Extended Data Fig. 4: Activation and expansion of TET236+ cells during primary vaccination.
From: Establishment and recall of SARS-CoV-2 spike epitope-specific CD4+ T cell memory
(a) Frequency of ICOS+CD38+ cells among the TET236+ population prior to vaccination, at week 3 following dose 1, or week 2 following dose 2. Statistics assessed by Friedman test with Dunn’s post-test comparing to baseline (two-sided; n = 10). (b) Frequency of TET236+ T cells (as % of the total CD4+ population) at baseline or following vaccine dose 1 or 2. Plots show TET236+ and TET751+ T cells for an individual with increases in TET236+ cells following vaccination.