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Magenkarzinom — Interventionelle Therapie

Vollständige Resektion Voraussetzung für entscheidende Prognoseverbesserung

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Beim chirurgischen Management des Magenkarzinoms ist die vollständige chirurgische Resektion des Primarius, entsprechender Lymphknotenstationen, mitbefallener Organe und gegebenenfalls des Peritoneums nach wie vor unerlässliche Voraussetzung für eine entscheidende Prognoseverbesserung. Die Wahl des chirurgischen Therapieverfahrens ist abhängig von Tumorstadium und -lokalisation.

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Literatur

  1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians. 2018;68(6):394–424.

    Google Scholar 

  2. Leung WK, Wu MS, Kakugawa Y, Kim JJ, Yeoh KG, Goh KL, et al. Screening for gastric cancer in Asia: current evidence and practice. Lancet Oncol. 2008;9(3):279–87.

    Article  Google Scholar 

  3. Sugano K. Screening of gastric cancer in Asia. Best practice & research Clinical gastroenterology. 2015;29(6):895–905.

    Article  Google Scholar 

  4. Song Z, Wu Y, Yang J, Yang D, Fang X. Progress in the treatment of advanced gastric cancer. Tumor Biology. 2017;39(7):1010428317714626.

    PubMed  Google Scholar 

  5. Cascinu S, Cancer ObotIGftSoDT, Labianca R, Cancer ObotIGftSoDT, Barone C, Cancer ObotIGftSoDT, et al. Adjuvant Treatment of High-Risk, Radically Resected Gastric Cancer Patients With 5-Fluorouracil, Leucovorin, Cisplatin, and Epidoxorubicin in a Randomized Controlled Trial. JNCI: Journal of the National Cancer Institute. 2007;99(8):601–7.

    Article  CAS  Google Scholar 

  6. Wanebo HJ, Kennedy BJ, Chmiel J, Steele G, Jr., Winchester D, Osteen R. ACancer of the stomach. patient care study by the American College of Surgeons. Ann Surg. 1993;218(5):583–92.

    Article  CAS  Google Scholar 

  7. Fuchs CS, Mayer RJ. Gastric carcinoma. N Engl J Med. 1995;333(1):32–41.

    Article  CAS  Google Scholar 

  8. Amin MB, Edge SB. AJCC cancer staging manual: Springer; 2017.

    Book  Google Scholar 

  9. Yoshida S, Saito D. Gastric premalignancy and cancer screening in high-risk patients. The American journal of gastroenterology. 1996;91(5):839–43.

    CAS  PubMed  Google Scholar 

  10. In H, Langdon-Embry M, Gordon L, Schechter CB, Wylie-Rosett J, Castle PE, et al. Can a gastric cancer risk survey identify high-risk patients for endoscopic screening? A pilot study. Journal of Surgical Research. 2018;227:246–56.

    Article  Google Scholar 

  11. Graham DY, Schwartz JT, Cain GD, Gyorkey F. Prospective evaluation of biopsy number in the diagnosis of esophageal and gastric carcinoma. Gastroenterology. 1982;82(2):228–31.

    Article  CAS  Google Scholar 

  12. Kim SJ, Kim HH, Kim YH, Hwang SH, Lee HS, Park DJ, et al. Peritoneal metastasis: detection with 16- or 64-detector row CT in patients undergoing surgery for gastric cancer. Radiology. 2009;253(2):407–15.

    Article  Google Scholar 

  13. Burbidge S, Mahady K, Naik K. The role of CT and staging laparoscopy in the staging of gastric cancer. Clinical radiology. 2013;68(3):251–5.

    Article  CAS  Google Scholar 

  14. Abdalla EK, Pisters PWT. Staging and preoperative evaluation of upper gastrointestinal malignancies. Seminars in Oncology. 2004;31(4):513–29.

    Article  Google Scholar 

  15. Yan C, Zhu ZG, Yan M, Zhang H, Pan ZL, Chen J, et al. Value of multidetector-row computed tomography in the preoperative T and N staging of gastric carcinoma: a large-scale Chinese study. Journal of surgical oncology. 2009;100(3):205–14.

    Article  Google Scholar 

  16. Mocellin S, Pasquali S. Diagnostic accuracy of endoscopic ultrasonography (EUS) for the preoperative locoregional staging of primary gastric cancer. The Cochrane database of systematic reviews. 2015(2):Cd009944.

