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Effect of calcium supplements on osteoporosis by using nuclear analytical techniques

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Abstract

Neutron activation analysis (NAA) and dual energy X-ray absorptiometry (DEXA) have been used to study the effects of different calcium supplements on osteoporosis, including calcium carbonate, calcium threonate, calcium gluconate, calcium lactate, calcium acetate and a traditional Chinese medicine. Animal test results showed that calcium carbonate, calcium gluconate, calcium acetate and the Chinese medicine notably increased osteoporotic rat's femoral bone mineral density (BMD). Also, calcium carbonate, calcium acetate and the Chinese medicine significantly increased osteoporotic rat's vertebral BMD. But calcium L-threonate and calcium lactate had no such effects. Calcium gluconate, calcium acetate and the Chinese medicine improved the bone mechanical intensity of osteoporotic rats. The results of NAA showed that the loss of elements in spongy bones was more seriously than that in compact bone and was difficult to be improved.

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Authors and Affiliations

  1. Laboratory of Nuclear Analytical Techniques, Institute of High Energy Physics, Chinese Academy of Sciences, P. O. Box 918, Bei**g, 100039, P.R. China

    Sumin Hu, Xueying Mao, Zhifang Chai & Hong Ouyang

  2. Bei**g University of Chinese Medicine, P. O. Box 68, Bei**g, 100029, P.R. China

    Hongfei Wang & Jianjun Zhang

Authors
  1. Sumin Hu
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  2. Xueying Mao
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  3. Zhifang Chai
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  4. Hongfei Wang
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  5. Hong Ouyang
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  6. Jianjun Zhang
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Hu, S., Mao, X., Chai, Z. et al. Effect of calcium supplements on osteoporosis by using nuclear analytical techniques. Journal of Radioanalytical and Nuclear Chemistry 259, 369–373 (2004). https://doi.org/10.1023/B:JRNC.0000020902.83902.64

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  • DOI: https://doi.org/10.1023/B:JRNC.0000020902.83902.64

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