Extended Data Fig. 3: Conventional T cell development is normal in the absence of BCL-6.
From: The transcription factor BCL-6 controls early development of innate-like T cells
a, FACS plots showing the expression of CD4 and CD8 (upper panel), and TCRβ (lower panel) in total thymocytes from the indicated mouse strains. b, Histograms showing the total number of the indicated thymocyte populations in control and Bcl6Δ/Δ mice. Graphs show the mean ± SEM. n = 5 independent experiments. c, Histograms showing the abundance of Tcra Vα14-Jα18 and Sh2d1a transcripts in control and Bcl6Δ/Δ sorted DP thymocytes. Graphs show the mean ± SEM. n = 3 independent experiments. d, Histograms showing the expression of CD1D, CD150, and LY108 in DP thymocytes from control and Bcl6Δ/Δ mice. These experiments were repeated three times with identical results. Statistical analysis was performed with two-tailed unpaired t-test.