Supplementary Figure 8: TOE1 targets RNA Pol II snRNAs.

(a) Left: Cumulative plots of sequence reads of U4 and U6 snRNAs depicted as in Figure 4. Only reads terminating at position -4 or after are represented with shaded areas indicating positions within the mature snRNAs. Right: Bar graphs showing the percent of snRNA reads with 3’ tails. Error bars represent s.d., n = 3 independent experiments and p-values (Student’s two-tailed paired t-test) *P < 0.05. (b) Cumulative plots of sequence reads for snRNA 3’ end positions with all reads represented, including those truncated beyond position -4.