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Pushing back the limits of electron cryomicroscopy

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A convergence of technical advances in electron cryomicroscopy will allow visualization of biomolecular assemblies, without crystals, at resolutions below 10 Å. Recent cryomicroscopic structures of papillomavirus and hepatitis B virus capsid provide case studies.

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Authors and Affiliations

  1. Max-Planck Institutfur Biochemie, D-82152, Martinsriedy, Germany

    Wah Chiu

  2. Verna and Mans McLean Department of Biochemistry, Baylor College of Medicine, Houston, TX, 77030

    Michael F. Schmid

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  1. Wah Chiu
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  2. Michael F. Schmid
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Chiu, W., Schmid, M. Pushing back the limits of electron cryomicroscopy. Nat Struct Mol Biol 4, 331–333 (1997). https://doi.org/10.1038/nsb0597-331

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