    Google Scholar 

  17. Leake PA, Cardoso R, Seevaratnam R, Lourenco L, Helyer L, Mahar A, et al. A systematic review of the accuracy and indications for diagnostic laparoscopy prior to curative-intent resection of gastric cancer. Gastric cancer: official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2012;15 Suppl 1:S38–47.

    Article  Google Scholar 

  18. Feussner H, Omote K, Fink U, Walker SJ, Siewert JR. Pretherapeutic laparoscopic staging in advanced gastric carcinoma. Endoscopy. 1999;31(5):342–7.

    Article  CAS  Google Scholar 

  19. Al-Batran SE, Goetze TO, Mueller DW, Vogel A, Winkler M, Lorenzen S, et al. The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction - a phase III trial of the German AIO/CAO-V/CAOGI. BMC cancer. 2017;17(1):893.

    Article  Google Scholar 

  20. Paoletti X, Oba K, Burzykowski T, Michiels S, Ohashi Y, Pignon JP, et al. Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis. Jama. 2010;303(17):1729–37.

    Article  CAS  Google Scholar 

  21. Leitlinienprogramm Onkologie (Deutsche Krebsgesellschaft, Deutsche Krebshilfe, AWMF): S3-Leitlinie Magenkarzinom, Langversion 2.01 (Konsultationsfassung) 2019 [Available from: http://www.leitlinienprogrammonkologie.de/leitlinien/magenkarzinom/.

  22. Machairas N, Charalampoudis P, Molmenti EP, Kykalos S, Tsaparas P, Stamopoulos P, et al. The value of staging laparoscopy in gastric cancer. Annals of gastroenterology. 2017;30(3):287–94.

    PubMed  PubMed Central  Google Scholar 

  23. Choi KS, Jung HY, Choi KD, Lee GH, Song HJ, Kim DH, et al. EMR versus gastrectomy for intramucosal gastric cancer: comparison of long-term outcomes. Gastrointestinal endoscopy. 2011;73(5):942–8.

    Article  Google Scholar 

  24. Facciorusso A, Antonino M, Di Maso M, Muscatiello N. Endoscopic submucosal dissection vs endoscopic mucosal resection for early gastric cancer: A meta-analysis. World journal of gastrointestinal endoscopy. 2014;6(11):555–63.

    Article  Google Scholar 

  25. Pimentel-Nunes P, Dinis-Ribeiro M, Ponchon T, Repici A, Vieth M, De Ceglie A, et al. Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2015;47(9):829–54.

    Article  Google Scholar 

  26. Sasako M, Sano T, Yamamoto S, Kurokawa Y, Nashimoto A, Kurita A, et al. D2 lymphadenectomy alone or with para-aortic nodal dissection for gastric cancer. N Engl J Med. 2008;359(5):453–62.

    Article  CAS  Google Scholar 

  27. Tyrvainen T, Sand J, Sintonen H, Nordback I. Quality of life in the long-term survivors after total gastrectomy for gastric carcinoma. Journal of surgical oncology. 2008;97(2):121–4.

    Article  Google Scholar 

  28. Wu CW, Chiou JM, Ko FS, Lo SS, Chen JH, Lui WY, et al. Quality of life after curative gastrectomy for gastric cancer in a randomised controlled trial. British journal of cancer. 2008;98(1):54–9.

    Article  Google Scholar 

  29. Bozzetti F, Marubini E, Bonfanti G, Miceli R, Piano C, Gennari L. Subtotal versus total gastrectomy for gastric cancer: five-year survival rates in a multicenter randomized Italian trial. Italian Gastrointestinal Tumor Study Group. Ann Surg. 1999;230(2):170–8.

    Article  CAS  Google Scholar 

  30. Pu YW, Gong W, Wu YY, Chen Q, He TF, **ng CG. Proximal gastrectomy versus total gastrectomy for proximal gastric carcinoma. A meta-analysis on postoperative complications, 5-year survival, and recurrence rate. Saudi medical journal. 2013;34(12):1223–8.

    PubMed  Google Scholar 

  31. Japanese gastric cancer treatment guidelines 2014 (ver. 4). Gastric cancer: official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association. 2017;20(1):1–19.

