; BP, blood pressure; PWPV, pulse-wave propagation velocity; PWTT, pulse wave transit time; PPG, photoplethysmography; HR, heart rate.

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Gharamyan, B.G. Meta-Analysis of Randomized Clinical Trials on the Speed of Pulse Wave Propagation. BIOPHYSICS 68, 1053–1065 (2023). https://doi.org/10.1134/S0006350923060088

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