Abstract
Curcuma caesia or commonly known as black turmeric is belongs to family Zingiberaceae. The rhizome which is the most important part of this species is widely used as a folk medicine for the treatment of asthma, fever, cancer, wounds, allergies, toothache, leprosy, bronchitis, epilepsy, hemorrhoids, leukoderma and rheumatoid arthritis. C. caesia is one of the important species of Curcuma which possess various bioactive compounds that responsible for numerous pharmacological activities. The rhizome which is the most prominent feature of the plant is rich with essential oil. In addition, the leaves of this species also consist of essential oil with various bioactive compounds. This review article is aimed to discuss in-depth on botany, ethnomedicinal uses, geographical distribution, propagation, phytochemical studies, pharmacological activities and toxicity of C. caesia. The phytochemical studies revealed that a total of 17 functional groups were detected from rhizome extract of C. caesia. The pharmacological studies conducted demonstrated that C. caesia extract exhibited anti-acne, analgesic, anthelmintic, anti-asthmatic, anti-inflammatory, anti-bacterial, anti-fungal, anti-diabetic, antiproliferative, anticancer, antiulcer, hepatotoxicity, nephrotoxicity, neurotoxicity and cytotoxicity effects. Furthermore, toxicity studies revealed that C. caesia extract is safe for consumption and does not cause toxicity.
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This work was supported by Universiti Putra Malaysia.
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ZH: conceptualization, collection of information, data curation, drafting the manuscript and writing the manuscript. JJN and URS: supervision and review. MH: supervision, drafting the manuscript, editing and review the manuscript. All authors approved the final submitted version of the manuscript.
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Zainol Haida has no conflict of interest. Jaafar Juju Nakasha has no conflict of interest. Uma Rani Sinniah has no conflict of interest. Mansor Hakiman has no conflict of interest.
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Haida, Z., Nakasha, J.J., Sinniah, U.R. et al. Ethnomedicinal uses, phytochemistry, pharmacological properties and toxicology of Curcuma caesia Roxb.: a review. ADV TRADIT MED (ADTM) 23, 985–1001 (2023). https://doi.org/10.1007/s13596-022-00658-y
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DOI: https://doi.org/10.1007/s13596-022-00658-y