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Manage idiopathic hypersomnia with a combination of non-pharmacological and pharmacological treatments

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Abstract

Idiopathic hypersomnia (IH) is a rare slee** disorder that is difficult to diagnose, and little is known about its pathophysiology. A defining symptom of IH is excessive daytime sleepiness, which can manifest as narcolepsy-like episodes or as continuous sleepiness. Other symptoms of IH includes sleep inertia and cognitive impairment. Currently, calcium, magnesium, potassium and sodium oxybates is the only FDA approved pharmacological treatment option in the management of IH. Off-label treatment options are recommended by guidelines, with many also being used for the management of narcolepsy.

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Correspondence to Arnold Lee.

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The preparation of this review was not supported by any external funding.

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A Lee is a salaried employee of Adis International Ltd/Springer Nature and declares no relevant conflicts of interest. All authors contributed to this article and are responsible for its content.

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Lee, A. Manage idiopathic hypersomnia with a combination of non-pharmacological and pharmacological treatments. Drugs Ther Perspect 39, 378–381 (2023). https://doi.org/10.1007/s40267-023-01028-7

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  • DOI: https://doi.org/10.1007/s40267-023-01028-7

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