Retraction to: Experimental & Molecular Medicine https://doi.org/10.1038/s12276-018-0133-y, published online 05 September 2018

The authors have retracted this article. After publication they repeated the experiments further increasing the expression of KCNMA1 but found that this did not activate the cGMP PKG signaling pathway. The authors now believe that the mechanism by which the KCNMA1 gene inhibits the cGMP PKG signaling pathway affecting the disease is not one-to-one regulation. All authors agree to this retraction.