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Optimizing Surgical Treatment for Phyllodes Tumor

  • Local-Regional Evaluation and Therapy (DM Euhus, Section Editor)
  • Published:
Current Breast Cancer Reports Aims and scope Submit manuscript

Abstract

Purpose

This article aims to discuss the optimal surgical treatment for Phyllodes Tumor. A general overview of each grade will be presented along with relevant findings in recent literature. An argument for a modification to current practice standards and guidelines will be introduced as histological grading has become increasingly important.

Recent Findings

Based on our literature review, benign phyllodes tumors have a mean local recurrence rate of 6.9% and a mean distant metastasis rate of 0.01%. Recent studies have revealed there is no statistical difference in local recurrence for patients with positive or negative margins following tumor resection of the benign grade.

Summary

The National Comprehensive Cancer Network recommends wide local excisions with negative margins of 1 cm for all Phyllodes Tumors. However, we believe these guidelines are obsolete as the histological benign grade has extremely low rates of local recurrence and metastasis. In order to decrease patient morbidity, close surveillance and observation should be considered over standard practice following a positive margin in benign Phyllodes Tumors.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Author information

Authors and Affiliations

  1. Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China

    Kai Chen & Yanbo Chen

  2. Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China

    Kai Chen & Yanbo Chen

  3. Division of Surgical Oncology, Department of Surgery, Johns Hopkins University, Baltimore, MD, USA

    Paul Cartwright & Lisa Jacobs

Authors
  1. Kai Chen
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  2. Yanbo Chen
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  3. Paul Cartwright
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  4. Lisa Jacobs
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Corresponding author

Correspondence to Paul Cartwright.

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The authors declare that they have no competing interests.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Local-Regional Evaluation and Therapy

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Chen, K., Chen, Y., Cartwright, P. et al. Optimizing Surgical Treatment for Phyllodes Tumor. Curr Breast Cancer Rep 10, 55–61 (2018). https://doi.org/10.1007/s12609-018-0267-x

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  • DOI: https://doi.org/10.1007/s12609-018-0267-x

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