A micropatterned human pluripotent stem cell-based developmental model was utilized to demonstrate the role of biophysical cues such as cell size and cytoskeletal contractile forces in directing patterning of neuroepithelial and neural plate border cells.
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Tewary, M., Zandstra, P.W. Mechanics-guided developmental fate patterning. Nature Mater 17, 571–572 (2018). https://doi.org/10.1038/s41563-018-0121-6
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DOI: https://doi.org/10.1038/s41563-018-0121-6
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