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Polymer Based Biofilms: Development and Clinical Application in Medical Science

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Abstract

The utilization of polymers as biomaterials has greatly impacted the advancement of modern medicine and healthcare practice, there are currently thousands of medical devices, diagnostic products, and disposables on the market. Based on the data of modern scientific literature, the requirements for medicinal films are outlined, and their classification is given. Approaches to the choice of active and auxiliary substances in the process of develo** new film formulations are described. Novel advancement technology-based Biopolymer Based Biofilms were discussed in detail, i.e. PEGylation of surface, Layer-by-layer (LBL) biofilms, and Nanostructured composite films. The prospects of using films in surgery, wound healing, dentistry, ophthalmology, and dermatology are shown. In this manuscript, we conclude with an overview of the different natural and synthetic polymers that are currently being used and their properties, main aspects of the technological process for the preparation of films are described. as well as new developments in their synthesis and the ways of rational application of films in medical practice have been highlighted. The current chapter also highlights the method of film formation by various technic with their relevant application in the biomedical aspect.

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Authors and Affiliations

  1. Chandra Shekhar Singh College of Pharmacy, Kaushambi, U.P., India

    Roohi Kesharwani, Rinki Yadav & Shikha Kesharwani

  2. Northeast Frontier Railway Hospital, Goalpara, Assam, India

    Surendra Tripathy

  3. Department of Pharmacy, Government Polytechnic Jaunpur, Jaunpur, U.P., India

    Pankaj Verma & Dilip K. Patel

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  1. Roohi Kesharwani
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Kesharwani, R., Yadav, R., Kesharwani, S. et al. Polymer Based Biofilms: Development and Clinical Application in Medical Science. Biomedical Materials & Devices 2, 275–287 (2024). https://doi.org/10.1007/s44174-023-00114-8

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