Abstract
Coupling the separation capabilities of capillary zone electrophoresis with the analytical specificity of mass spectrometry yields a tool for detecting levels of substances down to 10 attomoles.
This is a preview of subscription content, log in via an institution to check access.
References
Jorgenson, J.W. & Lukacs, K.D. Science 222, 266–272 (1984).
Jorgenson, J.W. & Lukacs, K.D. Analyt. Chem. 53, 1298–1302 (1981).
Lauer, H.H. & McManigill, D. Analyt. Chem. 58, 166–170 (1986).
Olivares, J.A., Nguyen, N.T., Yonker, C.R. & Smith, R.D. Analyt. Chem. 59, 1230–1232 (1987).
Thomson, B.A. & Iiribarne, J.V. J. chem. Phys. 71, 4451–4463 (1979).
Dole, M. et al. J. chem. Phys. 49, 2240–2249 (1968).
Whitehouse, C.M. Dreyer, R.N. Yamashita, M., & Fenn, J.B. Analyt. Chem. 57, 675–679 (1985).
Vestal, M.L. Mass Spectrom. Rev. 2. 447–480 (1986).
Cook, K.D. Mass Spectrom. Rev. 5, 467–519 (1986).
Smith, R.D., Olivares, J.A., Nguyen, H.T. & Udseth, H.R. Analyt. Chem., in the press.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Smith, R., Udseth, H. Capillary zone electrophoresis-MS. Nature 331, 639–640 (1988). https://doi.org/10.1038/331639a0
Issue Date:
DOI: https://doi.org/10.1038/331639a0
- Springer Nature Limited
This article is cited by
-
A brief history and spectroscopic analysis of soy isoflavones
Food Science and Biotechnology (2020)
-
A century of mass spectrometry: from atoms to proteomes
Nature Methods (2011)
-
Coupling of capillary electroseparation techniques with mass spectrometric detection
Analytical and Bioanalytical Chemistry (2007)