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Modeling and Simulation of Scaffolds in Varied Conditions Using CAD and Medical Images

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Abstract

When it comes to research methods, bone tissue engineering (BTE) has reached a certain level of maturity. As a result, modeling and simulation of BTE procedures and phenomena have been shown to be an exceptional method of assessment in the phases leading up to architecture and validation of the proposed experiments in vitro and in vivo models in a series of papers. These contributions to BTE modeling and simulation are reviewed. Simulations in silico experiment review study for BTE are categorized into the following categories: (1) modeling of physical phenomena (CAD based and medical image based) and finite element method, (2) structural complexity in scaffolding and optimization, (3) various simulation condition of scaffold. Simulation and distinct modeling perspectives are the restricted scope of the paper, which focuses on CAD-based and medical image-based finite element analysis model of scaffolds. Two important findings were drawn at the result of the article: first, the extraordinary possibilities and economic implications that in silico experiment simulation provides in BTE, and second, the importance of collaborative practice that will further substantiate quantifiable and structural method proposed in BTE.

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Ansari, A.I., Sheikh, N.A. Modeling and Simulation of Scaffolds in Varied Conditions Using CAD and Medical Images. J. Inst. Eng. India Ser. C 104, 861–878 (2023). https://doi.org/10.1007/s40032-023-00960-x

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