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Point of care magnetic resonance neonatal neuroimaging applications and early imaging in infants under active therapeutic hypothermia: a perspective

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Abstract

As care of the most vulnerable infants in the neonatal intensive care unit (NICU) evolves, improved and real-time understanding of brain health becomes key. The availability of an in-NICU magnetic resonance imaging (MRI) scanner provides unique options to bedside care providers and researchers. We present our perspective on the 1-Tesla MRI unit in our NICU and its utilities and applications both in the clinical and research fields. We also discuss our experience with early and serial MRI in a cohort of infants with hypoxic-ischemic encephalopathy while undergoing therapeutic hypothermia, using a compatible cooling blanket and monitoring apparatus with special insight into the planning and organization between providers, and parental perspectives around early, detailed imaging.

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Fig. 1: Arrangement for in-NICU MRI while ongoing therapeutic hypothermia.

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Acknowledgements

We thank our research nurses Elizabeth Singh, Yvonne Sheldon, Tina Steele, and Deborah Cuddyer for their involvement and contribution throughout the work. We are grateful to all the parents who gave us their time, consideration and trust.

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Authors and Affiliations

  1. Division of Newborn Medicine, Department of Pediatrics, Brigham and Women’s Hospital, Boston, MA, USA

    Sriya Roychaudhuri, Yasemin Ersen, Mohamed El-Dib & Terrie Inder

  2. Division of Neonatal-Perinatal Medicine, University of British Columbia, Vancouver, BC, Canada

    Sriya Roychaudhuri

  3. Harvard Medical School, Boston, MA, USA

    Mohamed El-Dib & Terrie Inder

  4. Division of Neonatology, Children’s Hospital of Orange County and University of California, Irvine, Irvine, CA, USA

    Terrie Inder

Authors
  1. Sriya Roychaudhuri
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  2. Yasemin Ersen
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  4. Terrie Inder
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Contributions

SR and YE participated in research data acquisition, drafted the initial manuscript, and reviewed and revised the manuscript. MED designed the study, assisted with data acquisition, and reviewed and revised the manuscript. TEI conceptualized and designed the studies, helped to draft the initial manuscript, and reviewed and revised the manuscript. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.

Corresponding author

Correspondence to Sriya Roychaudhuri.

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Competing interests

Dr. Terrie E. Inder is a member of the Scientific Advisory Board for Aspect Imaging.

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Roychaudhuri, S., Ersen, Y., El-Dib, M. et al. Point of care magnetic resonance neonatal neuroimaging applications and early imaging in infants under active therapeutic hypothermia: a perspective. J Perinatol (2024). https://doi.org/10.1038/s41372-024-02033-y

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  • DOI: https://doi.org/10.1038/s41372-024-02033-y

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