Correction to: Cell Death and Disease https://doi.org/10.1038/s41419-021-03413-4, published online 01 February 2021
In this article Fig. 4 has been updated:
Fig. 4: SNHG1 could directly bind to hnRNPL and regulate EMT.
A Hierarchical clustering of 1045 transcripts altered (≥1.5-fold change) in NC-treated cells and shRNA SNHG1-treated cells with three repeats. B, C KEGG analysis and differential genes GSEA enrichment analysis demonstrated that cell adhesion molecules are the potential targets of SNHG1 pathway. D Volcanic map analysis of differential genes. E The altered mRNA levels of genes were selectively confirmed by qRT-PCR in knockdown SNHG1. F SDS-PAGE silver staining of RNA pull-down protein samples showed a significant difference in protein band from 55 to 70 kDa. G Differential protein band mass spectrometry showed that the protein was hnRNPL. H The interaction possibilities of hnRNPL and SNHG1 were detected in RPIseq, and the results showed that hnRNPL could well bind with SNHG1 well (RPISeq). I Pull-down assays showed that biotinylated SNHG1 could retrieve hnRNPL in DU145 cells by western blot(flow-through was a input control). J RNA immunoprecipitation revealed that hnRNPL could also specifically bind to SNHG1. K, L The western blotting results after SNHG1 knockdown in DU145 and C4-2 cells showed that the expression level of hnRNPL did not change, while E-cad and Claudin-1 were significantly up-regulated, Vimentin, Slug and ZEB1 were significantly decreased. overexpression of SNHG1 showed an opposite effect of these protein in in DU145 and C4-2 cells. Error bars indicate means ± SD. ***P < 0.001, ****P < 0.0001.
The original article has been corrected.
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
About this article
Cite this article
Tan, X., Chen, Wb., Lv, Dj. et al. Correction: LncRNA SNHG1 and RNA binding protein hnRNPL form a complex and coregulate CDH1 to boost the growth and metastasis of prostate cancer. Cell Death Dis 15, 213 (2024). https://doi.org/10.1038/s41419-024-06561-5
Published:
DOI: https://doi.org/10.1038/s41419-024-06561-5
- Springer Nature Limited