Extended Data Fig. 5: Cellular and serological responses to vaccination among previously uninfected subjects.
From: Establishment and recall of SARS-CoV-2 spike epitope-specific CD4+ T cell memory
(a) Kinetics of anti-spike IgG titres after vaccine dose 1 and 2 (n = 10). (b) CCR7 and CD27 expression on TET751+ T cells at three weeks post-dose 1 or two weeks post-dose 2 in the BNT162b2 cohort (n = 7). Statistics assessed by Wilcoxon test (two-sided). (c) Longitudinal frequency of total activated (ICOS+CD38+) cTFH following BNT162b2 vaccination (n = 7). Closed circles, samples after dose 1; open circles, samples after dose 2. (d) Phenotype of TET751+ cTFH at three weeks post-dose 1 or one week post-dose 2 among the BNT162b2 cohort (n = 7).