Log in

Efficacy of silver diamine fluoride and sodium fluoride in inhibiting enamel erosion: an ex vivo study with primary teeth

  • Original Scientific Article
  • Published:
European Archives of Paediatric Dentistry Aims and scope Submit manuscript

Abstract

Purpose

To assess the efficacy of silver diamine fluoride (SDF) and sodium fluoride (NaF) in inhibiting enamel erosion in primary teeth.

Methods

80 primary canine teeth were immersed for 24 h in 2% NaF, 10% SDF, or distilled water. Afterward, some of them underwent a 10-min acid challenge using either 1% or 10% citric acid while others did not. Specimens selected for negative controls were immersed in distilled water but not exposed to the acids, whereas those selected for positive controls were not only immersed in distilled water, but also exposed to the acids. Following, 3-mL samples were collected for calcium and phosphorus analysis by an atomic emission spectrometer.

Results

1% acid caused higher phosphorus loss in the positive control group than in the others (no differences between them). Regarding 10% acid, the SDF group showed lower phosphorus loss compared to the positive control and NaF groups. From calcium loss analysis, SDF and NaF groups presented no significant difference when compared to the positive control groups after both acidic challenges.

Conclusion

Considering phosphorus loss values, 10% SDF seems to be effective in inhibiting enamel erosion after 1% and 10% citric acid challenges, whereas 2% NaF only after 1% citric acid challenge. Regarding calcium loss values, both fluoride agents seem to have no impact on inhibiting enamel erosion after 1% and 10% citric acid challenges.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Al-Mashhadani A, Plygkos I, Bozec L, Rodriguez JM. Three-dimensional in vitro measurements of tooth wear using fluoridated dentifrices. Aust Dent J. 2016;61:304–9.

    Article  Google Scholar 

  • Baelum V, Van Palenstein HW, Hugoson A, Yee R, Fejerskov O. A global perspective on changes in the burden of caries and periodontitis: Implications for dentistry. J Oral Rehabil. 2007;34:872–906.

    Article  Google Scholar 

  • Chunmuang S, Jitpukdeebodintra S, Chuenarrom C, Benjakul P. Effect of xylitol and fluoride on enamel erosion in vitro. J Oral Sci. 2007;49:293–7.

    Article  Google Scholar 

  • Colombo M, Dagna A, Moroni G, Chiesa M, Poggio C, Pietrocola G. Effect of different protective agents on enamel erosion: an in vitro investigation. J Clin Exp Dent. 2019;11:e113–e138.

    Article  Google Scholar 

  • Ganss C, Klimek J, Schäffer U, Spall T. Effectiveness of two fluoridation measures on erosion progression in human enamel and dentine in vitro. Caries Res. 2001;35:325–30.

    Article  Google Scholar 

  • Hannig C, Hamkens A, Becker K, Attin R, Attin T. Erosive effects of different acids on bovine enamel: Release of calcium and phosphate in vitro. Arch Oral Biol. 2005;50:541–52.

    Article  Google Scholar 

  • Hjortsjö C, Jonski G, Young A, Saxegaard E. Effect of acidic fluoride treatments on early enamel erosion lesions—A comparison of calcium and profilometric analyses. Arch Oral Biol. 2010;55:229–34.

    Article  Google Scholar 

  • Hughes JA, West NX, Addy M. The protective effect of fluoride treatments against enamel erosion in vitro. J Oral Rehabil. 2004;31:357–63.

    Article  Google Scholar 

  • Jaeggi T, Lussi A. Prevalence, incidence and distribution of erosion. Monogr Oral Sci. 2014;25:55–73.

    Article  Google Scholar 

  • Joshi M, Joshi N, Kathariya R, Prabhakar A, Raikar S. Techniques to evaluate dental erosion: a systematic review of literature. J Clin Diagnostic Res. 2016;10:1–7.

    Article  Google Scholar 

  • Kreulen CM, Van’T Spijker A, Rodriguez JM, Bronkhorst EM, Creugers NHJ, Bartlett DW. Systematic review of the prevalence of tooth wear in children and adolescents. Caries Res. 2010;44:151–9.

    Article  Google Scholar 

  • Larsen MJ. Prevention by means of fluoride of enamel erosion as caused by soft drinks and orange juice. Caries Res. 2001;35:229–34.

    Article  Google Scholar 

  • Larsen MJ, Richards A. Fluoride is unable to reduce dental erosion from soft drinks. Caries Res. 2002;36:75–80.

    Article  Google Scholar 

  • Llodra JC, Rodriguez A, Ferrer B, Menardia V, Ramos T, Morato M. Efficacy of silver diamine fluoride for caries reduction in primary teeth and first permanent molars of schoolchildren: 36-Month clinical trial. J Dent Res. 2005;84:721–4.

    Article  Google Scholar 

  • Lussi A, Buzalaf MAR, Duangthip D, Anttonen V, Ganss C, João-Souza SH, et al. The use of fluoride for the prevention of dental erosion and erosive tooth wear in children and adolescents. Eur Arch Paediatr Dent. 2019;20:517–27.