    Article  Google Scholar 

  32. Smith DD, Schwarz RR, Schwarz RE. Impact of total lymph node count on staging and survival after gastrectomy for gastric cancer: data from a large US-population database. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2005;23(28):7114–24.

    Article  Google Scholar 

  33. Mocellin S, McCulloch P, Kazi H, Gama-Rodrigues JJ, Yuan Y, Nitti D. Extent of lymph node dissection for adenocarcinoma of the stomach. The Cochrane database of systematic reviews. 2015(8):Cd001964.

    Google Scholar 

  34. Songun I, Putter H, Kranenbarg EM, Sasako M, van de Velde CJ. Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial. Lancet Oncol. 2010;11(5):439–49.

    Article  Google Scholar 

  35. Smyth EC, Verheij M, Allum W, Cunningham D, Cervantes A, Arnold D. Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of oncology: official journal of the European Society for Medical Oncology. 2016;27(suppl 5):v38–v49.

    Article  CAS  Google Scholar 

  36. Ajani JA, D’Amico TA, Almhanna K, Bentrem DJ, Chao J, Das P, et al. Gastric Cancer, Version 3.2016, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network: JNCCN. 2016;14(10):1286–312.

    Article  Google Scholar 

  37. Nimptsch U, Haist T, Gockel I, Mansky T, Lorenz D. Complex gastric surgery in Germany-is centralization beneficial? Observational study using national hospital discharge data. Langenbecks Arch Surg. 2019;404(1):93–101.

    Article  Google Scholar 

  38. Chen XZ, Wen L, Rui YY, Liu CX, Zhao QC, Zhou ZG, et al. Long-term survival outcomes of laparoscopic versus open gastrectomy for gastric cancer: a systematic review and meta-analysis. Medicine (Baltimore). 2015;94(4):e454.

    Article  Google Scholar 

  39. Jacquet P, Sugarbaker PH. Clinical research methodologies in diagnosis and staging of patients with peritoneal carcinomatosis. Cancer treatment and research. 1996;82:359–74.

    Article  CAS  Google Scholar 

  40. Rau B, Brandl A, Piso P, Pelz J, Busch P, Demtroder C, et al. Peritoneal metastasis in gastric cancer: results from the German database. Gastric cancer: official journal of the International Gastric Cancer Association and the Japanese Gastric carcinomatosis from gastric cancer: a multi-institutional study of 159 patients treated by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy. Annals of surgical oncology. 2010;17(9):2370–7.

    Article  Google Scholar 

  41. Bonnot PE, Piessen G, Kepenekian V, Decullier E, Pocard M, Meunier B, et al. Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy for Gastric Cancer With Peritoneal Metastases (CYTO-CHIP study): A Propensity ScorCancer Association. 2019.

  42. Glehen O, Gilly FN, Arvieux C, Cotte E, Boutitie F, Mansvelt B, et al. Peritoneale Analysis. Journal of clinical oncology: official journal of the American Society of Clinical Oncology 2019:Jco1801688.

    Google Scholar 

  43. Fujitani K, Yang HK, Mizusawa J, Kim YW, Terashima M, Han SU, et al. Gastrectomy plus chemotherapy versus chemotherapy alone for advanced gastric cancer with a single non-curable factor (REGATTA): a phase 3, randomised controlled trial. Lancet Oncol. 2016;17(3):309–18.

    Article  CAS  Google Scholar 

  44. Guzman EA, Dagis A, Bening L, Pigazzi A. Laparoscopic gastrojejunostomy in patients with obstruction of the gastric outlet secondary to advanced malignancies. The American surgeon. 2009;75(2):129–32.

    PubMed  Google Scholar 

  45. Takeno A, Takiguchi S, Fujita J, Tamura S, Imamura H, Fujitani K, et al. Clinical outcome and indications for palliative gastrojejunostomy in unresectable advanced gastric cancer: multi-institutional retrospective analysis. Annals of surgical oncology. 2013;20(11):3527–33.

    Article  Google Scholar 

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Gassel, L.C., Reim, D., Novotny, A. et al. Vollständige Resektion Voraussetzung für entscheidende Prognoseverbesserung. Gastro-News 6, 36–41 (2019). https://doi.org/10.1007/s15036-019-0632-2

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