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Supplementary Figure 13: Distal genomic element clusters are associated with distinct anatomical locations in the develo** forebrain. | Nature Neuroscience

Supplementary Figure 13: Distal genomic element clusters are associated with distinct anatomical locations in the develo** forebrain.

From: Single-nucleus analysis of accessible chromatin in develo** mouse forebrain reveals cell-type-specific transcriptional regulation

Supplementary Figure 13

Displayed is the enrichment of clusters of open chromatin for enhancers that are active in distinct regions of the develo** forebrain (n = 95)47. As expected elements mainly associated with radial glia and excitatory neuron cell-types (Fig. 2e, K1,3,4) were enriched for pallial subregions, whereas inhibitory neuron associated elements (Fig. 2e, K9-11) were enriched in LGE and MGE regions. Clusters with less than 5 overlap** elements were excluded from the analysis. Binomial testing was used for statistical analysis. The p-values were not corrected. Anatomically annotated enhancers: n = 14647; open chromatin regions: K1: n = 880; K3: n = 1838; K4: n = 1015; K5: n = 1276; K9: n = 1042; K10: n = 1238; K11: n = 623.

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