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Cyanides from the Seeds of Sinapis alba

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Abstract

A phytochemical investigation of the seeds of Sinapis alba L., Brassicaceae, resulted in the isolation of two undescribed cyanide compounds, 4-hydroxy-3-((4-hydroxyphenyl)methyl) phenylacetonitrile and 4-hydroxy-3-((4-hydroxy-3-((4-hydroxyphenyl)methyl)phenyl)methyl) phenylacetonitrile. Their chemical structures were elucidated by NMR and HR-ESI–MS analyses.

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Funding

This work was funded by the Project of the Shandong Province Key Research and Development Program (2021CXGC010511), the project of Shandong postgraduate education quality curriculum (SDYKC21051), and the innovation training program for college students of Shandong University of Traditional Chinese Medicine (2021047).

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Contributions

LW and DGK conducted experiments, data analysis, and manuscript writing. BS, JLT, and WZ participated in literature search and data analysis. ZHT provided nuclear magnetic data. WLC, JL, DW, and HLZ reviewed the manuscript. All authors read and approved the final version of the manuscript.

Corresponding author

Correspondence to Honglei Zhou.

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The authors declare no competing interests.

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Wang, L., Kong, D., Sang, B. et al. Cyanides from the Seeds of Sinapis alba. Rev. Bras. Farmacogn. 32, 1021–1024 (2022). https://doi.org/10.1007/s43450-022-00323-0

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  • DOI: https://doi.org/10.1007/s43450-022-00323-0

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