Extended Data Fig. 4: Extended analyses of projection and interneuron cell type relationships across regions.

a, Normalized gene expression heatmaps of the neighbouring cell types for clusters within each metacluster. The clusters are sorted by increasing distance to the index metacluster (nearest at top), with the dotted horizontal line delineating the proximate neighbourhood (Methods). Marker genes are plotted to show the calibration of neighbourhoods to include only similar cell types. b, Extended ridge plots depicting the transcriptomic distance from selected regions’ projection and interneuron cell types to their proximate neighbourhoods, separating each neighbourhood into their CCF regions (Methods). The neurons are split into the relevant metacluster for each region.