    Article  Google Scholar 

  • Mohammadi N, Far MHF. Effect of fluoridated varnish and silver diamine fluoride on enamel demineralization resistance in primary dentition. J Indian Soc Pedod Prev Dent. 2018;36:257.

    Article  Google Scholar 

  • Olivan SRG, Sfalcin RA, Fernandes KPS, Ferrari RAM, Horliana ACRT, Motta LJ, et al. Preventive effect of remineralizing materials on dental erosion lesions by speckle technique: an in vitro analysis. Photodiagnosis Photodyn Ther. 2020;29:101655.

    Article  Google Scholar 

  • Patel MV, Fox JL, Higuchi WI. Effect of acid type on kinetics and mechanism of dental enamel demineralization. J Dent Res. 1987;66:1425–30.

    Article  Google Scholar 

  • Pitts NB, Zero DT, Marsh PD, Ekstrand K, Weintraub JA, Ramos-Gomez F, et al. Dental caries. Nat Rev Dis Prim. 2017;3:17030.

    Article  Google Scholar 

  • Rees J, Loyn T, Chadwick B. Pronamel and tooth mousse: an initial assessment of erosion prevention in vitro. J Dent. 2007;35:355–7.

    Article  Google Scholar 

  • Rølla G, Ogaard B, de A Cruz R. Clinical effect and mechanism of cariostatic action of fluoride-containing toothpastes: a review. Int Dent J. 1991;41:171–4.

    PubMed  Google Scholar 

  • Rølla G, Øsard B, de Almeida CR. Topical application of fluorides on teeth: new concepts of mechanisms of interaction. J Clin Periodontol. 1993;20:105–8.

    Article  Google Scholar 

  • Salas MMS, Nascimento GG, Huysmans MC, Demarco FF. Estimated prevalence of erosive tooth wear in permanent teeth of children and adolescents: an epidemiological systematic review and meta-regression analysis. J Dent. 2015;43:42–50.

    Article  Google Scholar 

  • Schlueter N, Ganss C, Mueller U, Klimek J. Effect of titanium tetrafluoride and sodium fluoride on erosion progression in enamel and dentine in vitro. Caries Res. 2007;41:141–5.

    Article  Google Scholar 

  • Schlueter N, Jaeggi T, Lussi A. Is dental erosion really a problem? Adv Dent Res. 2012;24:68–71.

    Article  Google Scholar 

  • Shitsuka C, Ibuki FK, Nogueira FN, Mendes FM, Bönecker M. Assessment of oxidative stress in saliva of children with dental erosion. Einstein (Sao Paulo). 2018;16:eAO4203.

    Article  Google Scholar 

  • Sorvari R, Kiviranta I, Luoma H. Erosive effect of a sport drink mixture with and without addition of fluoride and magnesium on the molar teeth of rats. Eur J Oral Sci. 1988;96:226–31.

    Article  Google Scholar 

  • Sorvari R, Meurman JH, Alakuijala P, Frank RM. Effect of fluoride varnish and solution on enamel erosion in vitro. Caries Res. 1994;28:227–32.

    Article  Google Scholar 

  • Stookey GK. Critical evaluation of the composition and use of topical fluorides. J Dent Res. 1990;69:805–12.

    Article  Google Scholar 

  • ten Cate JM, Featherstone JDB. Mechanistic aspects of the interactions between fluoride and dental enamel. Crit Rev Oral Biol Med. 1991;2:283–96.

    Article  Google Scholar 

  • Van Rijkom H, Ruben J, Vieira A, Huysmans MC, Truin GJ, Mulder J. Erosion-inhibiting effect of sodium fluoride and titanium tetrafluoride treatment in vitro. Eur J Oral Sci. 2003;111:253–7.

    Article  Google Scholar 

  • Vieira A, Ruben JL, Huysmans MCDNJM. Effect of titanium tetrafluoride, amine fluoride and fluoride varnish on enamel erosion in vitro. Caries Res. 2005;39:371–9.

    Article  Google Scholar 

  • Vieira A, Jager DHJ, Ruben JL, Huysmans MCDNJM. Inhibition of erosive wear by fluoride varnish. Caries Res. 2007;41:61–7.

    Article  Google Scholar 

  • Zini A, Krivoroutski Y, Vered Y. Primary prevention of dental erosion by calcium and fluoride: a systematic review. Int J Dent Hyg. 2014;12:17–24.

    Article  Google Scholar 

Download references

Funding

None.

Author information

Authors and Affiliations

Authors

Contributions

All authors have made substantive contribution to this study and/or manuscript, and all have reviewed the final paper prior to its submission.

Corresponding author

Correspondence to L. F. Palma.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethics approval

Research Ethics Committee of Universidade Cruzeiro do Sul (Protocol #084/06).

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

da Cunha, W.A., Palma, L.F., Shitsuka, C. et al. Efficacy of silver diamine fluoride and sodium fluoride in inhibiting enamel erosion: an ex vivo study with primary teeth. Eur Arch Paediatr Dent 22, 387–392 (2021). https://doi.org/10.1007/s40368-020-00559-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40368-020-00559-1

Keywords

Navigation