Extended Data Fig. 4: Effect of HMB-001 on normal platelet aggregation.
![Extended Data Fig. 4](http://media.springernature.com/full/springer-static/esm/art%3A10.1038%2Fs44161-023-00418-4/MediaObjects/44161_2023_418_Fig12_ESM.jpg)
Platelet rich plasma from healthy donors (n = 3) was incubated with 0 or 100 nM HMB-001 and activated with different activators while stirring at 900 rpm at 37 °C. Subsequent platelet aggregation was monitored with light transmission for 15 min. Shown are representative light transmission aggregometry traces in a single donor when activated with a) 5 µM ADP, b) 5 µM Epinephrine, c) 4 µg/mL Collagen, or d) 10 µM PAR-1 AP.